Guinea pigs sublethally infected with aerosolized Legionella pneumophila develop humoral and cell-mediated immune responses and are protected against lethal aerosol challenge. A model for studying host defense against lung infections caused by intracellular pathogens. [PDF]
, 1987 We have employed the guinea pig model of L. pneumophila infection, which mimics Legionnaires' disease in humans both clinically and pathologically, to study humoral and cell-mediated immune responses to L.
Breiman, RF, Horwitz, MA
core
Multicargo Porous Cochlear Electrode Coating for Antifibrosis After Cochlear Implantation
Advanced Science, EarlyView.This study presents a novel porous drug‐loading coating for cochlear electrodes, utilizing MA‐PDMS infused with GelMA hydrogel containing dexamethasone and MXene nanoparticles. The coating enhances biocompatibility, enables sustained drug release, reduces fibrosis, and preserves residual hearing post‐CI.
Lei Ren +15 more
wiley +1 more source
Tissue distribution of cholesterol feedback control in the guinea pig.
Journal of Lipid Research, 1975 The level of cholesterol synthesis and the activity of the cholesterol feedback system were studied in tissue slices from a number of organs of the guinea pig.
A Swann, M H Wiley, M D Siperstein
doaj
Guinea pig model for evaluating the potential public health risk of swine and avian influenza viruses. [PDF]
PLoS ONE, 2010 BACKGROUND: The influenza viruses circulating in animals sporadically transmit to humans and pose pandemic threats. Animal models to evaluate the potential public health risk potential of these viruses are needed.
Yipeng Sun +12 more
doaj +1 more source
Microorganisms, 2022 Salmonella enterica subsp. enterica serovar Typhimurium (S. Typhimurium) is one of the most important foodborne pathogens that infect humans globally.
Dennis E. Carhuaricra Huaman +6 more
doaj +1 more source
Advanced Science, EarlyView.Novel carbon‐11 labeled pyrimidine derivatives are developed as PET imaging probes for visualizing sigma‐1 receptors in the brain. [11C]CNY‐01 demonstrates superior brain uptake and binding specificity in both rodents and non‐human primates. The study reveals decreased sigma‐1 receptor expression in Alzheimer's disease, offering a promising tool for ...
Ping Bai +12 more
wiley +1 more source
C-Kit expression in the gallbladder of guinea pig with chronic calculous cholecystitis and the effect of Artemisia capillaris Thunb on interstitial cells of Cajal [PDF]
Iranian Journal of Basic Medical Sciences, 2016 Objective(s): To study the c-Kit expression in the gallbladder of cholesterol lithogenic guinea pig model and the effect of Artemisia capillaris Thunb on interstitial cells of Cajal (ICCs).
Hua Feng, Fang Wang, Changmiao Wang
doaj
$\mathrm{e}^+$$\mathrm{e}^-$ Beam-beam Parameter Study for a TeV-scale PWFA Linear Collider [PDF]
arXiv, 2020 We perform a beam-beam parameter study for a TeV-scale PWFA (particle-driven plasma wakefield acceleration) $\mathrm{e}^+$$\mathrm{e}^-$ linear collider using GUINEA-PIG simulations. The study shows that the total luminosity follows the $1/\sqrt{\sigma_z}$-scaling predicted by beamstrahlung theory, where $\sigma_z$ is the rms beam length, which is ...
arxiv
, 2009 This chapter deals with the health and medical care issues of guinea pigs. Guinea pigs have wide bodies with short limbs. They have a short, flat nose, laterally placed eyes, and hairless external pinnae. The dentition of the guinea pig is described as aradicular hypsodont.
openaire +2 more sources
Advanced Science, EarlyView.New research reveals that oxytocin signaling during the early postnatal period is critical for regulating brain development and social behavior. Selectively suppressing oxytocin neurons by chemogenetic method shows that early—but not late—disruption leads to autism‐like behaviors.
Zi‐Hui Wang +10 more
wiley +1 more source