Results 11 to 20 of about 1,634 (145)
Mini Bubble Columns for Miniaturizing Scale‐Down [PDF]
Engineering in Life SciencesThe successful scale‐up of biotechnological processes from laboratory to industrial scale is crucial for translating innovation to practice. Scale‐down simulators have emerged as indispensable tools in this endeavor, enabling the evaluation of potential ...
Moritz Wild, Ralf Takors
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The two PPX-GppA homologues from Mycobacterium tuberculosis have distinct biochemical activities. [PDF]
PLoS ONE, 2012 Inorganic polyphosphate (poly-P), guanosine pentaphosphate (pppGpp) and guanosine tetraphosphate (ppGpp) are ubiquitous in bacteria. These molecules play a variety of important physiological roles associated with stress resistance, persistence, and ...
Mei Y Choi +7 more
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New Phytologist, Volume 237, Issue 4, Page 1086-1099, February 2023., 2023 Summary The nucleotides guanosine tetraphosphate and guanosine pentaphosphate (together (p)ppGpp) are found in a wide range of prokaryotic and eukaryotic organisms where they are associated with stress signalling. In this review, we will discuss recent research highlighting the role of (p)ppGpp signalling as a conserved regulator of photosynthetic ...
Marwa Mehrez, Shanna Romand, Ben Field
wiley +2 more sources
Ribosomal synthesis of guanosine tetra- and pentaphosphate with mRNAs of different chain length [PDF]
FEBS Letters, 1977 V A Erdmann
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NirD curtails the stringent response by inhibiting RelA activity in Escherichia coli
eLife, 2021 Bacteria regulate their metabolism to adapt and survive adverse conditions, in particular to stressful downshifts in nutrient availability. These shifts trigger the so-called stringent response, coordinated by the signaling molecules guanosine tetra and ...
Loïc Léger +4 more
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ppGpp Controls Global Gene Expression in Light and in Darkness in S. elongatus
Cell Reports, 2017 The bacterial and plant stringent response involves production of the signaling molecules guanosine tetraphosphate and guanosine pentaphosphate ((p)ppGpp), leading to global reorganization of gene expression.
Anna M. Puszynska, Erin K. O’Shea
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PLoS Pathogens, 2021 Bacteria inhabit diverse environmental niches and consequently must modulate their metabolism to adapt to stress. The nucleotide second messengers guanosine tetraphosphate (ppGpp) and guanosine pentaphosphate (pppGpp) (collectively referred to as (p ...
N Y Elizabeth Chau +3 more
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Guanosine pentaphosphate phosphohydrolase of Escherichia coli is a long-chain exopolyphosphatase. [PDF]
Proc Natl Acad Sci U S A, 1993 An exopolyphosphatase [exopoly(P)ase; EC 3.6.1.11] activity has recently been purified to homogeneity from a mutant strain of Escherichia coli which lacks the principal exopoly(P)ase. The second exopoly(P)ase has now been identified as guanosine pentaphosphate phosphohydrolase (GPP; EC 3.6.1.40) by three lines of evidence: (i) the sequences of five ...
Keasling JD, Bertsch L, Kornberg A.
europepmc +4 more sources
Regulation of bacterial stringent response by an evolutionarily conserved ribosomal protein L11 methylation [PDF]
mBioLysine and arginine methylation is an important regulator of enzyme activity and transcription in eukaryotes. However, little is known about this covalent modification in bacteria. In this work, we investigated the role of methylation in bacteria.
Hanna E. Walukiewicz +11 more
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Guanosine tetra- and pentaphosphate synthase activity in chloroplasts of a higher plant: association with 70S ribosomes and inhibition by tetracycline [PDF]
Nucleic Acids Research, 2004 Chloroplasts possess bacterial-type systems for transcription and translation. On the basis of the identification of a Chlamydomonas reinhardtii gene encoding a RelA-SpoT homolog (RSH) that catalyzes the synthesis of guanosine tetra- or pentaphosphate [(p)ppGpp], we have previously suggested the operation of stringent control in the chloroplast genetic
Koji Kasai, Kyo Wakasa, Yuzuru Tozawa
exaly +3 more sources