Results 41 to 50 of about 158,534 (314)
Calculation of the Stabilization Energies of Oxidatively Damaged Guanine Base Pairs with Guanine [PDF]
Molecules, 2012 DNA is constantly exposed to endogenous and exogenous oxidative stresses. Damaged DNA can cause mutations, which may increase the risk of developing cancer and other diseases. G:C-C:G transversions are caused by various oxidative stresses. 2,2,4-Triamino-5(2H)-oxazolone (Oz), guanidinohydantoin (Gh)/iminoallantoin (Ia) and spiro-imino-dihydantoin (Sp ...
Suzuki, Masayo +5 more
openaire +4 more sources
The Two Faces of the Guanyl Radical: Molecular Context and Behavior
Molecules, 2021 The guanyl radical or neutral guanine radical G(-H)• results from the loss of a hydrogen atom (H•) or an electron/proton (e–/H+) couple from the guanine structures (G). The guanyl radical exists in two tautomeric forms.
Chryssostomos Chatgilialoglu
doaj +1 more source
Gut and Liver, 2020 Background/Aims: Renal toxicity is a concern in patients with chronic hepatitis B taking nucleotide analogues, such as adefovir (ADV) and tenofovir disoproxil fumarate (TDF).
Young Youn Cho +8 more
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Electronic properties of guanine-based nanowires [PDF]
Sol. St. Commun. 113, 577 (2004)., 2004 We present a first-principle study of the electronic and conduction properties of a few classes of nanowires constituted of guanine (G) molecules, self-assembled in different geometries. We first analyze the effect of the vertical $\pi$-$\pi$ interaction in model G-stack columns.
arxiv +1 more source
Analysis &Sensing, Volume 3, Issue 1, January 2023., 2023 Lanthanide complexes are ideal donors for FRET (Förster resonance energy transfer) assays with a variety of applications from easy‐to‐use quantitation of proteins to sophisticated experiments giving real‐time information on the movement of proteins. This Review article introduces the principles of using such assays before surveying the full scope of ...
Simon Wheeler, Stephen J. Butler
wiley +1 more source
A new possible way for cancer cure – DNA four strand [PDF]
World Cancer Research Journal, 2019 DNA is the active ingredient of all the biological operations of the cell because it stores genetic information in the configuration of genes. It is a very well recognized fact that DNA has a double-helical structure; recently, it was reported to have ...
P. Amit, K. Prerna, S. Anita, S. Kumar
doaj +1 more source
Charge transport-mediated recruitment of DNA repair enzymes [PDF]
Journal of Chemical Physics, 129, 235101, (2008), 2008 Damaged or mismatched bases in DNA can be repaired by Base Excision Repair (BER) enzymes that replace the defective base. Although the detailed molecular structures of many BER enzymes are known, how they colocalize to lesions remains unclear. One hypothesis involves charge transport (CT) along DNA [Yavin, {\it et al.}, PNAS, {\bf 102}, 3546, (2005 ...
arxiv +1 more source
IUCrJ, 2018 This paper presents experimental charge-density studies of cytosinium chloride, adeninium chloride hemihydrate and guaninium dichloride crystals based on ultra-high-resolution X-ray diffraction data and extensive theoretical calculations.
Prashant Kumar +3 more
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Multiscale QM/MM Molecular Dynamics Study on the First Steps of Guanine-Damage by Free Hydroxyl Radicals in Solution [PDF]
J. Phys. Chem. A 116, 3940 (2012), 2012 Understanding the damage of DNA bases from hydrogen abstraction by free OH radicals is of particular importance to reveal the effect of hydroxyl radicals produced by the secondary effect of radiation. Previous studies address the problem with truncated DNA bases as ab-initio quantum simulation required to study such electronic spin dependent processes ...
arxiv +1 more source
Binding Group of Oligonucleotides on TiO 2 Surfaces: Phosphate Anions or Nucleobases? [PDF]
, 2021 Although the immobilization of oligonucleotides (nucleic acid) on mineral surfaces is at the basis of different biotechnological applications, an atomistic understanding of the interaction of the nucleic acid components with the titanium dioxide surfaces has not yet been achieved.
arxiv +1 more source