Results 61 to 70 of about 55,046 (163)
Graphical abstract illustrating the pharmacological potential of E. spinosa. ABSTRACT Emex spinosa (L.) Campd. (E. spinosa) is a plant species belonging to the Polygonaceae family. It is native to the Middle East, North Africa, and Europe and is most commonly seen on the coastlines of Mediterranean countries.
Smail Amtaghri +9 more
wiley +1 more source
ABSTRACT Background Leonurine (LEO), a bioactive alkaloid derived from the Leonurus genus, exhibits diverse pharmacological activities including uterotonic, antioxidant, anti‐inflammatory, antiapoptotic, Antitumor, and vasoprotective effects. This review aims to provide a comprehensive overview of LEO's pharmacokinetics, pharmacological mechanisms ...
Zhouyue Gu
wiley +1 more source
Uncovering the role of genetic polymorphisms in cervical insufficiency
Pathways and genes implicated in CI pathogenesis. Abstract Cervical insufficiency (CI) is characterized by spontaneous dilation of the cervix in the absence of painful uterine contractions in the mid‐trimester, leading to premature delivery. It is responsible for up to 20% of second trimester pregnancy losses, mostly <24 weeks.
Kallirhoe Kalinderi +3 more
wiley +1 more source
Cationic poly(2‐oxazoline)s (POx) have emerged as versatile materials for different biomedical applications. The combination of the pseudo‐peptidic polymer backbone and the amine‐derived cationic motifs results in well‐tolerated polymers with potential benefits for drug and gene delivery as well as antimicrobial development.
Meike N. Leiske
wiley +1 more source
The review provides a comprehensive analysis of microbiome‐mediated oncogenic mechanisms in various cancers, emphasizing the unique therapeutic strategies facilitated by nanotechnology. It aims to fill this gap by systematically reviewing nanotechnology‐driven strategies for microbiome elimination, with a focus on their ability to improve the cold TME ...
Yumei Gan, Yan Zhang, Xia Dong, Feng Lv
wiley +1 more source
ABSTRACT Periodontitis is a chronic infectious oral disease triggered by periodontopathogenic bacteria, resulting in the progressive inflammation and destruction of the tissues surrounding teeth. To achieve reprogramming of the infectious microenvironment for periodontitis therapy, a nanoformulation was proposed by loading polydopamine (PDA) with ...
Hao Liang +14 more
wiley +1 more source
ABSTRACT Perovskite quantum dots (QDs) have been considered as promising emitters for lighting and display applications, but they suffer from poor thermal stability under operation. Herein, we introduce sub‐micrometer Ag particles to simultaneously enhance the luminescence intensity and thermal stability of perovskite QDs.
Zhihao Feng +5 more
wiley +1 more source
Electroelution Into a Salt Trap: Reviving an Old‐School Approach to DNA Purification
Electroelution into a salt cushion is a well‐established yet underutilized method of capturing gel‐purified nucleic acids. This Perspective discusses how this traditional method can be reengineered to meet the demands of next‐generation technologies, such as long‐read sequencing.
Ruslan Kalendar +4 more
wiley +1 more source
Molecular and Serological Detection of Coxiella burnetii in Small Ruminants in Northeastern Brazil
• Serology indicates that one‐third of the sheep and goats had previously been infected with Coxiella burnetii. • qPCR analysis revealed the ongoing presence of C. burnetii in all evaluated flocks, each with a previous history of reproductive disorders. • These results indicate the need for preventive measures and control of C.
Ana Karoline Sousa Mendes Simas +7 more
wiley +1 more source
Predictive, Data‐Driven Design of Red‐Light Photoredox Catalysts for C─Heteroatom Bond Formation
From redox numbers to red light: Donor oxidation and core reduction potentials predict E0‐0 in cyanoarene dyes, guiding selection of an efficient red‐light catalyst, 4MeODPATPN (PC13). Under 620 nm light, PC13 facilitates Ni‐catalyzed C─heteroatom cross‐couplings (C─N, C─O, C─S) with high functional‐group tolerance and reduced hydrodehalogenation ...
Amir Gizatullin +6 more
wiley +2 more sources

