Results 21 to 30 of about 8,960 (210)

A nested case-control study on the association of gut virome in early pregnancy and gestational diabetes mellitus [PDF]

Frontiers in Microbiology
BackgroundRecent studies have increasingly shown the connection between gut microbiome and gestational diabetes mellitus (GDM). However, no studies have explored the relationship between the gut virome and GDM, and the underlying mechanism remains ...
Xinrui Wu, Xinrui Wu, Xinpeng Liu, Wenbo Xu, Wenhui Chen, Zixin Zhong, Hongzhuan Tan, Tianyu Xiang   +7 more
doaj   +2 more sources

The gut virome: A new microbiome component in health and disease

EBioMedicine, 2022
Summary: The human gastrointestinal tract harbours an abundance of viruses, collectively known as the gut virome. The gut virome is highly heterogeneous across populations and is linked to geography, ethnicity, diet, lifestyle, and urbanisation.
Zhirui Cao, Naoki Sugimura, Elke Burgermeister, Matthias P. Ebert, Tao Zuo, Ping Lan   +5 more
doaj   +1 more source

The Gut Virome Database Reveals Age-Dependent Patterns of Virome Diversity in the Human Gut [PDF]

Cell Host & Microbe, 2020
The gut microbiome profoundly affects human health and disease, and their infecting viruses are likely as important, but often missed because of reference database limitations. Here, we (1) built a human Gut Virome Database (GVD) from 2,697 viral particle or microbial metagenomes from 1,986 individuals representing 16 countries, (2) assess its ...
Gregory, Ann C., Zablocki, Olivier, Zayed, Ahmed A., Howell, Allison, Bolduc, Benjamin, Sullivan, Matthew B.   +5 more
openaire   +2 more sources

The human gut virome: composition, colonization, interactions, and impacts on human health

Frontiers in Microbiology, 2023
The gut virome is an incredibly complex part of the gut ecosystem. Gut viruses play a role in many disease states, but it is unknown to what extent the gut virome impacts everyday human health.
Evan Pargin, Michael J. Roach, Amber Skye, Bhavya Papudeshi, Laura K. Inglis, Vijini Mallawaarachchi, Susanna R. Grigson, Clarice Harker, Robert A. Edwards, Sarah K. Giles   +9 more
doaj   +1 more source

Beyond the gut bacterial microbiota: The gut virome [PDF]

Journal of Medical Virology, 2016
The gastrointestinal tract is colonized with a highly different population of bacterial, viral, ad fungal species; viruses are reported to be dominant. The composition of gut virome is closely related to dietary habits and surrounding environment. Host and their intestinal microbes live in a dynamic equilibrium and viruses stimulate a low degree of ...
Columpsi, P, Sacchi, P, Zuccaro, V, Cima, S, Sarda, C, Mariani, M, Gori, A, Bruno, R.   +7 more
openaire   +4 more sources

Emerging Roles of Gut Virome in Pediatric Diseases [PDF]

International Journal of Molecular Sciences, 2021
In the last decade, the widespread application of shotgun metagenomics provided extensive characterization of the bacterial “dark matter” of the gut microbiome, propelling the development of dedicated, standardized bioinformatic pipelines and the systematic collection of metagenomic data into comprehensive databases.
Valerio Fulci, Laura Stronati, Salvatore Cucchiara, Ilaria Laudadio, Claudia Carissimi   +4 more
openaire   +3 more sources

Gut Virome and Inflammatory Bowel Disease [PDF]

Inflammatory Bowel Diseases, 2016
Gut virome has been shown to yield some beneficial effects on humans, being deeply involved in physiology, inflammation, immunity, and disease. Together with transkingdom interactions, it can interplay with genetic variation in the host to establish specific phenotypes. These interactions can lead to phenotypes not observed with either the virus or the
Lopetuso, Loris Riccardo, Ianiro, Gianluca, Scaldaferri, Franco, Cammarota, Giovanni, Gasbarrini, Antonio   +4 more
openaire   +4 more sources

Gut virome profile in healthy Saudi children

Saudi Journal of Gastroenterology, 2023
Background: The role of viruses is well known in health and disease. The aim of this report was to describe the profile of viruses in the gut of healthy Saudi children. Methods: In 20 randomly selected school age children from Riyadh, stool samples were collected in cryovials and ...
Mohammad I. El Mouzan, Asaad A. Assiri, Ahmed A. Al Sarkhy, Mona M. Alasmi   +3 more
openaire   +3 more sources

Prophages are gut virome pioneers [PDF]

Nature Reviews Microbiology, 2020
A recent study shows that assembly of gut viral communities in early life occurs in distinct steps and is modulated by breastfeeding.
openaire   +2 more sources

Crosstalk between the Intestinal Virome and Other Components of the Microbiota, and Its Effect on Intestinal Mucosal Response and Diseases

Journal of Immunology Research, 2022
In recent years, there has been ample evidence illustrating the effect of microbiota on gut immunity, homeostasis, and disease. Most of these studies have engaged more efforts in understanding the role of the bacteriome in gut mucosal immunity and ...
Njinju Asaba Clinton, Sodiq Ayobami Hameed, Eugene Kusi Agyei, Joy Chinwendu Jacob, Victor Oyewale Oyebanji, Cyril Ekabe Jabea   +5 more
doaj   +1 more source