Results 211 to 220 of about 274,715 (359)

ARHGAP11A affects lung adenocarcinoma (LUAD) and pancreatic adenocarcinoma (PAAD) progression by regulating FAM83A. [PDF]

Transl Cancer Res
Sun K, Song LJ, Lu RQ, Liu QZ.
europepmc   +1 more source

The C‐Terminal Regions of TRAK Proteins Contain MIRO‐Independent Mitochondrial Localization Domains

Cytoskeleton, EarlyView.
ABSTRACT Current models suggest that MIRO GTPases anchor cytoskeletal motors to the mitochondrial outer membrane (MOM). However, our previous findings indicate that the unconventional myosin, MYO19, interacts with MIRO weakly and that a MIRO‐independent MOM‐localizing domain interacts more tightly with the MOM.
Lili Mitchell, Kathryn E. Reda, Hijab Fatima, Claudia E. Vasquez, Omar A. Quintero‐Carmona   +4 more
wiley   +1 more source

Rho GTPases signaling mediates aggressiveness and differentiation in neuroblastoma tumors. [PDF]

Cell Commun Signal
Gómez-Muñoz MA, Ojeda-Puertas M, Luna-Ramírez L, Amador-Álvarez A, Rodríguez-Prieto I, Cordero-Varela JA, Pardal R, Vega FM.   +7 more
europepmc   +1 more source

Charakterisierung des Diaphanous-verwandten Formins FHOD1 in der Regulation des Aktinzytoskeletts und seine Regulation durch Rho-GTPase-Signalwege

, 2014
Nina Schulze
openalex   +1 more source

The Influence of Drosophila Spire and Myosin V During Mid‐Oogenesis Is Independent of Their Direct Interaction

Cytoskeleton, EarlyView.
ABSTRACT Cooperativity between cytoskeletal proteins is crucial for spatiotemporal coordination in biological processes, like oogenesis. In mammalian and Drosophila oogenesis, proper assembly and function of actin networks require coordination between actin assembly factors Spire and formins, as well as actin‐associated proteins like myosins and Rab ...
Joseph Y. Ong, Hannah M. Bailey, Emma Carley, Michelle Panzica, Merin Rixen, Neil Billington, Rong Liu, Margot E. Quinlan   +7 more
wiley   +1 more source

An evolutionarily conserved salt bridge stabilizes the active site for GTP hydrolysis in Rho GTPases. [PDF]

J Biol Chem
Marcus K, Schwabe M, Knihtila R, Mattos C.   +3 more
europepmc   +1 more source

Expression, Purification, and Microscopy‐Based Assays for Engineered Recombinant Tyrosinated, Detyrosinated, and Δ2 Human Tubulin

Cytoskeleton, EarlyView.
ABSTRACT Microtubules are noncovalent polymers assembled from α/β tubulin dimers. Their structure, dynamics and interaction with effectors are regulated through the expression of diverse tubulin isotypes and chemically diverse posttranslational modifications, also known as the “tubulin code.” Understanding the biophysical correlates between tubulin ...
Jiayi Chen, Agnieska Szyk, Antonina Roll‐Mecak   +2 more
wiley   +1 more source

Distinct steps of nuclear maturation of human pre-60S complexes require the activity of GTPases including GNL3L. [PDF]

Nucleic Acids Res
Thomé CC, Lemus-Diaz N, Bloch von Blottnitz KI, Tagnères S, Klein Helmkamp M, Honemann-Capito M, Hackert P, Moshkovskii S, Lenz C, Bohnsack MT, Urlaub H, Bohnsack KE.   +11 more
europepmc   +1 more source

Mitochondria and the Actin Cytoskeleton in Neurodegeneration

Cytoskeleton, EarlyView.
ABSTRACT Mitochondrial dysfunction and cytoskeletal disorganization are widely recognized hallmarks of neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS).
Shivani Tuli, Preet Patel, Aneri Shethji, David Gau   +3 more
wiley   +1 more source

The upstream regulator, Rsr1p, and downstream effectors, Gic1p and Gic2p, of the Cdc42p small GTPase coordinately regulate initiation of budding in Saccharomyces cerevisiae [PDF]

, 2003
Ryosuke Kawasaki, Konomi Fujimura‐Kamada, Hirofumi Toi, Hiroyuki Kato, Kazuma Tanaka   +4 more
openalex   +1 more source