Results 11 to 20 of about 172,085 (298)

Th17 Cytokines and the Gut Mucosal Barrier [PDF]

Journal of Clinical Immunology, 2010
Local immune responses serve to contain infections by pathogens to the gut while preventing pathogen dissemination to systemic sites. Several subsets of T cells in the gut (T-helper 17 cells, gammadelta T cells, natural killer (NK), and NK-T cells) contribute to the mucosal response to pathogens by secreting a subset of cytokines including interleukin (
Blaschitz, Christoph, Raffatellu, Manuela   +1 more
openaire   +5 more sources

Effects of Anti-Cytokine Antibodies on Gut Barrier Function

Mediators of Inflammation, 2019
Anti-cytokine antibodies are used in treating chronic inflammatory diseases and autoimmune diseases such as inflammatory bowel disease and rheumatic diseases.
Fang Liu, Seul A. Lee, Stephen M. Riordan, Li Zhang, Lixin Zhu   +4 more
doaj   +2 more sources

Gut Barrier and Microbiota in Cirrhosis [PDF]

Journal of Clinical and Experimental Hepatology, 2022
Gut microbiota and their homeostatic functions are central to the maintenance of the intestinal mucosal barrier. The gut barrier functions as a structural, biological, and immunological barrier, preventing local and systemic invasion and inflammation of pathogenic taxa, resulting in the propagation or causation of organ-specific (liver disease) or ...
Cyriac A. Philips, Philip Augustine
openaire   +2 more sources

Gut barrier in health and disease: focus on childhood.

European review for medical and pharmacological sciences, 2015
The gut barrier is a functional unit, organized as a multi-layer system, made up of two main components: a physical barrier surface, which prevents bacterial adhesion and regulates paracellular diffusion to the host tissues, and a deep functional barrier, that is able to discriminate between pathogens and commensal microorganisms, organizing the immune
Viggiano, D, Ianiro, G, Vanella, G, Bibbò, S, Bruno, G, Simeone, G, Mele, G   +6 more
core   +5 more sources

Gut barrier function in malnourished patients [PDF]

Gut, 1998
Background —The integrity of the gastrointestinal mucosa is a key element in preventing systemic absorption of enteric toxins and bacteria. In the critically ill, breakdown of gut barrier function may fuel sepsis.
F K, Welsh, S M, Farmery, K, MacLennan, M B, Sheridan, G R, Barclay, P J, Guillou, J V, Reynolds   +6 more
openaire   +2 more sources

Understanding the role of the gut in undernutrition: what can technology tell us? [PDF]

, 2021
Gut function remains largely under-investigated in undernutrition, despite its critical role in essential nutrient digestion, absorption and assimilation.
Preston, Tom, Frost, Gary, On behalf of the HUNGer Consortium, Thompson, Alexander, Thompson, A, Preston, T, Shivakumar, Nirupama, Morrison, Douglas J., Edwards, C, Bourke, Claire, Holmes, Elaine, Frost, G, Robertson, Ruairi, Thompson, Alex J., Robertson, Ruairi C., Gary, Frost, Edwards, Christine, Paul, Kelly, Roberston, R, Douglas, Morrison, Bourke, C, Kelly, M, Shivakumar, N, Bourke, Claire D., Kelly, Paul, Holmes, E, Morrison, D   +26 more
core   +1 more source

Dietary calcium decreases but short-chain fructo-oligosaccharides increase colonic permeability in rats [PDF]

, 2010
An increased intestinal permeability is associated with several diseases. Nutrition can influence gut permeability. Previously, we showed that dietary Ca decreases whereas dietary short-chain fructo-oligosaccharides (scFOS) increase intestinal ...
Schepens, M.A.A., Schepens, Marloes A. A.,, Bovee-Oudenhoven, I.M.J., Brummer, R.J.M., Willemsen, Linette E. M.,, Rijnierse, A., Bovee-Oudenhoven, Ingeborg M. J.,, Schonewille, A.J., Vink, C., Arjan J. Schonewille, Rijnierse, Anneke,, Willemsen, L.E.M., Anneke Rijnierse, Carolien Vink, Marloes A. A. Schepens, Meer, R., van de, Willemsen, L. E., Linette E. M. Willemsen, Vink, Carolien,, Bovee Oudenhoven, I.M., Brummer, R.J., Brummer, Robert,, Roelof van der Meer, van der Meer, Roelof,, van der Meer, R., Ingeborg M. J. Bovee-Oudenhoven, van de Meer, R., Robert-Jan M. Brummer, Schonewille, Arjan J.,   +28 more
core   +1 more source

Metabolic adaptation to a high-fat diet is associated with a change in the gut microbiota [PDF]

, 2011
Objective The gut microbiota, which is considered a causal factor in metabolic diseases as shown best in animals, is under the dual influence of the host genome and nutritional environment. This study investigated whether the gut microbiota per se, aside
Klopp, Christophe, Amar, Jacques, Aurelie Waget, Baylac, Audrey, Waget, Aurélie, Klopp, Pascale, Theodorou, Vassilia, Elodie Luche, Iacovoni, Jason, Francoise Ouarné, Bouloumié, Anne, Jerome Mariette, Pascale Klopp, Klopp, Christophe,, Bergé, Mathieu, Mariette, Jérôme, J., Klopp, Pascal, Remy Burcelin, Serino, Matteo, Burcelin, Rémy, Valet, Philippe, Roques, Christine, Bouchez, Olivier, Matteo Serino, Mathieu Bergé, Jacques Amar, Claire Cenac, Philippe Valet, Monsan, Pierre, Jerome Lluch, Sandra Gres, Mariette, Jérôme,, Christophe Klopp, Christine Roques, Pierre Monsan, Mariette, Jérôme, Jason Iacovoni, Vassilia Théodorou, Cenac, Claire, Lluch, Jérôme, Audrey Baylac, Gres, Sandra, Ouarné, Françoise, Anne Bouloumié, Luche, Elodie, Olivier Bouchez   +45 more
core   +1 more source

Elevated faecal ovotransferrin concentrations are indicative for intestinal barrier failure in broiler chickens

Veterinary Research, 2018
Intestinal health is critically important for the welfare and performance of poultry. Enteric diseases that cause gut barrier failure result in high economic losses.
Evy Goossens, Griet Debyser, Chana Callens, Maarten De Gussem, Annelike Dedeurwaerder, Bart Devreese, Freddy Haesebrouck, Monika Flügel, Stefan Pelzer, Frank Thiemann, Richard Ducatelle, Filip Van Immerseel   +11 more
doaj   +1 more source

Gut microbiota-derived 3-phenylpropionic acid promotes intestinal epithelial barrier function via AhR signaling

Microbiome, 2023
Background The intestinal epithelial barrier confers protection against the intestinal invasion by pathogens and exposure to food antigens and toxins. Growing studies have linked the gut microbiota to the intestinal epithelial barrier function.
Jun Hu, Jianwei Chen, Xiaojian Xu, Qiliang Hou, Jing Ren, Xianghua Yan   +5 more
doaj   +1 more source