Results 131 to 140 of about 99,476 (367)
Identification of Human Proteins vulnerable to multiple Organisms and their disease associations [PDF]
arXiv, 2016 While most studies emphasize on certain aspects of Pathogen-Host Interactions (PHI), such as the preferential attachment of bacteria or virus to its human receptor homolog, studies have attempted to methodically classify interactions among pathogenic proteins and their host proteins.
arxiv
Complete RNA inverse folding: computational design of functional hammerhead ribozymes
, 2014 Nanotechnology and synthetic biology currently constitute one of the most innovative, interdisciplinary fields of research, poised to radically transform society in the 21st century. This paper concerns the synthetic design of ribonucleic acid molecules,
Clote, Peter +5 more
core +1 more source
LncRNA UCA1 Participates in De Novo Synthesis of Guanine Nucleotides in Bladder Cancer by Recruiting TWIST1 to Increase IMPDH1/2. [PDF]
Int J Biol Sci, 2023 Liu SS +5 more
europepmc +1 more source
Selective [9‐15N] Guanosine for Nuclear Magnetic Resonance Studies of Large Ribonucleic Acids
ChemBioChem, EarlyView.The small chemical shift anisotropy of nitrogen‐15 at the 9‐position in guanine (15N9‐G) leads to long T2 values and narrow NMR lines, particularly attractive to probe structure and dynamics of large (>200 nucleotide) ribonucleic acids (RNAs). RNAs regulate various cellular processes using malleable 3D structures, and understanding the factors that ...
Solomon K. Attionu +5 more
wiley +1 more source
Quadruplexes In ‘Dicty’: Crystal Structure Of A Four-Quartet G-Quadruplex Formed By G-Rich Motif Found In The Dictyostelium Discoideum Genome [PDF]
, 2018 Guanine-rich DNA has the potential to fold into non-canonical G-quadruplex (G4) structures. Analysis of the genome of the social amoeba Dictyostelium discoideum indicates a low number of sequences with G4-forming potential (249–1055).
Armane, S. +6 more
core +2 more sources
Advancing the Exploration of the Ubiquitin‐like Protein FUBI with Synthetic Chemical Tools
ChemBioChem, Accepted Article.The Ubiquitin‐like protein FUBI is encoded in humans by the FAU gene, whose down‐regulation in prostate, ovarian and breast cancer is significantly associated with poor prognosis. Despite its implications in disease progression, the regulatory mechanisms orchestrated by FUBI remain elusive. To address this knowledge gap, we developed a linear synthetic
Francesca D'Amico +8 more
wiley +1 more source
PLoS ONE, 2015 In recent years, the number of human infection cases produced by the food related species Saccharomyces cerevisiae has increased. Whereas many strains of this species are considered safe, other 'opportunistic' strains show a high degree of potential ...
Roberto Pérez-Torrado +5 more
doaj +1 more source
BMC Evolutionary Biology, 2019 Background Among the four bases, guanine is the most susceptible to damage from oxidative stress. Replication of DNA containing damaged guanines results in G to T mutations.
Sidra Aslam +5 more
doaj +1 more source
Effect of Stress on Blood Levels of Guanine Nucleotides.
Experimental Biology and Medicine, 1966 SummaryStudies using C14-labelled guanylic acid demonstrated a rapid disappearance of these substances from the blood of intact and adrenalectomized rats. The application of tourniquets across the hind limbs of these animals produced a significantly decreased clearance of the label from the blood after the tourniquet was removed.
E. R. Ramey, Vincent W. Hollis
openaire +3 more sources
ChemBioChem, Accepted Article.Upon cell stimulation, mammalian cells activate various signaling proteins and lipids by recruiting their upstream regulators to the inner leaflet of the plasma membrane (PM), which in turn determines their cellular response. Therefore, artificially inducing protein translocation to the PM is an effective strategy for dissecting cell signaling networks
Shuya Ohira +3 more
wiley +1 more source