An Information Theoretical Analysis of Kinase Activated Phosphorylation Dephosphorylation Cycle [PDF]
IEEE Transactions on NanoBioscience, Volume 11, Issue 3, pp. 289 -
295 (2012), 2011 Signal transduction, the information processing mechanism in biological cells, is carried out by a network of biochemical reactions. The dynamics of driven biochemical reactions can be studied in terms of nonequilibrium statistical physics. Such systems may also be studied in terms of Shannon's information theory.
arxiv +1 more source
Impaired desensitization of a human polymorphic α2B-adrenergic receptor variant enhances its sympatho-inhibitory activity in chromaffin cells [PDF]
, 2011 Background α2-adrenergic receptors (ARs) mediate many cellular actions of epinephrine and norepinephrine and inhibit their secretion from adrenal chromaffin cells.
Kassimatis, Theodoros +2 more
core +3 more sources
Reduction of Muscarinic Receptor Density and of Guanine Nucleotide-Stimulated Phosphoinositide Hydrolysis in Human SH-SY5Y Neuroblastoma Cells Following Long-Term Treatment with 12- O -Tetradecanoylphorbol 13-Acetate or Mezerein [PDF]
, 1990 The actions of tumor promoters on the coupling of muscarinic receptors to the hydrolysis of inositol lipids and the generation of Ca 2+ signals were examined in the human neuroblastoma SH-SY5Y cell line.
Cioffi, Catherine L., Fisher, Stephen K.
core +1 more source
Isotype-specific activation of cystic fibrosis transmembrane conductance regulator-chloride channels by cGMP-dependent protein kinase II [PDF]
, 1995 Type II cGMP-dependent protein kinase (cGKII) isolated from pig intestinal brush borders and type I alpha cGK (cGKI) purified from bovine lung were compared for their ability to activate the cystic fibrosis transmembrane conductance ...
Bijman, J. (Jan) +7 more
core +2 more sources
Coupling Efficacy and Selectivity of the Human Μ-Opioid Receptor Expressed as Receptor—GΑ Fusion Proteins in Escherichia coli [PDF]
, 2000 Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/65628/1/j.1471-4159.2000.0751190.x ...
Alt +39 more
core +1 more source
The G alpha q and G alpha 11 proteins couple the thyrotropin-releasing hormone receptor to phospholipase C in GH3 rat pituitary cells [PDF]
, 1992 Thyrotropin-releasing hormone stimulates the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) in GH3 cell membranes. The stimulation of the phosphoinositide phospholipase C (PI/PLC) activity can be blocked by incubation of GH3 membranes with ...
Aragay, Anna M. +2 more
core
Large-Scale Discovery of ERK2 Substrates Identifies ERK-Mediated Transcriptional Regulation by ETV3 [PDF]
, 2011 The mitogen-activated protein kinase (MAPK) extracellular signal–regulated kinase 2 (ERK2) is ubiquitously expressed in mammalian tissues and is involved in a wide range of biological processes.
Carlson, Scott M. +6 more
core +1 more source
On the Gating Mechanisms of the Light-dependent Conductance in Pecten Hyperpolarizing Photoreceptors: Does Light Remove Inactivation in Voltage-dependent K Channels? [PDF]
, 2005 The hyperpolarizing receptor potential of ciliary photoreceptors of scallop and other mollusks is mediated by a cGMP-activated K conductance; these cells also express a transient potassium current triggered by depolarization.
del Pilar Gomez, Maria, Nasi, Enrico
core +2 more sources
ATP-independent Control of Vac8 Palmitoylation by a SNARE Subcomplex on Yeast Vacuoles [PDF]
, 2005 Yeast vacuole fusion requires palmitoylated Vac8. We previously showed that Vac8 acylation occurs early in the fusion reaction, is blocked by antibodies against Sec18 (yeast N-ethylmaleimide-sensitive fusion protein (NSF)), and is mediated by the R-SNARE
Cristodero, Marina +5 more
core +1 more source
Prostaglandin receptors and role of G protein-activated pathways on corpora lutea of pseudopregnant rabbit in vitro [PDF]
, 2001 Studies were conducted to characterize receptors for prostaglandin (PG) F(2alpha) (PGF(2alpha)) and PGE(2), and the signalling pathways regulating total nitric oxide synthase activity and progesterone production in rabbit corpora lutea (CL) of different ...
BOITI C +4 more
core +1 more source