Results 31 to 40 of about 12,400 (144)

Cloning and characterization of ADP-ribosylation factor 1b from the olive flounder Paralichthys olivaceus

open access: yesFisheries and Aquatic Sciences, 2017
Small GTPases are well known as one of the signal transduction factors of immune systems. The ADP-ribosylation factors (ARFs) can be classified into three groups based on the peptide sequence, protein molecular weight, gene structure, and phylogenetic ...
So-Hee Son   +4 more
doaj   +1 more source

Evolutionary degeneration of septins into pseudoGTPases: impacts on a hetero-oligomeric assembly interface

open access: yesFrontiers in Cell and Developmental Biology, 2023
The septin family of eukaryotic proteins comprises distinct classes of sequence-related monomers that associate in a defined order into linear hetero-oligomers, which are capable of polymerizing into cytoskeletal filaments. Like actin and ⍺ and β tubulin,
Alya Hussain   +3 more
doaj   +1 more source

Length, Protein-Protein Interactions, and Complexity [PDF]

open access: yes, 2004
The evolutionary reason for the increase in gene length from archaea to prokaryotes to eukaryotes observed in large scale genome sequencing efforts has been unclear. We propose here that the increasing complexity of protein-protein interactions has driven the selection of longer proteins, as longer proteins are more able to distinguish among a larger ...
arxiv   +1 more source

ProNet DB: A proteome-wise database for protein surface property representations and RNA-binding profiles [PDF]

open access: yesarXiv, 2022
The rapid growth in the number of experimental and predicted protein structures and more complicated protein structures challenge users in computational biology for utilizing the structural information and protein surface property representation. Recently, AlphaFold2 released the comprehensive proteome of various species, and protein surface property ...
arxiv  

Molecular Characterization of GTP Binding Protein Gene in Dermatophyte Pathogen Trichophyton rubrum [PDF]

open access: yesIranian Journal of Public Health, 2006
Trichophyton rubrum (T. rubrum) is an anthropophilic dermatophyte that is distributed worldwide and causes common cutaneous disease such as mycosis. Although several properties of this fungus have been investigated so far, however a few studies were ...
F Noorbakhsh   +4 more
doaj   +2 more sources

Co-crystalization reveals the interaction between AtYchF1 and ppGpp

open access: yesFrontiers in Molecular Biosciences, 2022
AtYchF1 is an unconventional G-protein in Arabidopsis thaliana that exhibits relaxed nucleotide-binding specificity. The bindings between AtYchF1 and biomolecules including GTP, ATP, and 26S rRNA have been reported.
Ming-Yan Cheung   +4 more
doaj   +1 more source

A process model of Rho GTP-binding proteins

open access: yesTheoretical Computer Science, 2009
AbstractRho GTP-binding proteins play a key role as molecular switches in many cellular activities. In response to extracellular stimuli and with the help of regulators (GEF, GAP, Effector, GDI), these proteins serve as switches that interact with their environment in a complex manner.
Kahramanogullari, Ozan   +4 more
openaire   +2 more sources

Small GTPase Ran and Ran-binding proteins

open access: yesBiomolecular Concepts, 2012
Like many other small GTPases, Ran functions in eukaryotic cells as a molecular switch that cycles between GTP- and GDP-bound forms. Through the proper modulation of the GTP/GDP cycle, Ran functions with a number of Ran-binding proteins to control a ...
Nagai Masahiro, Yoneda Yoshihiro
doaj   +1 more source

Reconstructed evolutionary history of the yeast septins Cdc11 and Shs1

open access: yesG3: Genes, Genomes, Genetics, 2020
Septins are GTP-binding proteins conserved across metazoans. They can polymerize into extended filaments and, hence, are considered a component of the cytoskeleton.
Julie Takagi   +7 more
doaj   +1 more source

Kinetics and Thermodynamics of Membrane Protein Folding [PDF]

open access: yesBiomolecules 2014, 4(1), 354-373, 2014
Understanding protein folding has been one of the great challenges in biochemistry and molecular biophysics. Over the past 50 years, many thermodynamic and kinetic studies have been performed addressing the stability of globular proteins. In comparison, advances in the membrane protein folding field lag far behind. Although membrane proteins constitute
arxiv   +1 more source

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