Results 11 to 20 of about 1,115,431 (287)

Gut Barrier and Microbiota in Cirrhosis [PDF]

Journal of Clinical and Experimental Hepatology, 2022
Gut microbiota and their homeostatic functions are central to the maintenance of the intestinal mucosal barrier. The gut barrier functions as a structural, biological, and immunological barrier, preventing local and systemic invasion and inflammation of pathogenic taxa, resulting in the propagation or causation of organ-specific (liver disease) or ...
Cyriac A. Philips, Philip Augustine
openaire   +2 more sources

Bovine colostrum is a health food supplement which prevents NSAID induced gut damage [PDF]

, 1999
BACKGROUNDNon-steroidal anti-inflammatory drugs (NSAIDs) are effective for arthritis but cause gastrointestinal injury. Bovine colostrum is a rich source of growth factors and is marketed as a health food supplement.AIMSTo examine whether spray dried ...
R A Goodlad, Marchbank, T, Johnson, W, D N Floyd, D P Calnan, Floyd, DN, Playford, RJ, T Marchbank, Goodlad, RA, W Johnson, Calnan, DP, R J Playford, R O Adenekan, C E Macdonald, Adenekan, RO, Macdonald, CE   +15 more
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Gut barrier function in malnourished patients [PDF]

Gut, 1998
Background —The integrity of the gastrointestinal mucosa is a key element in preventing systemic absorption of enteric toxins and bacteria. In the critically ill, breakdown of gut barrier function may fuel sepsis.
F K, Welsh, S M, Farmery, K, MacLennan, M B, Sheridan, G R, Barclay, P J, Guillou, J V, Reynolds   +6 more
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The stress polarity signaling (SPS) pathway serves as a marker and a target in the leaky gut barrier: implications in aging and cancer

Life Science Alliance, 2020
Using patient-derived organoids the authors show how a specialized polarity pathway protects our gut barrier from stress-induced collapse. Findings highlight both diagnostic and therapeutic potential of the pathway for treating gut barrier dysfunction in
Pradipta Ghosh, Lee Swanson, Ibrahim M Sayed, Yash Mittal, Blaze B Lim, Stella-Rita Ibeawuchi, Marc Foretz, Benoit Viollet, Debashis Sahoo, Soumita Das   +9 more
doaj   +1 more source

Th17 Cytokines and the Gut Mucosal Barrier [PDF]

Journal of Clinical Immunology, 2010
Local immune responses serve to contain infections by pathogens to the gut while preventing pathogen dissemination to systemic sites. Several subsets of T cells in the gut (T-helper 17 cells, gammadelta T cells, natural killer (NK), and NK-T cells) contribute to the mucosal response to pathogens by secreting a subset of cytokines including interleukin (
Blaschitz, Christoph, Raffatellu, Manuela   +1 more
openaire   +4 more sources

Gut microbiota-derived 3-phenylpropionic acid promotes intestinal epithelial barrier function via AhR signaling

Microbiome, 2023
Background The intestinal epithelial barrier confers protection against the intestinal invasion by pathogens and exposure to food antigens and toxins. Growing studies have linked the gut microbiota to the intestinal epithelial barrier function.
Jun Hu, Jianwei Chen, Xiaojian Xu, Qiliang Hou, Jing Ren, Xianghua Yan   +5 more
doaj   +1 more source

Dietary calcium decreases but short-chain fructo-oligosaccharides increase colonic permeability in rats [PDF]

, 2010
An increased intestinal permeability is associated with several diseases. Nutrition can influence gut permeability. Previously, we showed that dietary Ca decreases whereas dietary short-chain fructo-oligosaccharides (scFOS) increase intestinal ...
Schepens, M.A.A., Schepens, Marloes A. A.,, Bovee-Oudenhoven, I.M.J., Brummer, R.J.M., Willemsen, Linette E. M.,, Rijnierse, A., Bovee-Oudenhoven, Ingeborg M. J.,, Schonewille, A.J., Vink, C., Arjan J. Schonewille, Rijnierse, Anneke,, Willemsen, L.E.M., Anneke Rijnierse, Carolien Vink, Marloes A. A. Schepens, Meer, R., van de, Willemsen, L. E., Linette E. M. Willemsen, Vink, Carolien,, Bovee Oudenhoven, I.M., Brummer, R.J., Brummer, Robert,, Roelof van der Meer, van der Meer, Roelof,, van der Meer, R., Ingeborg M. J. Bovee-Oudenhoven, van de Meer, R., Robert-Jan M. Brummer, Schonewille, Arjan J.,   +28 more
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Metabolic adaptation to a high-fat diet is associated with a change in the gut microbiota [PDF]

, 2011
Objective The gut microbiota, which is considered a causal factor in metabolic diseases as shown best in animals, is under the dual influence of the host genome and nutritional environment. This study investigated whether the gut microbiota per se, aside
Klopp, Christophe, Amar, Jacques, Aurelie Waget, Baylac, Audrey, Waget, Aurélie, Klopp, Pascale, Theodorou, Vassilia, Elodie Luche, Iacovoni, Jason, Francoise Ouarné, Bouloumié, Anne, Jerome Mariette, Pascale Klopp, Klopp, Christophe,, Bergé, Mathieu, Mariette, Jérôme, J., Klopp, Pascal, Remy Burcelin, Serino, Matteo, Burcelin, Rémy, Valet, Philippe, Roques, Christine, Bouchez, Olivier, Matteo Serino, Mathieu Bergé, Jacques Amar, Claire Cenac, Philippe Valet, Monsan, Pierre, Jerome Lluch, Sandra Gres, Mariette, Jérôme,, Christophe Klopp, Christine Roques, Pierre Monsan, Mariette, Jérôme, Jason Iacovoni, Vassilia Théodorou, Cenac, Claire, Lluch, Jérôme, Audrey Baylac, Gres, Sandra, Ouarné, Françoise, Anne Bouloumié, Luche, Elodie, Olivier Bouchez   +45 more
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Gut barrier function and the surgeon

Journal of British Surgery, 1990
Abstract There is accumulating evidence that multiple organ failure is not always the result of an established septic focus. Increasing attention has centred on the gut as a reservoir of bacteria (and bacterial endotoxins) that can traverse the intestinal mucosal barrier (a process called ‘bacterial translocation’) and initiate the ...
R, Saadia, M, Schein, C, MacFarlane, K D, Boffard   +3 more
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Elevated faecal ovotransferrin concentrations are indicative for intestinal barrier failure in broiler chickens

Veterinary Research, 2018
Intestinal health is critically important for the welfare and performance of poultry. Enteric diseases that cause gut barrier failure result in high economic losses.
Evy Goossens, Griet Debyser, Chana Callens, Maarten De Gussem, Annelike Dedeurwaerder, Bart Devreese, Freddy Haesebrouck, Monika Flügel, Stefan Pelzer, Frank Thiemann, Richard Ducatelle, Filip Van Immerseel   +11 more
doaj   +1 more source