Results 221 to 230 of about 1,111,922 (385)

Mitochondrial fission protein 1 in the regulation of mitochondrial quality control: A cancer perspective

Interdisciplinary Medicine, EarlyView.
Background: Mitochondrial fission protein (FIS1), affecting energy metabolism and homeostasis, is crucial for mitochondrial quality control (MQC) and tumor progression. Key Points: It varies in expression across TME, influencing tumor progression.
Chao Wei, Xiaoling Yuan, Xiaoli Liu, Jia Feng, Miao Song, Xuexue Liu, Jiahong Zhou, Jinbo Liu   +7 more
wiley   +1 more source

Mitochondrial dysfunction: Related diseases, influencing factors, and detection

Interdisciplinary Medicine, EarlyView.
Mitochondrial dysfunction is implicated in the pathogenesis of numerous diseases, including neurological disorders, cancers, and cardiovascular conditions, through mechanisms such as mitochondrial DNA mutations, dysregulation of mitochondrial network dynamics, and impaired mitophagy.
Zhaojin Li, Shiyu Li, Wanying Chen, Ziyu Zhang, Chun Pan, Peng Lei, Cheng Cheng, Junyou Zhu, Hanxiao Sun, Zhenning Dai   +9 more
wiley   +1 more source

The binding of AP-1 clathrin adaptor particles to Golgi membranes requires ADP-ribosylation factor, a small GTP-binding protein

, 1993
Mark A. Stamnes, James E. Rothman
openalex   +1 more source

Coexistence of APC and KRAS Mutations in Familial Adenomatous Polyposis and Endometrial Cancer: A Mini‐Review With Case‐Based Perspective

Med Research, EarlyView.
ABSTRACT Familial adenomatous polyposis (FAP) is a well‐characterized hereditary colorectal cancer syndrome driven by germline mutations in the APC gene. KRAS mutations, although more common in sporadic colorectal and endometrial cancers, are rarely seen concurrently in patients with FAP.
Tongchuan Yin, Zhenhua Tan, Lanjin Bai, Haibo Lan, Tianliang Liu   +4 more
wiley   +1 more source

VPS21 encodes a rab5-like GTP binding protein that is required for the sorting of yeast vacuolar proteins.

, 1994
Bruce Horazdovsky, G. Busch, Scott D. Emr   +2 more
openalex   +1 more source

Ferroptosis in Pneumoconiosis: From Molecular and Cellular Mechanisms to Therapeutic Strategies

Med Research, EarlyView.
Targeting lung various cells to alleviate pneumoconiosis by suppressing ferroptosis. AAV9‐HGF, adeno‐associated virus‐hepatocyte growth factor; DFP, deferiprone; DHQ, dihydroquercetin; Fer‐1, ferrostatin‐1; IL‐1β, interleukin‐1β; NMN, nicotinamide mononucleotide; sh‐SLC39A14, shRNA targeting solute carrier family 39 member 14; si‐OC‐STAMP, siRNA ...
Mengli Yan, Jing Zhang, Gaili Ji, Xiaobin Fang, Chunheng Mo   +4 more
wiley   +1 more source

cDNA cloning of a human mRNA preferentially expressed in hematopoietic cells and with homology to a GDP-dissociation inhibitor for the rho GTP-binding proteins.

, 1993
Jean-Michel Lélias, Chaker N. Adra, Gerbug M. Wulf, Jean-Claude Guillemot, M. Khagad, Daniel Caput, Boon Leong Lim   +6 more
openalex   +1 more source

A slowly ADP-ribosylated pertussis-toxin-sensitive GTP-binding regulatory protein is required for vasopressin-stimulated Ca2+ inflow in hepatocytes [PDF]

, 1994
Leise A. Berven, Bernard P. Hughes, Greg J. Barritt   +2 more
openalex   +1 more source

Cloning of a Novel Family of Mammalian GTP-binding Proteins (RagA, RagBs, RagB1) with Remote Similarity to the Ras-related GTPases *

Journal of Biological Chemistry, 1995
A. Schürmann, A. Brauers, S. Maßmann, W. Becker, H. Joost   +4 more
semanticscholar   +1 more source

Mitochondrial transfer as a novel therapeutic approach in ischemic stroke treatment: Current challenges and future perspectives

Neuroprotection, EarlyView.
Cerebral ischemia is a serious neurological disease that mainly leads to pathological changes such as mitochondrial dysfunction, oxidative stress and iron death. Mitochondria play a key role in the regulation of cellular energy metabolism and oxidative stress, and their damage can lead to mitochondrial damage, reduced adenosine triphosphate production,
Shuchen Meng, Min Bai, Changsheng Ma, Bo Han, Mengyuan Duan, Liying Zhang, Jinfen Guo, Changku Shi, Ke Li, Maotao He   +9 more
wiley   +1 more source