Results 41 to 50 of about 320,673 (337)

Products of Oxidative Guanine Damage Form Base Pairs with Guanine [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
Among the natural bases, guanine is the most oxidizable base. The damage caused by oxidation of guanine, commonly referred to as oxidative guanine damage, results in the formation of several products, including 2,5-diamino-4H-imidazol-4-one (Iz), 2,2,4-triamino-5(2H)-oxazolone (Oz), guanidinoformimine (Gf), guanidinohydantoin/iminoallantoin (Gh/Ia ...
Katsuhito Kino   +4 more
openaire   +2 more sources

Intracellular metabolites in marine microorganisms during an experiment evaluating microbial mortality [PDF]

open access: yes, 2020
© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Longnecker, K., & Kujawinski, E. B.
Kujawinski, Elizabeth B.   +1 more
core   +1 more source

An organometallic compound which exhibits a DNA topology-dependent one-stranded intercalation mode [PDF]

open access: yes, 2016
Understanding how small molecules interact with DNA is essential since it underlies a multitude of pathological conditions and therapeutic interventions.
Adhireksan   +16 more
core   +2 more sources

Platinum Compound on Gold–Magnesia Hybrid Structure: A Theoretical Investigation on Adsorption, Hydrolysis, and Interaction with DNA Purine Bases

open access: yesNanomaterials
Cisplatin-based platinum compounds are important clinical chemotherapeutic agents that participate in most tumor chemotherapy regimens. Through density-functional theory calculations, the formation and stability of the inorganic oxide carrier, the ...
Zhenjun Song   +6 more
doaj   +1 more source

G-quartet biomolecular nanowires

open access: yes, 2002
We present a first-principle investigation of quadruple helix nanowires, consisting of stacked planar hydrogen-bonded guanine tetramers. Our results show that long wires form and are stable in potassium-rich conditions.
Calzolari, A.   +3 more
core   +1 more source

Synergistic Regulation of Pigment Cell Precursors’ Differentiation and Migration by ednrb1a and ednrb2 in Nile Tilapia

open access: yesCells
The evolutionary loss of ednrb2 in specific vertebrate lineages, such as mammals and cypriniform fish, raises fundamental questions about its functional necessity and potential redundancy or synergy with paralogous endothelin receptors in pigment cell ...
Zilong Wen   +7 more
doaj   +1 more source

Application of Ammonium Persulfate for Selective Oxidation of Guanines for Nucleic Acid Sequencing

open access: yesMolecules, 2017
Nucleic acids can be sequenced by a chemical procedure that partially damages the nucleotide positions at their base repetition. Many methods have been reported for the selective recognition of guanine.
Yafen Wang   +7 more
doaj   +1 more source

The Origin of Life: Models and Data. [PDF]

open access: yes, 2017
A general framework for conventional models of the origin of life (OOL) is the specification of a 'privileged function.' A privileged function is an extant biological function that is excised from its biological context, elevated in importance over other
Lanier, Kathryn A, Williams, Loren Dean
core   +1 more source

Modulation of guanine deaminase [PDF]

open access: yesBiochemical Journal, 1973
1. Guanine deaminases purified from the 15000g supernatant fraction of iso-osmotic sucrose homogenates of rat and mouse liver and brain were tested for the influence of GTP and allantoin. 2. The suffixes A and B were assigned to the isoenzyme fractions eluted from DEAE-cellulose with the lower and the higher molarity of eluent respectively. Isoenzyme A
K S, Kumar   +2 more
openaire   +2 more sources

Protonated nucleobases are not fully ionized in their chloride salt crystals and form metastable base pairs further stabilized by the surrounding anions

open access: yesIUCrJ, 2018
This paper presents experimental charge-density studies of cytosinium chloride, adeninium chloride hemihydrate and guaninium dichloride crystals based on ultra-high-resolution X-ray diffraction data and extensive theoretical calculations.
Prashant Kumar   +3 more
doaj   +1 more source

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