Results 261 to 270 of about 104,742 (325)

Redox response feature and mechanism of Arf1 and their implications for those of Ras and Rho GTPases. [PDF]

J Biol Chem
Johnson HE, Banks EL, Ozuna OS, Heo J.
europepmc   +1 more source

Allosteric determinants in guanine nucleotide-binding proteins

, 2003
Mark E. Hatley, Steve W. Lockless, Scott K. Gibson, Alfred G. Gilman, Rama Ranganathan   +4 more
openalex   +1 more source

Lifespan‐Extending Endogenous Metabolites

Aging Cell, Volume 25, Issue 2, February 2026.
Endogenous metabolites act as mediators of longevity by modulating conserved cellular pathways. We summarize mechanistic evidence linking specific metabolites to lifespan and healthspan benefits across model systems, with discussion of clinical evidence, translational opportunities, and remaining knowledge gaps.
Yizhou Jiang, Jing‐Dong J. Han
wiley   +1 more source

Strain and Sex Variability in Liver, Kidney and Lung Levels of DNA Adducts EB-GII and <i>bis</i>-N7G-BD Following Inhalation Exposure to 1,3-Butadiene in Collaborative Cross Mice. [PDF]

Toxics
Moran E, Goodman S, Wright FA, Evans R, Tretyakova NY, Rusyn I.   +5 more
europepmc   +1 more source

β-PIX-d, a Member of the ARHGEF7 Guanine Nucleotide Exchange Factor Family, Activates Rac1 and Induces Neuritogenesis in Primary Cortical Neurons

Seunghyuk Kim, Heeyoung Park, Jieun Kang, Seung‐Hyuk Choi, Ali Sadra, Sung‐Oh Huh   +5 more
openalex   +2 more sources

A Scalable Organoid Model of Urothelial Aging for Metabolic Interrogation, Infection Modeling, and Reversal of Age‐Associated Changes

Aging Cell, Volume 25, Issue 2, February 2026.
mBEDOs: a scalable platform for modeling urothelial aging. mBEDOs derived from aged mouse bladders capture essential molecular and cellular features of urothelial aging and provide a versatile system for high‐throughput metabolic profiling, therapeutic screening via metabolite supplementation, age‐ and sex‐based analyses, infection modeling, and immune–
Adwaita R. Parab, Arnold M. Salazar, Steven J. Bark, Margarita Divenko, Vasanta Putluri, D'Feau J. Lieu, Aadya S. Singh, Nagireddy Putluri, Indira U. Mysorekar   +8 more
wiley   +1 more source

High tide or low tide: the transport and metabolism of mitochondrial nucleotides. [PDF]

Biochem J
MacVicar T.
europepmc   +1 more source

Genetic Determinants of Hematopoietic Toxicity Risk in Thai Pediatric Patients Undergoing 6‐Mercaptopurine Treatment

Clinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT The nucleoside diphosphate‐linked moiety X‐type motif 15 (NUDT15) has been identified as a key genetic determinant of 6‐mercaptopurine (6‐MP)‐induced hematopoietic toxicity in populations with a high frequency of NUDT15 variants but a low frequency of thiopurine S‐methyltransferase (TPMT) variants.
Kanyarat Khaeso, Su‐on Chainansamit, Pitchayanan Kuwatjanakul, Patcharee Komvilaisak, Nontaya Nakkam, Kunanya Suwannaying, Suda Vannaprasaht, Areerat Dornsena, Wichittra Tassaneeyakul   +8 more
wiley   +1 more source

The Influence of the Capping Step During Solid-Phase Phosphoramidite Synthesis of Oligonucleotides on Synthetic Errors in Oligonucleotides. [PDF]

Molecules
Yakovleva KI, Pereverzev IM, Kechin AA, Boyarskikh UA, Filipenko ML, Shevelev GY, Sherstyuk YV, Dovydenko IS.   +7 more
europepmc   +1 more source

Isolation, identification, and pathogenic potential of Bacillus cereus from diseased big‐belly seahorse Hippocampus abdominalis

Journal of the World Aquaculture Society, Volume 57, Issue 1, February 2026.
Abstract Members of Bacillus cereus have been documented as important bacterial pathogens in aquaculture. However, scarce information is available on B. cereus isolates as causal pathogens of big‐belly seahorses Hippocampus abdominalis. In the present study, a B. cereus isolate (SH1), recovered from a disease outbreak on a seahorse farm, was identified
Chunlei Gai, Chenhao Teng, Yueqi Yang, Yiyao Liu, Haijing Jie, Youhong Wang, Haibin Ye, Haipeng Cao   +7 more
wiley   +1 more source