Results 71 to 80 of about 133,980 (384)

Supramolecular Thermo Aero-able Gelators (STAGs) for synthesis of hydrogels

, 2012
Supramolecular Thermo Aero-able Gelators (STAGs): tartaric acid, urea, and guanidine with amide and imine moieties as supramolecular synthons are introduced to cross-link and aerate ('aero-able') polyacrylate networks for synthesis of hydrogels. They are
Atharva Sahasrabudhe, Dan Dan Yuan, Dianyu Chen, Feng Feng Xue, Peng Wang, Rongxin Yuan, Soumyajit Roy, Subharanjan Biswas, Xiao-Yan Tang   +8 more
core   +1 more source

Neddylation Targets and Stabilizes NLRP3 to Augment Inflammasome‐Mediated Colitis and Mood Disorder

Advanced Science, EarlyView.
NLRP3 inflammasome contributes to colitis and mood disorder. This study demonstrates that neddylation targets NLRP3 at K287, which hinders its interaction with K48‐linked ubiquitination E3 Trim31 and thereby stabilizes it. Neddylation blockade in myeloid cells and microglia mitigates DSS‐induced colitis and psychological stress‐induced anxiety‐like ...
Wenbin Gai, Mengyao Wu, Anbiao Wu, Zhaofei Jing, Zhenjie Ye, Jiayan Jin, Yaolin Zhang, Min Zhao, Genyu Liu, Xu Wang, Xiqin Yang, Jie Dong, Yunlu Xu, Jiyan Zhang   +13 more
wiley   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Development of Guanidine-Bisurea Bifunctional Organocatalysts with a Chiral Pyrrolidine Moiety and Application to α-Hydroxylation of Tetralone-Derived β-Keto Esters

Molecules, 2015
Novel guanidine-bisurea bifunctional organocatalysts 5 bearing a chiral pyrrolidine moiety on guanidine were designed with the guidance of DFT calculations.
Minami Odagi, Kan Takayama, Makoto Sato, Masahiro Yamanaka, Kazuo Nagasawa   +4 more
doaj   +1 more source

All‐Round Talent: Unique Zinc Guanidine Catalyst Performs Efficiently in Synthesis and Chemical Recycling of (Bio)Polyesters

Advanced Science, EarlyView.
A new zinc hybrid guanidine catalyst [Zn{(R,R)TMGNMe2(1,2)ch}2](OTf)2 (C1) shows very high catalytic activity in the polymerization of cyclic esters and in the depolymerization of these polyesters. Using C1 in the ring‐opening polymerization of lactide and caprolactone under industrially relevant conditions, astonishing rate constants of the same order
Tabea Becker, Koki Takeuchi, Carolin Süßmuth, Frederico Boekhoff, Martin A. Schäfer, Shunsuke Kato, Alexander Hoffmann, Takashi Hayashi, Sonja Herres‐Pawlis   +8 more
wiley   +1 more source

Reactivity of Zinc Halide Complexes Containing Camphor-Derived Guanidine Ligands with Technical rac-Lactide

Inorganics, 2017
Three new zinc complexes with monoamine–guanidine hybridligands have been prepared, characterized by X-ray crystallography and NMR spectroscopy, and tested in the solvent-free ring-opening polymerization of rac-lactide.
Angela Metz, Joshua Heck, Clara Marie Gohlke, Konstantin Kröckert, Yannik Louven, Paul McKeown, Alexander Hoffmann, Matthew D. Jones, Sonja Herres-Pawlis   +8 more
doaj   +1 more source

Bioactive Molecules – Polycyclic Guanidine Derivatives [PDF]

Kemija u Industriji, 2015
Biological activity of different adamantane derivatives and their application has been described in various reviews. Similarly, many reviews deal with biological activity and application of guanidine compounds.
M. Šekutor , K. Mlinarić-Majerski
doaj   +1 more source

Denoising Low-Power CEST Imaging Using a Deep Learning Approach With a Dual-Power Feature Preparation Strategy. [PDF]

Magn Reson Med
ABSTRACT Purpose: Low‐power (LP) chemical exchange saturation transfer (CEST) Z‐spectra have significantly reduced confounding effects and enhanced peak resolvability, thereby improving the observation and quantification of various CEST effects. However, LP Z‐spectra suffer greatly from reduced contrast‐to‐noise ratio (CNR).
Kurmi Y, Viswanathan M, Yin L, Chen Y, Jiang X, Xu J, Zu Z.   +6 more
europepmc   +2 more sources

Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs‐Derived Neuronal Model

Advanced Science, EarlyView.
Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian, Yi‐Chun Ou, Zi‐Xian Zhang, Jie Cai, Si‐Qing Cai, Guo‐Gang Xing   +5 more
wiley   +1 more source

An Inverted-Sandwich Dichromium(I) Complex Stabilized by Guanidinate Ligands

Molbank
Reduction of the four-coordinate “ate” species [(RC(NAr)2Cr(µ-Cl)2Li(THF)2] (1) (R = diisopropylamine; Ar = 2,6-diisopropylphenyl) with potassium graphite (KC8) in toluene leads to the formation of a toluene-bridged inverted-sandwich dichromium(I ...
Awal Noor, Sadaf Qayyum, Andre Dickert, Mohamed El Oirdi   +3 more
doaj   +1 more source