Role of mitochondrial translation in modulating inflammatory disease outcome: Current knowledge and future perspectives. [PDF]
Basu S +6 more
europepmc +1 more source
Dynamic disorder is crucial for mitochondrial protein import
Abstract The import of proteins into mitochondria poses fundamental mechanistic challenges: aggregation‐prone precursor proteins must be maintained in aqueous compartments and threaded through narrow pores without becoming stuck or mislocalized. Recent evidence from mitochondrial protein import studies and other chaperone systems underscores the ...
Jakob Schneider +3 more
wiley +1 more source
Cryo-EM structures of the tubulin cofactors reveal the molecular basis of alpha/beta-tubulin biogenesis. [PDF]
Taheri A +4 more
europepmc +1 more source
GPR56/ADGRG1 regulates development and maintenance of peripheral myelin [PDF]
Ackerman, Sarah D +9 more
core +1 more source
A Structural Context for the Mechanisms of Uncoupling Protein 1 in Brown Fat Thermogenesis
ABSTRACT Uncoupling Protein 1 (UCP1) is a defining feature of brown fat and facilitates the specialized ability of the tissue to generate heat in the process of non‐shivering thermogenesis. The protein is activated by fatty acids, which overcome its inhibition by purine nucleotides, to catalyze proton leak across the mitochondrial inner membrane ...
Riccardo Cavalieri +7 more
wiley +1 more source
Neuropathic Pain: Mapping the miRNA Landscape. [PDF]
García-Domínguez M.
europepmc +1 more source
GRKs and arrestins: Nomenclature and functions in GPCR‐dependent and ‐independent signalling
G protein‐coupled receptor (GPCR) kinases (GRKs) and arrestins play a critical role in the regulation of GPCR signalling. Historic names of mammalian GRKs were replaced by systematic ones in the 1990s; however, both kinds of names are currently in use for mammalian arrestins.
Vsevolod V. Gurevich
wiley +1 more source
Current interest in artificial cell research underscores its potential to deepen our understanding of life's fundamental processes. This review highlights advances in bottom‐up coacervate‐based artificial cell engineering via combined integration of cellular hallmarks.
Arjan Hazegh Nikroo +3 more
wiley +2 more sources
Regulation of Translation of ATF4 mRNA: A Focus on Translation Initiation Factors and RNA-Binding Proteins. [PDF]
Adjibade P, Mazroui R.
europepmc +1 more source
scRNA‐Seq reveals anti‐lymphoma immune responses in mogamulizumab‐associated skin eruptions
CCR4 was expressed in malignant clones and regulatory T cells in untreated CTCL, that were decreased in MAR. Malignant clones in MAR showed a silenced phenotype with decreases in central memory markers SELL and CCR7, and GTP‐binding member GIMAP7 and upregulation of MMP2 inhibitor TIMP2 and tumour suppressor gene RUNX3.
Shannon Meledathu +13 more
wiley +1 more source

