Results 11 to 20 of about 41,559 (188)

The long non-coding RNA H19 suppresses carcinogenesis and chemoresistance in hepatocellular carcinoma [PDF]

Cell Stress, 2017
The long non-coding RNA (lncRNA) H19 represents a maternally expressed and epigenetically regulated imprinted gene product and is discussed to have either tumor-promoting or tumor-suppressive actions.
Christina S. Schultheiss, Stephan Laggai, Beate Czepukojc, Usama K. Hussein, Markus List, Ahmad Barghash, Sascha Tierling, Kevan Hosseini, Nicole Golob-Schwarzl, Juliane Pokorny, Nina Hachenthal, Marcel Schulz, Volkhard Helms, Jörn Walter, Vincent Zimmer, Frank Lammert, Rainer M. Bohle, Luisa Dandolo, Johannes Haybaeck, Alexandra K. Kiemer, Sonja M. Kessler   +20 more
doaj   +2 more sources

rs217727 of lncRNA H19 is Associated with Cervical Cancer Risk in the Chinese Han Population

Pharmacogenomics and Personalized Medicine, 2023
Jie Dai,1,* Shao Zhang,2,* Yuhan Shi,3 Jinmei Xu,2 Weipeng Liu,1 Jia Yang,1 Li Shi,1 Zhiling Yan,2,4 Chuanyin Li1 1Department of Immunogenetics, Institute of Medical Biology, Chinese Academy of Medical Sciences & Peking Union Medical College ...
Dai J, Zhang S, Shi Y, Xu J, Liu W, Yang J, Shi L, Yan Z, Li C   +8 more
doaj   +1 more source

Long non-coding RNA H19 promotes cervical cancer development via targeting the microRNA-140/ALDH1A1 axis

European Journal of Medical Research
Background Dysregulation of long non-coding RNA H19 (lncRNA H19) is involved in cervical cancer (CC) progression. This study aims to unveil the specific role and relevant mechanism of lncRNA H19 in CC. Methods The expression of lncRNA H19 in CC cells was
Jie Ming, Fang Cheng, Yating Fu, Meng Zhang, Qian Rou, Kaixiong Liu, Zinati Nuertai, Shanshan Xu, Ling Tao, Alfira Abudujapar, Ying Liu   +10 more
doaj   +2 more sources

Preimplantation factor modulates oligodendrocytes by H19-induced demethylation of NCOR2. [PDF]

, 2021
Failed or altered gliogenesis is a major characteristic of diffuse white matter injury in survivors of premature birth. The developmentally regulated long noncoding RNA (lncRNA) H19 inhibits S-adenosylhomocysteine hydrolase (SAHH) and contributes to ...
Hyder, Fahmeed, Barnea, Eytan, Mueller, Martin, Keller, Irene, Haesler, Valérie, Paidas, Michael, Ornaghi, Sara, Spinelli, Marialuigia, Boucard, Céline, Irene, Keller, Bordey, Angelique, Schoeberlein, Andreina, Zhang, Longbo, Coman, Daniel, Surbek, Daniel   +14 more
core   +2 more sources

LncRNA H19 induces immune dysregulation of BMMSCs, at least partly, by inhibiting IL-2 production

Molecular Medicine, 2021
Background Systemic lupus erythematosus (SLE) is a representative systemic autoimmune disease. LncRNA H19 has been identified to participate in various biological processes in human diseases. However, the role of H19 in SLE remains unclear.
Xinpeng Chen, Xiuxia Luo, Yazhi Wei, Hualin Sun, Liping Dai, Yidou Tangzhou, Huijie Jin, Zhihua Yin   +7 more
doaj   +1 more source

Expression of two long noncoding ribonucleic acids (growth arrest-specific 5 and H19) in rheumatoid arthritis patients: Relation to clinical characteristics and disease activity

Indian Journal of Rheumatology, 2021
Background: Rheumatoid arthritis (RA) is a relatively common autoimmune disease in which genetic risk factors are well defined. Genetic studies are promising in exploring the long noncoding ribonucleic acids (lncRNAs): growth arrest-specific 5 (GAS5) and
Gehan Abdel-Fattah Hegazy, Olfat Shaker, Omnia Aly, Hanan Hassan Zaki, Mohamed R Herzalla, Ahmed Fathy Gomaa, Safaa Sayed, Maysa M Haroon   +7 more
doaj   +1 more source

RNA-binding Protein LIN28a Regulates New Myocyte Formation in the Heart via lncRNA-H19

, 2023
 Background: Developmental cardiac tissue holds remarkable capacity to regenerate after injury and consists of regenerative mononuclear and diploid cardiomyocytes (MNDCMs).
Jennifer Pennise (14432220), Tej M. Patel (10106364), Tao Wang (12008), Michael Behanan (14432214), Robert C. Hoy (8807582), Vagner Oliveira-Carvalho Rigaud (12706817), Mohsin Khan (352381), Justin Kurian (4459243), Lindsay Kraus (9013847), Isabella Brosious (14432217), Sadia Mohsin (541545), Steven R. Houser (6439097), Clare Zarka (14432211), Jaslyn Johnson (14432223)   +13 more
core   +1 more source

LncRNA H19 promotes the proliferation of pulmonary artery smooth muscle cells through AT1R via sponging let-7b in monocrotaline-induced pulmonary arterial hypertension

Respiratory Research, 2018
Background Pulmonary arterial hypertension (PAH) is related to inflammation, and the lncRNA H19 is associated with inflammation. However, whether PDGF-BB-H19-let-7b-AT1R axis contributes to the pathogenesis of PAH has not been thoroughly elucidated to ...
Hua Su, Xiaoling Xu, Chao Yan, Yangfeng Shi, Yanjie Hu, Liangliang Dong, Songmin Ying, Kejing Ying, Ruifeng Zhang   +8 more
doaj   +1 more source

Remote Ischemic Preconditioning Contributes to the Expression of Long Non-Coding RNA H19 and Hypoxia-Inducible Factor-1α during Isolated Coronary Artery Bypass Graft Surgery in Patients with Ischemic Heart Disease

Український журнал серцево-судинної хірургії, 2020
The aim. The aim of our study was to establish the expression levels of long non-coding RNA H19 and hypoxiainducible factor-1α (HIF-1α) in the myocardium and leukocyte fraction as a possible mechanism of adaptation to remote ischemic preconditioning ...
M. Khetsuriani, N. Ioffe, M. Rudenko, T. Drevytska, V. Dosenko   +4 more
doaj   +1 more source

Long Non-coding RNA H19 Regulates Porcine Satellite Cell Differentiation Through miR-140-5p/SOX4 and DBN1

Frontiers in Cell and Developmental Biology, 2020
The H19 gene promotes skeletal muscle differentiation in mice, but the regulatory models and mechanisms of myogenesis regulated by H19 are largely unknown in pigs.
Jingxuan Li, Jingxuan Li, Jingxuan Li, Tao Su, Tao Su, Cheng Zou, Cheng Zou, Wenzhe Luo, Wenzhe Luo, Gaoli Shi, Gaoli Shi, Lin Chen, Lin Chen, Chengchi Fang, Chengchi Fang, Chengchi Fang, Changchun Li, Changchun Li, Changchun Li   +18 more
doaj   +1 more source