Microfluidic characterization of biomimetic membrane mechanics with an on-chip micropipette
Micro and Nano Engineering, 2020 The mechanic properties of cell membranes control many biological processes. The complexity of natural membranes is often dealt with by building synthetic vesicles (Giant Unilamellar Vesicles, GUVs), which can be thought as micron-sized minimal cells ...
Marianne Elias +9 more
doaj +1 more source
Studies of cationic amphiphilic drug catalysed membrane degradation [PDF]
, 2007 Imperial Users ...
Sebai, Sarra C., Sebai, Sarra C.
core
Hydrophobic gating of mechanosensitive channel of large conductance evidenced by single-subunit resolution [PDF]
, 2012 Mechanosensitive (MS) ion channels are membrane proteins that detect and respond to membrane tension in all branches of life. In bacteria, MS channels prevent cells from lysing upon sudden hypoosmotic shock by opening and releasing solutes and water ...
A. Kocer +30 more
core +2 more sources
Macromolecular Rapid Communications, EarlyView.Diacetylene‐containing glycan mimetics cluster upon selective lectin binding in GUVs. Subsequent irradiation leads to the formation of fluorescent polymer clusters, while non‐clustered glycan mimetics remain unaffected in the membrane. ABSTRACT The glycocalyx, a dense layer of glycoproteins and glycolipids on eukaryotic cells, is essential for cellular
Luca‐Cesare Blawitzki +5 more
wiley +1 more source
Surfactant-free production of biomimetic giant unilamellar vesicles using PDMS-based microfluidics
Communications Chemistry, 2021 The production of giant unilamellar vesicles by microfluidics commonly involves additives, which may interfere with the resultant membrane properties. Here pure lipid GUVs are prepared which exclude residual surfactants and other additives.
Naresh Yandrapalli +3 more
doaj +1 more source
Effects of seaweed sterols fucosterol and desmosterol on lipid membranes [PDF]
, 2017 Higher sterols are universally present in large amounts (20–30%) in the plasma membranes of all eukaryotes whereas they are universally absent in prokaryotes. It is remarkable that each kingdom of the eukaryotes has chosen, during the course of evolution,
Bagatolli, Luis A. +5 more
core +2 more sources
Advances in Elemene Nanodelivery Systems: From Material Design to Disease Treatment
Rare Metals, EarlyView.ABSTRACT Elemene (ELE) is a bioactive sesquiterpenoid extracted from traditional Chinese herbs, demonstrating broad‐spectrum antitumor, anti‐inflammatory, and analgesic properties with significant therapeutic potential. However, its clinical utility is constrained by inherent physicochemical limitations, including volatility and hydrophobicity, which ...
Xiao Wang +9 more
wiley +1 more source
Microfluidic Giant Polymer Vesicles Equipped with Biopores for High‐Throughput Screening of Bacteria
Advanced ScienceUnderstanding the mechanisms of antibiotic resistance is critical for the development of new therapeutics. Traditional methods for testing bacteria are often limited in their efficiency and reusability.
Lukas Heuberger +6 more
doaj +1 more source
The Influence of high pressure on the bending rigidity of model membranes [PDF]
, 2015 Curvature is a fundamental lipid membrane property that influences many membrane-mediated biological processes and dynamic soft materials. One of the key parameters that determines the energetics of curvature change is the membrane bending rigidity ...
Brooks, NJ +3 more
core +2 more sources
Solvent‐Mediated Dewetting Principles for Cell‐Sized Liposome Formation
Small, EarlyView.Dynamics of solvent‐mediated dewetting for giant unilamellar liposome formation. Solvent removal, through changing lipid packing and membrane tension, is shown to induce partial dewetting into equilibrium low and high budding angle morphologies. Complete dewetting requires mechanical force, quantified using optical tweezers.
Mostafa Bakouei +6 more
wiley +1 more source