Results 11 to 20 of about 160,336 (258)
Gut Barrier and Microbiota in Cirrhosis [PDF]
Journal of Clinical and Experimental Hepatology, 2022 Gut microbiota and their homeostatic functions are central to the maintenance of the intestinal mucosal barrier. The gut barrier functions as a structural, biological, and immunological barrier, preventing local and systemic invasion and inflammation of pathogenic taxa, resulting in the propagation or causation of organ-specific (liver disease) or ...
Cyriac A. Philips, Philip Augustine
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Gut barrier function in malnourished patients [PDF]
Gut, 1998 Background —The integrity of the gastrointestinal mucosa is a key element in preventing systemic absorption of enteric toxins and bacteria. In the critically ill, breakdown of gut barrier function may fuel sepsis.
F K, Welsh +6 more
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Th17 Cytokines and the Gut Mucosal Barrier [PDF]
Journal of Clinical Immunology, 2010 Local immune responses serve to contain infections by pathogens to the gut while preventing pathogen dissemination to systemic sites. Several subsets of T cells in the gut (T-helper 17 cells, gammadelta T cells, natural killer (NK), and NK-T cells) contribute to the mucosal response to pathogens by secreting a subset of cytokines including interleukin (
Blaschitz, Christoph +1 more
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Veterinary Research, 2018 Intestinal health is critically important for the welfare and performance of poultry. Enteric diseases that cause gut barrier failure result in high economic losses.
Evy Goossens +11 more
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Microbiome, 2023 Background The intestinal epithelial barrier confers protection against the intestinal invasion by pathogens and exposure to food antigens and toxins. Growing studies have linked the gut microbiota to the intestinal epithelial barrier function.
Jun Hu +5 more
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Gut barrier function and the surgeon
Journal of British Surgery, 1990 Abstract There is accumulating evidence that multiple organ failure is not always the result of an established septic focus. Increasing attention has centred on the gut as a reservoir of bacteria (and bacterial endotoxins) that can traverse the intestinal mucosal barrier (a process called ‘bacterial translocation’) and initiate the ...
R, Saadia +3 more
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Gut-Brain Connection: Microbiome, Gut Barrier, and Environmental Sensors
Immune Network, 2021 The gut is an important organ with digestive and immune regulatory function which consistently harbors microbiome ecosystem. The gut microbiome cooperates with the host to regulate the development and function of the immune, metabolic, and nervous systems.
Min-Gyu Gwak, Sun-Young Chang
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The Role of Gut Barrier Dysfunction and Microbiome Dysbiosis in Colorectal Cancer Development
Frontiers in Oncology, 2021 Accumulating evidence indicates that breakdown of the+ protective mucosal barrier of the gut plays a role in colorectal cancer (CRC) development. Inflammation and oxidative stress in the colonic epithelium are thought to be involved in colorectal ...
Flavia Genua +4 more
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Roles and regulation of the mucus barrier in the gut [PDF]
Tissue Barriers, 2015 The gastrointestinal tract is coated by a thick layer of mucus that forms the front line of innate host defense. Mucus consists of high molecular weight glycoproteins called mucins that are synthesized and secreted by goblet cells and functions primarily to lubricate the epithelium and protect it from damage by noxious substances.
Steve, Cornick +2 more
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Leaky Gut in IBD: Intestinal Barrier–Gut Microbiota Interaction
Journal of Microbiology and Biotechnology, 2022 Inflammatory bowel disease (IBD) is a global disease that is in increasing incidence. The gut, which contains the largest amount of lymphoid tissue in the human body, as well as a wide range of nervous system components, is integral in ensuring intestinal homeostasis and function.
Yu, Shunying +6 more
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