Results 1 to 10 of about 320,805 (407)

Developmental control of plant Rho GTPase nano-organization by the lipid phosphatidylserine

open access: yesScience, 2019
GTPase clustering in response to a hormone Some lipid variants that are rare in plasma membranes function as signaling components. Studying root tip cells of the model plant Arabidopsis, Platre et al.
Matthieu Pierre Platre   +2 more
exaly   +2 more sources

The dynamics of spatio-temporal Rho GTPase signaling: formation of signaling patterns [version 1; referees: 2 approved]

open access: yesF1000Research, 2016
Rho GTPases are crucial signaling molecules that regulate a plethora of biological functions. Traditional biochemical, cell biological, and genetic approaches have founded the basis of Rho GTPase biology.
Rafael Dominik Fritz, Olivier Pertz
doaj   +2 more sources

Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex

open access: yesScience, 2019
Cellular response to nutrient status An intricate regulatory mechanism is taking shape around control of the mechanistic target of rapamycin complex 1 (mTORC1) protein kinase complex. Physiological responses of cells to nutrient abundance is regulated by
Rosalie E Lawrence   +2 more
exaly   +2 more sources

Tyrosyl phosphorylation of KRAS stalls GTPase cycle via alteration of switch I and II conformation

open access: yesNature Communications, 2019
Deregulation of the RAS GTPase cycle due to mutations in RAS genes is commonly associated with cancer development. Here authors use NMR and mass spectrometry to shows that KRAS phosphorylation via Src alters the conformation of switch I and II regions ...
Yoshihito Kano   +18 more
doaj   +2 more sources

Abstract P-26: Staphylococcus Aureus 30S Ribosomal Subunit in a Complex with the Era GTPase: Sample Preparation for Cryo-EM [PDF]

open access: yesInternational Journal of Biomedicine, 2021
Background: An essential in bacteria GTPase Era is a multifunctional protein that is involved in cell cycle regulation and appears to play a significant role in ribosome biogenesis. It is required for the maturation of the 30S ribosomal subunit.
Evelina Klochkova   +5 more
doaj   +1 more source

Dynamin, a membrane-remodelling GTPase

open access: yesNature Reviews Molecular Cell Biology, 2012
Shawn M Ferguson
exaly   +2 more sources

Rho GTPase signalling in cell migration

open access: yesCurrent Opinion in Cell Biology, 2015
Anne J Ridley
exaly   +2 more sources

The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway

open access: hybridCell, 1992
Cecilia Bucci   +6 more
openalex   +2 more sources

Regulation of autophagy by the Rab GTPase network

open access: yesCell Death and Differentiation, 2014
X. Ao, L. Zou, Yuanyuan Wu
exaly   +2 more sources

Who’s in control? Principles of Rab GTPase activation in endolysosomal membrane trafficking and beyond

open access: yesJournal of Cell Biology, 2021
Borchers et al. review regulatory principles in the activation of endocytic Rab GTPases and how they apply to other Rab and Arf GTPases.
Ann-Christin Borchers   +2 more
semanticscholar   +1 more source

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