Results 221 to 230 of about 104,742 (325)

2'-hydroxyl modification improves enzymatic and thermal stability of mRNA. [PDF]

Mol Ther Nucleic Acids
Uchida S.
europepmc   +1 more source

Pleckstrin Homology Domain-mediated Activation of the Rho-specific Guanine Nucleotide Exchange Factor Dbs by Rac1 [PDF]

, 2004
Li Cheng, Gwendolyn M. Mahon, Elena V. Kostenko, Ian P. Whitehead   +3 more
openalex   +1 more source

A multi‐omics investigation of sarcopenia and frailty: Integrating genomic, epigenomic and telomere length data

Experimental Physiology, EarlyView.
Abstract Sarcopenia and frailty are complex geriatric syndromes influenced by a combination of genetic and environmental factors. Recent studies suggest that specific genetic variants, DNA methylation patterns and shortened telomeres are associated with age‐related diseases and might contribute to the development of both sarcopenia and frailty. In this
Valentina Ginevičienė, Erinija Pranckevičienė, Alina Urnikytė, Laura Jurkūnaitė, Kristijona Gutauskaitė, Rūta Dadelienė, Justina Kilaitė, Ieva Eglė Jamontaitė, Asta Mastavičiūtė, Ildus I. Ahmetov, Vidmantas Alekna   +10 more
wiley   +1 more source

Metabolic Origin, Role and Fate of the Denaturant Guanidine. [PDF]

Microb Biotechnol
Danchin A, de Lorenzo V, Nikel PI, You C.   +3 more
europepmc   +1 more source

The RhoA guanine exchange factor ABR: a glucose‐sensitive mediator of actin reorganization in feto‐placental arterial endothelial cells altered by gestational diabetes mellitus

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of proposed relationship between hyperglycaemia, gestational diabetes mellitus (GDM), active BCR‐related (ABR), RhoA and actin organization of feto‐placental arterial endothelial cells (fpEC). Hyperglycaemia upregulates ABR, which in turn increases RhoA activation.
Silvija Tokic, Boris Novakovic, Barbara Leopold‐Posch, Magdalena Mühlberger, Denise Hoch, Jelena Lögl, Eva M. Bernhart, Richard Saffery, Gernot Desoye, Ursula Hiden   +9 more
wiley   +1 more source

Guanine nucleotide exchange factor GEF115 specifically mediates activation of Rho and serum response factor by the G protein α subunit Gα13

, 1998
Junhao Mao, Huidong Yuan, Wei Xie, Dianqing Wu   +3 more
openalex   +2 more sources

Hypoxia and the cytoskeleton

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley   +1 more source

Understanding the Fidelity and Specificity of DNA Polymerase I. [PDF]

ACS Omega
Miller BR, Yeager AV, Collins JA, Beane A, Blake A, Tate E, Parish CA, Wu EY.   +7 more
europepmc   +1 more source

Long‐term impact of stressful life events on breast cancer risk: A 36‐year genetically informed prospective study in the Finnish Twin Cohort

International Journal of Cancer, Volume 158, Issue 6, Page 1489-1497, 15 March 2026.
What's new? Breast cancer results from a combination of genetic and environmental causes, and the cumulative effect of stressful life events may be a contributing factor. Here, the authors analyzed data from cohort and twin‐pair studies including 36 years of follow‐up to find out how stressful life events affect breast cancer risk. They found that even
Elissar Azzi, Hannes Bode, Teemu Palviainen, Mikaela Hukkanen, Miina Ollikainen, Jaakko Kaprio   +5 more
wiley   +1 more source

High‐Efficiency Genome Editing of Chlorella sp. by CRISPR/Cas9

Plant Biotechnology Journal, EarlyView.
Xinyu Cui, Yi Xin, Yuan Xiao, Bixin Zhang, Qinhua Gan, Yandu Lu   +5 more
wiley   +1 more source