Results 21 to 30 of about 46,713 (191)

Introducing automation to the molecular diagnosis of Trypanosoma cruzi infection: A comparative study of sample treatments, DNA extraction methods and real-time PCR assays [PDF]

open access: yes, 2018
Background Polymerase chain reaction (PCR) has become a useful tool for the diagnosis of Trypanosoma cruzi infection. The development of automated DNA extraction methodologies and PCR systems is an important step toward the standardization of protocols ...
Abras, Alba   +12 more
core   +3 more sources

The N-Terminus of Apolipoprotein A-V Adopts a Helix-Bundle Molecular Architecture [PDF]

open access: yes, 2008
Previous studies of recombinant full-length human apolipoprotein A-V (apoA-V) provided evidence of the presence of two independently folded structural domains.
Beckstead, J. A.   +6 more
core   +3 more sources

Allosteric Activation of the Par-6 PDZ Via a Partial Unfolding Transition [PDF]

open access: yes, 2013
Proteins exist in a delicate balance between the native and unfolded states, where thermodynamic stability may be sacrificed to attain the flexibility required for efficient catalysis, binding, or allosteric control.
Kovrigin, Evgeni L.   +3 more
core   +2 more sources

Glepaglutide‐Loaded Foam for the Induction of Mucosal Healing in the Treatment of Inflammatory Bowel Disease

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Glepaglutide (GL), a GLP‐2 analog with an extended half‐life (50 h), is currently undergoing clinical trials for patients with short bowel syndrome. GL requires subcutaneous injection, which poses challenges for potential patient compliance. To address this challenge, we loaded GL into a rectal foam formulation using CO2 as a permeation enhancer to ...
Wunan Zhang   +9 more
wiley   +1 more source

Method of making contamination-free ceramic bodies [PDF]

open access: yes, 1991
Ceramic structures having high strength at temperatures above 1000 C after sintering are made by mixing ceramic powders with binder deflocculants such as guanidine salts of polymeric acids, guanidine salts of aliphatic organic carboxylic acids or ...
Philipp, Warren H.
core   +1 more source

Fabrication of a Lipopolysaccharide‐Targeting Peptide‐Based Colloid for Alleviating Carbapenem‐Resistant Enterobacteriaceae‐Induced Cutaneous Infection

open access: yesAdvanced Healthcare Materials, EarlyView.
In this study, a novel cationic peptide, IW is designed and synthesized, with a tandem‐repeat sequence demonstrating potent activities against a broad spectrum of clinically relevant Carbapenem‐resistant Enterobacteriaceae in both the planktonic and biofilm states. IW is then formulated with P407 to form IW‐P407 colloids.
Ping Zeng   +5 more
wiley   +1 more source

The Deepest Blue: Major Advances and Challenges in Deep Blue Emitting Quasi‐2D and Nanocrystalline Perovskite LEDs

open access: yesAdvanced Materials, EarlyView.
In this review, the recent development of deep‐blue (≤465 nm) perovskite light‐emitting diodes (PeLEDs) are summarized, using different perovskite nanomaterials, including nanocrystals (NCs), quantum dots (QDs), nanoplatelets (NPLs), quasi‐2D thin film, 3D bulk thin film, as well as lead‐free perovskite nanomaterials.
Pui Kei Ko   +6 more
wiley   +1 more source

Structural plasticity of the feline leukaemia virus fusion peptide: a circular dichroism study [PDF]

open access: yes, 1998
The secondary structure of the feline leukaemia virus (FeLV) fusion peptide was investigated using circular dichroism (CD). Our results show that this peptide can readily flip between random, α-helical and β-sheet conformations, depending upon its ...
Blobel   +23 more
core   +1 more source

State‐of‐the‐Art, Insights, and Perspectives for MOFs‐Nanocomposites and MOF‐Derived (Nano)Materials

open access: yesAdvanced Materials, EarlyView.
Different approaches to MOF‐NP composite formation, such as ship‐in‐a‐bottle, bottle‐around‐the‐ship and in situ one‐step synthesis, are used. Owing to synergistic effects, the advantageous features of the components of the composites are beneficially combined, and their individual drawbacks are mitigated.
Stefanos Mourdikoudis   +6 more
wiley   +1 more source

Shrink wrapping redox-active crystals of polyoxometalate open frameworks with organic polymers via crystal induced polymerisation [PDF]

open access: yes, 2016
We report examples of crystal surface modification of polyoxometalate open frameworks whereby the use of pyrrole or aniline as monomers leads to the formation of the corresponding polymers via an oxidative polymerization process initiated by the redox ...
Cronin, Lee   +3 more
core   +1 more source

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