Results 21 to 30 of about 12,827,422 (265)

Development of a novel human intestinal model to elucidate the effect of anaerobic commensals on Escherichia coli infection

Disease Models & Mechanisms, 2022
The gut microbiota plays a crucial role in protecting against enteric infection. However, the underlying mechanisms are largely unknown owing to a lack of suitable experimental models.
Conor J. McGrath, Edgaras Laveckis, Andrew Bell, Emmanuelle Crost, Nathalie Juge, Stephanie Schüller   +5 more
doaj   +1 more source

The environment within: how gut microbiota may influence metabolism and body composition [PDF]

, 2010
Obesity, diabetes and consequently atherosclerotic vascular disease have become major health and public health issues worldwide. The increasing and staggering prevalence of obesity might not only be explained by nutritional habits or the reduction of ...
Vos, W.M., de, A. Vrieze, Hoekstra, J. B. L., E. G. Zoetendal, Zoetendal, E.G., F. Holleman, Vrieze, A., W. M. de Vos, J. B. L. Hoekstra, M. Nieuwdorp, Holleman, F., Zoetendal, E. G., Hoekstra, J.B., de Vos, W. M., Nieuwdorp, M.   +14 more
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Impact of Environmental Pollutants on Gut Microbiome and Mental Health via the Gut–Brain Axis

, 2022
Over the last few years, the microbiome has emerged as a high-priority research area to discover missing links between brain health and gut dysbiosis. Emerging evidence suggests that the commensal gut microbiome is an important regulator of the gut–brain
Sarma, Devojit Kumar, Poonam Sharma, Manoj Kumar, Shubham, Swasti, Swasti Shubham, Kumawat, Manoj, Singh, Samradhi, Samradhi Singh, Kumar, Manoj, Devojit Kumar Sarma, Nagpal, Ravinder, Namrata Pal, Sharma, Poonam, Ravinder Nagpal, Pal, Namrata, Manoj Kumawat, Tiwari, Rajnarayan R., Rajnarayan R. Tiwari   +17 more
core   +1 more source

Genomic analysis on broiler-associated Clostridium perfringens strains and exploratory caecal microbiome investigation reveals key factors linked to poultry necrotic enteritis

Animal Microbiome, 2019
Background Clostridium perfringens is a key pathogen in poultry-associated necrotic enteritis (NE). To date there are limited Whole Genome Sequencing based studies describing broiler-associated C. perfringens in healthy and diseased birds.
Raymond Kiu, Joseph Brown, Harley Bedwell, Charlotte Leclaire, Shabhonam Caim, Derek Pickard, Gordon Dougan, Ronald A. Dixon, Lindsay J. Hall   +8 more
doaj   +1 more source

Discovery of intramolecular trans-sialidases in human gut microbiota suggests novel mechanisms of mucosal adaptation [PDF]

, 2015
The authors acknowledge the support of the Biotechnology and Biological Sciences Research Council (BBSRC), this research was partly funded by the BBSRC Institute Strategic Programme for The Gut Health and Food Safety (BB/J004529/1) and by the BB/L008602 ...
Vos, W.M., de, Hardy-Goddard, Jemma, Crost, Emmanuelle H., de Vos, Willem M., Gall, G., Le, Taylor, Garry L., Walshaw, J., Tailford, L.E., Crost, E.H., Taylor, G.L., Juge, N., Owen, C.D., Tailford, Louise E., Owen, C. David, Le Gall, Gwenaelle, Hardy-Goddard, J., Juge, Nathalie, Walshaw, John, Taylor, Garry L.; id_orcid   +18 more
core   +1 more source

N-Acetylcysteine improves intestinal function and attenuates intestinal autophagy in piglets challenged with β-conglycinin

Scientific Reports, 2021
β-Conglycinin (β-CG), an anti-nutritional factor, is a major allergen in soybeans to induce intestinal dysfunction and diarrhea in neonatal animals, including piglets and human infants.
Huiyun Wang, Chengcheng Li, Meng Peng, Lei Wang, Di Zhao, Tao Wu, Dan Yi, Yongqing Hou, Guoyao Wu   +8 more
doaj   +1 more source

The orphan germinant receptor protein GerXAO (but not GerX3b) is essential for L-alanine induced germination in Clostridium botulinum Group II

Scientific Reports, 2018
Clostridium botulinum is an anaerobic spore forming bacterium that produces the potent botulinum neurotoxin that causes a severe and fatal neuro-paralytic disease of humans and animals (botulism). C.
Jason Brunt, Andrew T. Carter, Hannah V. Pye, Michael W. Peck   +3 more
doaj   +1 more source

Analysis of Metabolites in Human Gut: Illuminating the Design of Gut-Targeted Drugs [PDF]

, 2023
Gut-targeted drugs provide a new drug modality besides that of oral, systemic molecules, that could tap from the growing knowledge of gut metabolites of bacterial or host origin and their involvement in biological processes and health through their ...
Andrés, Sánchez-Ruiz, Gonzalo, Colmenarejo, Alberto, Gil-Pichardo   +2 more
core   +1 more source

Special Issue “Gut Microbioma Structure and Functions in Human Health and Disease”: Editorial

, 2023
The human gut microbiota is an integral component of the human body that can strike a delicate balance between health and disease [...
Francesco Di Pierro
core   +1 more source

Effects of N-acetylcysteine on the energy status and antioxidant capacity in heart and liver of cold-stressed broilers [PDF]

Asian-Australasian Journal of Animal Sciences, 2020
Objective Cold stress induces oxidative damage and impairs energy status of broilers. N-acetylcysteine (NAC) exhibits antioxidant properties and modulates energy metabolism of animals.
Chengcheng Li, Meng Peng, Man Liao, Shuangshuang Guo, Yongqing Hou, Binying Ding, Tao Wu, Dan Yi   +7 more
doaj   +1 more source