Stress granules at the crossroads of retroviral replication and antiviral immunity: mechanisms and therapeutic opportunities. [PDF]
Akbarin MM, Farjami Z, Álvarez HR.
europepmc +1 more source
This review surveys eukaryotic cilia as putative quantum‐enabled sensory and regulatory centers. It highlights their multifaceted roles in the cell, focuses on the nontrivial roles of quantum mechanics in their membrane and cytoskeletal proteins, and introduces the essential building blocks enabling quantum properties to survive in the warm, wet, and ...
Daniel L. Bilezikian +5 more
wiley +1 more source
A New Single-Chain, Genetically Encoded Biosensor for RhoB GTPase Based on FRET, Useful for Live-Cell Imaging. [PDF]
Pagano S, Hodgson L.
europepmc +1 more source
Aspartame Increases the Risk of Pancreatic Ductal Adenocarcinoma
Aspartame (APM) is a widely used artificial sweetener associated with various health concerns, including potential links to diabetes, cardiovascular diseases, and an increased risk of cancer. A comprehensive approach incorporating data mining, machine learning, network toxicology, molecular docking, molecular dynamics simulations, and clinical sample ...
Jumin Xie +5 more
wiley +1 more source
RHOA regulates mitochondria-ER contact sites through modulation of the VAPB/PTPIP51 tether. [PDF]
Yang Z +5 more
europepmc +1 more source
Genome‐Wide In Silico Analysis of the Type VI Secretion System (T6SS) Within the Morganella Genus
▪ Species‐specific T6SS patterns among Morganella genus (M. morganii and M. sibonii). ▪ Only one‐third of M. morganii isolates haboured a T6SS. ▪ All M. sibonii possess four T6SS clusters. ▪ M. sibonii exhibited a wide diversity of effectors compared to M. morganii.
Mathilde Duque +4 more
wiley +1 more source
Rac1 in gastric cancer: a molecular driver of invasion, EMT, and therapeutic resistance. [PDF]
Li J +5 more
europepmc +1 more source
Cilia in Nervous System Development, Function, and Disease
Cilia are evolutionarily conserved organelles that function as essential sensory and motility platforms in the nervous system. This review outlines key cilia‐dependent signaling pathways and their roles in neural development and function. Furthermore, it highlights how ciliary dysfunction can lead to a variety of neurological disorders, known as ...
Qingchao Li, Anqi Zhang, Ting Song
wiley +1 more source
The small GTPase Rab5 inhibits actin polymerization mediated by the Legionella pneumophila effector VipA. [PDF]
Saraiva J +6 more
europepmc +1 more source
Abstract A bottleneck for structure–function studies of closely related proteins is purification. Here, we built upon new affinity protein purification technology to develop a uniform and rapid tandem‐affinity purification protocol to generate significant quantities of pure GTPase proteins for use in structure–function studies. Our method relies on new
Rofiat Oladimeji +4 more
wiley +1 more source

