Results 251 to 260 of about 140,887 (291)

Baishaoluoshi Decoction Mitigates Post‐Stroke Spasticity by Targeting Synaptic Plasticity Through the Nogo‐A/NgR Signaling Pathway

Brain and Behavior, Volume 16, Issue 1, January 2026.
Baishaoluoshi Decoction alleviates post‐stroke spasticity by downregulating inhibitory proteins (Nogo‐A/NgR) in the peri‐infarct brain region and reducing NgR/Olig2 co‐localization in oligodendrocytes, thereby enhancing synaptic plasticity. ABSTRACT Objective: This study systematically investigated the effects and molecular mechanisms of Baishaoluoshi ...
Xiongxing Sun, Shanshan Zeng, Shigao Lin, Lingying Wu, Xukun Tang, Jiajian Zhu, Yuhui Zhang, Lu Li, Ziming Chen, Xinyu Deng, Dahua Wu, Le Xie   +11 more
wiley   +1 more source

ZapA uses a two-pronged mechanism to facilitate Z ring formation in <i>Escherichia coli</i>. [PDF]

mLife
Cui Y, Gong H, Yan D, Li H, Yang W, Li Y, Chen X, Lutkenhaus J, Huang SY, Yang X, Du S.   +10 more
europepmc   +1 more source

The Potential of Phytochemicals to Overcome Multidrug Resistance in Metastatic Melanoma

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT Metastatic melanoma is the most lethal form of skin cancer, accounting for most skin cancer‐related deaths. Immunotherapies and targeted therapies have improved overall and progression‐free survival rates in metastatic melanoma patients. The effectiveness of these therapies decreases due to multidrug resistance (MDR).
Jacqueline Maphutha, Danielle Twilley, Mona Dawood, Thomas Efferth, Namrita Lall   +4 more
wiley   +1 more source

Mechanism of controlled radical initiation in radical SAM GTP 3',8-cyclase. [PDF]

Proc Natl Acad Sci U S A
Pang H, Li D, Wu Q, Zhang P, Yang W, Silakov A, Zhou P, Yokoyama K.   +7 more
europepmc   +1 more source

Rice Blast Pathogenesis and Resistance: Effector Strategies and Host Defense Mechanisms

Food and Energy Security, Volume 15, Issue 1, January/February 2026.
ABSTRACT Rice blast is the most significant disease affecting rice production, causing substantial yield loss and quality degradation. Previous studies have focused primarily on the genetic basis of pathogen resistance in rice. Recent studies have revealed the immune response mechanisms induced by pathogen‐associated molecular patterns in the pathogen ...
Lu Gan, Qihang Gui, Meimei Yang, Qian Xiang, Bing Yang, Panpan Yuan, Hongyu Chen, Shan He, Minjie Li, Zhengwu Zhao   +9 more
wiley   +1 more source

Termination of the integrated stress response. [PDF]

Science
De Miguel C, Thorkelsson SR, Fatalska A, Hodgson G, Wang C, Bertolotti A.   +5 more
europepmc   +1 more source

The mechanism of thioamide formation by the YcfA-YcfC system in 6-thioguanine biosynthesis. [PDF]

Nat Commun
Zhang L, Dou C, Yan W, Chen P, Jia X, Zhang N, Zhou D, Long Z, Zhang L, Zhu X, Cheng W.   +10 more
europepmc   +1 more source

YsxC is a placeholder for ribosomal protein uL2 during 50S ribosomal subunit assembly. [PDF]

Nucleic Acids Res
Seffouh A, Arpin D, Basu K, Ortega J.
europepmc   +1 more source

Interconnected roles of mitochondrial carrier proteins ANT, P_iT, and UCPs in proton transport. [PDF]

Front Mol Biosci
Tabefam M, Swanson HK, Smith MD, Jelokhani-Niaraki M.   +3 more
europepmc   +1 more source

Broad-Spectrum RAS Inhibition in Pancreatic Ductal Adenocarcinoma: Mechanistic Advances and Therapeutic Promise. [PDF]

Pharmaceuticals (Basel)
Alanazi FE, Alatawi Y, Alattar A, Alshaman R, Kotb AA, Hetta HF.   +5 more
europepmc   +1 more source