Results 31 to 40 of about 154,453 (348)

High throughput transcriptome profiling of lithium stimulated human mesenchymal stem cells reveals priming towards osteoblastic lineage. [PDF]

PLoS ONE, 2013
Human mesenchymal stem cells (hMSCs) present in the bone marrow are the precursors of osteoblasts, chondrocytes and adipocytes, and hold tremendous potential for osteoregenerative therapy.
Neeraj Kumar Satija, Deepa Sharma, Farhat Afrin, Rajendra P Tripathi, Gurudutta Gangenahalli   +4 more
doaj   +1 more source

Function and regulation of Rnd proteins in cortical projection neuron migration

Frontiers in Neuroscience, 2015
The mammalian cerebral cortex contains a high variety of neuronal subtypes that acquire precise spatial locations and form long or short-range connections to establish functional neuronal circuits.
Roberta eAzzarelli, Francois eGuillemot, Emilie ePacary, Emilie ePacary   +3 more
doaj   +1 more source

Identifying conformational changes with site-directed spin labeling reveals that the GTPase domain of HydF is a molecular switch [PDF]

, 2017
[FeFe]-hydrogenases catalyse the reduction of protons to hydrogen at a complex 2Fe[4Fe4S] center called H-cluster. The assembly of this active site is a multistep process involving three proteins, HydE, HydF and HydG.
Acquasaliente, Laura, Bortolus, Marco, Carbonera, Donatella, Costantini, Paola, DE FILIPPIS, Vincenzo, DE ROSA, Edith, Doni, Davide, Galazzo, Laura, Maso, Lorenzo   +8 more
core   +1 more source

The domain architecture of large guanine nucleotide exchange factors for the small GTP-binding protein Arf

BMC Genomics, 2005
BackgroundSmall G proteins, which are essential regulators of multiple cellular functions, are activated by guanine nucleotide exchange factors (GEFs) that stimulate the exchange of the tightly bound GDP nucleotide by GTP.
B. Mouratou, V. Biou, Alexandra Joubert, Jean Cohen, D. Shields, N. Geldner, G. Jürgens, P. Melançon, J. Cherfils   +8 more
semanticscholar   +1 more source

Actin re-organization induced by Chlamydia trachomatis serovar D--evidence for a critical role of the effector protein CT166 targeting Rac. [PDF]

PLoS ONE, 2010
The intracellular bacterium Chlamydia trachomatis causes infections of urogenital tract, eyes or lungs. Alignment reveals homology of CT166, a putative effector protein of urogenital C. trachomatis serovars, with the N-terminal glucosyltransferase domain
Jessica Thalmann, Katrin Janik, Martin May, Kirsten Sommer, Jenny Ebeling, Fred Hofmann, Harald Genth, Andreas Klos   +7 more
doaj   +1 more source

The Trimeric GTP-binding Protein (Gq/G11) α Subunit Is Required for Insulin-stimulated GLUT4 Translocation in 3T3L1 Adipocytes*

Journal of Biological Chemistry, 2000
To investigate the potential role of trimeric GTP-binding proteins regulating GLUT4 translocation in adipocytes, wild type and constitutively active Gq(Gq/Q209L), Gi (Gi/Q205L), and Gs (Gs/Q227L) α subunit mutants were expressed in 3T3L1 adipocytes ...
M. Kanzaki, R. Watson, N. Artemyev, J. Pessin   +3 more
semanticscholar   +1 more source

Nitric Oxide Mediates Biofilm Formation and Symbiosis in Silicibacter sp. Strain TrichCH4B. [PDF]

, 2015
UnlabelledNitric oxide (NO) plays an important signaling role in all domains of life. Many bacteria contain a heme-nitric oxide/oxygen binding (H-NOX) protein that selectively binds NO.
Marletta, Michael A, Rao, Minxi, Smith, Brian C   +2 more
core   +3 more sources

Vascular Growth in the Fetal Lung [PDF]

, 2011
The structure of the lung is truly remarkable. It is primarily composed of three branched tubular networks (the airway, pulmonary artery and vein, bronchial artery and vein) which supply blood and air to the site of gas exchange and which maintain ...
Land, Stephen
core   +4 more sources

RBEL1 Is a Novel Gene That Encodes a Nucleocytoplasmic Ras Superfamily GTP-binding Protein and Is Overexpressed in Breast Cancer*

Journal of Biological Chemistry, 2007
Rab family proteins are generally known as regulators of protein transport and trafficking. A number of Rab proteins have been implicated in cancer development and/or progression.
J. Montalbano, W. Jin, M. Sheikh, Ying Huang   +3 more
semanticscholar   +1 more source

Differential proteome analysis of pea roots at the early stages of symbiosis with nodule bacteria

Вавиловский журнал генетики и селекции, 2018
In this paper, we have analyzed changes in the proteomic spectrum of pea Pisum sativum L. roots during inoculation with rhizobial bacteria with the aim of revealing new regulators of symbiosis development. To study the changes in the proteome spectrum of
I. V. Leppyanen, A. N. Kirienko, A. A. Lobov, E. A. Dolgikh   +3 more
doaj   +1 more source