Results 81 to 90 of about 306,961 (316)

Gut Microbiota Dysbiosis in Functional Dyspepsia

, 2020
Functional dyspepsia (FD) is one of the most prevalent chronic functional gastrointestinal disorders. Several distinct pathophysiological mechanisms, including gastro duodenal motor disorders, visceral hypersensitivity, brain-gut interactions, duodenal ...
Paraskevas Gkolfakis, Ruchi Mathur, Ioannis S. Papanikolaou, Evangelos J. Giamarellos-Bourboulis, Konstantinos Triantafyllou, Georgios Tziatzios, Mark Pimentel   +6 more
core   +1 more source

Intestinal microbiota in human health and disease: the impact of probiotics [PDF]

, 2011
The complex communities of microorganisms that colonise the human gastrointestinal tract play an important role in human health. The development of culture-independent molecular techniques has provided new insights in the composition and diversity of the
Gerritsen, J., Vos, W.M., de, Ger T. Rijkers, Smidt, H., Jacoline Gerritsen, Rijkers, G.T., Willem M. de Vos, Hauke Smidt, de Vos, W.M.   +8 more
core   +1 more source

Gut Microbiota and Respiratory Infections: Insights from Mendelian Randomization

, 2023
The role of the gut microbiota in modulating the risk of respiratory infections has garnered increasing attention. However, conventional clinical trials have faced challenges in establishing the precise relationship between the two.
Jiaqi Li, Xin Wang, Shengyu Huang, Zhihao Zhu, Feng Zhu, Xiaobin Liu, Guangping Yang, Yusong Wang, Qimin Ma, Guanghua Guo, Tuo Shen   +10 more
core   +1 more source

Comprehensive analysis of stearoyl-coenzyme A desaturase in prostate adenocarcinoma: insights into gene expression, immune microenvironment and tumor progression

Frontiers in Immunology
Prostate adenocarcinoma (PRAD) is a prevalent global malignancy which depends more on lipid metabolism for tumor progression compared to other cancer types.
Jie Wang, Liang Ying, He Xiong, Duan-Rui Zhou, Yi-Xuan Wang, Hui-Lian Che, Zhang-Feng Zhong, Guo-Sheng Wu, Yun-Jun Ge   +8 more
doaj   +1 more source

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source

The effect of a multispecies probiotic on the composition of the faecal microbiota and bowel habits in chronic obstructive pulmonary disease patients treated with antibiotics

, 2009
Short-term antibiotic treatment profoundly affects the intestinal microbiota, which may lead to sustained changes in microbiota composition. Probiotics may restore such a disturbance.
Jonkers, D., Rombouts, F.M., Smidt, H., Pennings, H.J., Catherina J. M. Koning, Stockbrugger, R., Wouters, E., Hauke Smidt, Ellen Stobberingh, Daisy Jonkers, Reinhold Stockbrügger, Rombouts, F., Stockbrügger, R.W., Herman-Jan Pennings, Stobberingh, E., Koning, C.J., Frans Rombouts, Emiel Wouters   +17 more
core   +1 more source

Mechanostimulatory Cues Determine Intestinal Fibroblast Fate and Profibrotic Remodeling in a Physiodynamic Human Gut‐on‐a‐Chip

Advanced Science, EarlyView.
A healthy gut barrier shields underlying fibroblasts from luminal shear forces, illustrating that “good fences make good neighbors.” Barrier damage exposes fibroblasts to shear stress, inducing cell death and the emergence of stress‐adapted, profibrotic fibroblasts. Sustained shear exposure promotes the formation of stiff aggregates of mechanoadapative
Soyoun Min, Nam Than, Yong Cheol Shin, Elif G. Ertugral, Chandrasekhar R. Kothapalli, Olumuyiwa Awoniyi, Hyun Jung Kim   +6 more
wiley   +1 more source

Gut Microbiota: In Sickness and in Health [PDF]

Microbial Biotechnology, 2014
Peer ...
Huertas, M. José, Michán, Carmen
openaire   +7 more sources

Targeting Peptostreptococcus anaerobius with an Iron‐Based Nanozyme Reverses Ferroptosis Resistance and Enhances Antitumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao, Jun Wang, Hanwenchen Wang, Xiang Sun, Fang Fang, Shiying Li, Jianping Liu, Changrong Shi, Pengyuan Qi, Jianhua Zou, Xiaoyuan Chen, Kailin Cai   +11 more
wiley   +1 more source

Impact of Gut Microbiota on Host Aggression: Potential Applications for Therapeutic Interventions Early in Development

, 2023
Aggression in the animal kingdom is a necessary component of life; however, certain forms of aggression, especially in humans, are pathological behaviors that are detrimental to society.
Fumiaki Akama, Natsuru Watanabe, Katsunaka Mikami, Keitaro Kimoto, Kenji Yamamoto, Takumi Tochio   +5 more
core   +1 more source