Results 221 to 230 of about 99,476 (367)

Independent Avian Epigenetic Clocks for Ageing and Development

Molecular Ecology Resources, EarlyView.
ABSTRACT Information on individual age is a fundamental aspect in many ecological and evolutionary studies. However, accurate and non‐lethal methods that can be applied to estimate the age of wild animals are often absent. Furthermore, since the process of ageing is accompanied by a physical decline and the deterioration of biological functions, the ...
Ayke Haller, Judith Risse, Bernice Sepers, Kees van Oers   +3 more
wiley   +1 more source

Nicotinamide Riboside Supplementation Benefits in Patients With Werner Syndrome: A Double‐Blind Randomized Crossover Placebo‐Controlled Trial

Aging Cell, EarlyView.
Nicotinamide riboside improved arterial stiffness (cardio–ankle vascular index), reduced skin ulcer area, and showed a trend toward mitigating heel pad thinning in patients with Werner syndrome, with no serious adverse events. Metabolomic analysis revealed a significant decrease in creatinine, suggesting a potential suppression of renal functional ...
Mayumi Shoji, Hisaya Kato, Masaya Koshizaka, Hiyori Kaneko, Yusuke Baba, Takahiro Ishikawa, Naoya Teramoto, Daisuke Kinoshita, Ayano Yamaguchi, Yukari Maeda, Yosuke Inaba, Yuki Shiko, Yoshihito Ozawa, Vilhelm A. Bohr, Yoshiro Maezawa, Koutaro Yokote   +15 more
wiley   +1 more source

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

The D2-dopamine receptor of anterior pituitary is functionally associated with a pertussis toxin-sensitive guanine nucleotide binding protein.

, 1987
Susan E. Senogles, Jeffrey Benovic, N Amlaiky, Cecilia G. Unson, Graeme Milligan, R Vinitsky, Allen M. Spiegel, Marc G. Caron   +7 more
openalex   +1 more source

Metformin and Dietary Restriction Counteract Aging via Reducing m6A–Dependent Stabilization of Methionine Synthase mRNA in Brachionus asplanchnoidis (Rotifera)

Aging Cell, EarlyView.
Metformin and dietary restriction modulate m6A to extend lifespan of rotifer, highlighting MTR as a central regulator of aging through methionine metabolism. ABSTRACT Metformin, a medication primarily used to treat diabetes, has gained attentions for its potential antiaging properties.
Yu Zhang, Xiaojie Liu, Hairong Lian, Yanchao Chai, Yang Zhou, Dongqi Kan, Jilong Ren, Cui Han, Jiaxin Yang   +8 more
wiley   +1 more source

Activation of adenylate cyclase by the diterpene forskolin does not require the guanine nucleotide regulatory protein.

, 1981
Kenneth B. Seamon, John W. Daly
openalex   +1 more source

Complex population genetic structure of the bark beetle predator Thanasimus formicarius (L.) (Coleoptera: Cleridae) across its European range

Agricultural and Forest Entomology, EarlyView.
Abstract Thanasimus formicarius (L.) (Coleoptera: Cleridae) is an important bark beetle predator and can reduce bark beetle population densities of some of the most severe forest pests in Europe. We analysed the population genetics and phylogeography of T.
Eva Papek, Amina Derlić, Markus Melin, Alain Roques, Dragos Cocos, Martin L. Schroeder, Milan Pernek, Dimitrios N. Avtzis, Paulius Zolubas, David T. Williams, Juan A. Pajares, Oğuzhan Sarikaya, Roman Pavlin, Sevdalin Belilov, Martin M. Gossner, M. Lukas Seehausen, Anna Wierzbicka, Lara Kundtner, Christian Stauffer, Martin Schebeck   +19 more
wiley   +1 more source

Short Chain Alcohols Activate Guanine Nucleotide-dependent Phosphoinositidase C in Turkey Erythrocyte Membranes

, 1989
T.A. Rooney, R. Hager, Emanuel Rubin, Andrew P. Thomas   +3 more
openalex   +1 more source

Purification and immunochemical characterization of the major pertussis‐toxin‐sensitive guanine‐nucleotide‐binding protein of bovine‐neutrophil membranes [PDF]

, 1987
Peter Gierschik, Dimitrios N. Sidiropoulos, Allen M. Spiegel, Karl H. Jakobs   +3 more
openalex   +1 more source

Comprehensive αβ T‐Cell Receptor Repertoire Analysis Reveals a Unique CD8+ TCR Landscape in DOCK8‐Deficient Patients

Allergy, EarlyView.
T cell receptor repertoire analysis by high‐throughput immune repertoire RNA‐sequencing in the patients with DOCK8 deficiency. Comprehensive comparisons revealed a restricted TCR repertoire diversity in the patients. Additional assessments showed potential auto‐reactive CD8+ T cell clones in the patients.Abbreviations: DOCK8, dedicator of cytokinesis ...
Ceren Bozkurt, Gökhan Cildir, Umran Aba, Rahmi Kutay Erdogan, Nicholas I Warnock I, Chung Hoow Kok, Asena Pinar Sefer, Sule Haskologlu, Sidem Didar Tekeoglu, Gülşah Merve Kılınç, Canberk Ipsir, Tugba Arikoglu, Aylin Kont Ozhan, Saliha Esenboga, Ahmet Özen, Elif Karakoç‐Aydiner, Sevgi Bilgiç Eltan, Çigdem Aydogmus, Candan Islamoglu, Kübra Baskın, Betul Karaatmaca, Ayse Metin, Deniz Çagdaş, Figen Dogu, Aydan Ikinciogullari, Safa Baris, Baran Erman   +26 more
wiley   +1 more source