Results 131 to 140 of about 4,605 (211)

Erythropoietin prevents endothelial dysfunction in GTP-cyclohydrolase I-deficient hph1 mice. [PDF]

J Cardiovasc Pharmacol, 2014
dʼUscio LV, Santhanam AV, Katusic ZS.
europepmc   +1 more source

Reaction mechanism of GTP cyclohydrolase I: Single turnover experiments using a kinetically competent reaction intermediate

, 2002
Elsevier Science Ltd.GTP cyclohydrolase I catalyses the transformation of GTP into dihydroneopterin 3'-triphosphate, which is the first committed precursor of tetrahydrofolate and tetrahydrobiopterin.
Fischer, M., Auerbach, G., Schramek, N., Bacher, A., Bracher, A., Huber, R., Nar, H.   +6 more
core  

Characterization of cerebral microvasculature in transgenic mice with endothelium targeted over-expression of GTP-cyclohydrolase I. [PDF]

Brain Res, 2015
Santhanam AV, d'Uscio LV, Katusic ZS.
europepmc   +1 more source

Transcriptional regulation of the GTP cyclohydrolase I gene via the NF-κB pathway by bacterial and viral immune stimulants. [PDF]

J Biochem
Ozawa M, Hara S, Sakamoto M, Suzuki T, Niiyama S, Kakihana Y, Ichinose H.   +6 more
europepmc   +1 more source

Regulation of Gtp Cyclohydrolase I by Alternative Splicing in Mononuclear Cells

, 2008
GTP cyclohydrolase I (GCH, EC 3.5.4.16) regulates the level of tetrahydrobiopterin and in turn the activities of nitric oxide synthase and aromatic amino acid hydroxylases.
Hwu, Wuh-Liang; Yeh, Hui-Ying; Fang, Shu-Wen; Chiang, Hao-Sen; Chiou, Yu-Wei; Lee, Yu-May, HWU, WUH-LIANG;CHIANG, HONG-SEN   +1 more
core  

Enhanced expression of GTP cyclohydrolase I in V-1-overexpressing PC12D cells.

, 2002
Three of the catecholamine-synthesizing enzymes, i.e., tyrosine hydroxylase (TH), aromatic L -amino acid decarboxylase, and dopamine b-hydroxylase, were earlier shown to be up-regulated in cloned PC12D cells overexpressing V-1, a cdc10/SWI6 ...
Toshiharu Nagatsu, Tohru Yamakuni, Hiroshi Ichinose, Takahiro Suzuki, Hidehito Inagaki   +4 more
core  

Molecular Chaperones Affect Gtp Cyclohydrolase I Mutations in Dopa- Responsive Dystonia

, 2008
Unstable GTP cyclohydrolase I (GCH) mutations in dopa- responsive dystonia (DRD) can exert a dominant-negative effect in the HeLa cell model , but in a batch of cells this effect could not be shown.
胡務亮;華國媛;李玉梅, HWU, WUH-LIANG;HWA, KUO-YUAN;LEE, YU- MAY   +1 more
core  

Co-ordinate Expression of GTP Cyclohydrolase I and Inducible Nitric Oxide Synthase in Rat Mesangial Cells

Pteridines, 1995
Plüss Christoph, Kunz Dieter, Redweik Udo, Blau Nenad, Pfeilschifter Josef   +4 more
doaj   +1 more source

Preserving mitochondrial function prevents the proteasomal degradation of GTP cyclohydrolase I. [PDF]

Free Radic Biol Med, 2012
Sharma S, Sun X, Kumar S, Rafikov R, Aramburo A, Kalkan G, Tian J, Rehmani I, Kallarackal S, Fineman JR, Black SM.   +10 more
europepmc   +1 more source

Riboflavin Biosynthesis: Mapping the Tagged Lines of a Complex Metabolic Design. [PDF]

Biochemistry
Hoffpauir ZA, Lamb AL.
europepmc   +1 more source