Results 21 to 30 of about 41,559 (188)

Role of LncRNA H19 in promoting endometrial deciduation

陆军军医大学学报, 2023
Objective To explore the effect of LncRNA H19 on endometrial decidualization. Methods The expression of LncRNA H19 in decidual tissues of spontaneous abortion and induced abortion was detected by RT-qPCR; The expression of LncRNA H19 in non-pregnant ...
WANG Tingting, HUANG Jinglin, MAO Yanhua, ZHANG Yingfeng, SUN Congcong   +4 more
doaj   +1 more source

Long non coding RNA H19: An emerging therapeutic target in fibrosing diseases

Autoimmunity, 2020
Fibrosis is characterised by excessive deposition of the extracellular matrix (ECM) and develops because of fibroblast differentiation during the process of inflammation. There are few effective treatment options for this diseases due to the aetiology of
Juan Li, Long-Ting Cao, Hong-Hui Liu, Xiao-Dong Yin, Jing Wang   +4 more
doaj   +1 more source

A G-quadruplex structure at the 5′ end of the H19 coding region regulates H19 transcription [PDF]

, 2017
The H19 gene, one of the best known imprinted genes, encodes a long non-coding RNA that regulates cell proliferation and differentiation. H19 RNA is widely expressed in embryonic tissues, but its expression is restricted in only a few tissues after birth.
Ma, Yue, Fumiko Toyoshima, Yue Ma, Mitsuko Fukuhara, Fukuhara, Mitsuko, Kazuo Nagasawa, Nagasawa, Kazuo, Toyoshima, Fumiko   +7 more
core   +1 more source

Data from: Orientation of mouse H19 ICR affects imprinted H19 gene expression through promoter methylation–dependent and –independent mechanisms

, 2021
The mouse Igf2/H19 locus is regulated by genomic imprinting, in which the paternally methylated H19 imprinting control region (ICR) plays a critical role in mono-allelic expression of the genes in the locus.
Miyajima, Yu, Matsuzaki, Hitomi, Fukamizu, Akiyoshi, Tanimoto, Keiji   +3 more
core   +1 more source

LncRNA-H19 Drives Cardiomyocyte Senescence by Targeting miR-19a/socs1/p53 Axis

Frontiers in Pharmacology, 2021
Purpose: Cardiomyocyte senescence is associated with a progressive decline in cardiac physiological function and the risk of cardiovascular events. lncRNA H19 (H19), a well-known long noncoding RNA (lncRNA), is involved in the pathophysiological process ...
Yuting Zhuang, Tingting Li, Hongwen Xiao, Jiaxu Wu, Shuang Su, Xue Dong, Xiaoxi Hu, Qi Hua, Junwu Liu, Wendi Shang, Jiaming Ju, Fei Sun, Zhenwei Pan, Yanjie Lu, Yanjie Lu, Mingyu Zhang   +15 more
doaj   +1 more source

Genomic imprinting defects in the growth disorder Beckwith-Wiedemann syndrome [PDF]

, 2009
The imprinting control region (IC1) of the human IGF2 and H19 genes is represented by a chromatin insulator located between the two genes that prevents the activation of IGF2 and allows the activation of H19 on the maternal chromosome. Deletions removing
Citro, Valentina
core   +1 more source

PreImplantation Factor Promotes Neuroprotection by Modulating Long Non-Coding RNA H19 of the Neuronal Stem Cells. [PDF]

, 2018
Purpose: Successful therapies for periventricular leukomalacia (PVL) in premature infants are lacking. Post-injury activation of neural stem cells (NSCs) represents an attractive strategy and long non-coding RNA H19 is a candidate to regulate cell ...
Barnea, Eytan, S Ornaghi, Ornaghi, S, Bordey, A, Surbek, D, Paidas, M, D Surbek, Mueller, M, Paidas, Michael, Spinelli, M, Ornaghi, Sara, Schoeberlein, A, M Spinelli, M Mueller, Barnea, E, Müller, Martin, A Schoeberlein, E Barnea, A Bordey, Spinelli, Marialuigia, Bordey, Angelique, Schoeberlein, Andreina, M Paidas, Surbek, Daniel   +23 more
core   +3 more sources

Altered Expression of Long Non-Coding RNAs NEAT1, H19, and MALAT1 in Peripheral Blood ‎Cells of Patients with Allergic Rhinitis after Treatment with Pharmaceutical Combinations of ‎ Budesonide and Fexofenadine versus Fluticasone Propionate and Fexofenadine

مجله علمی دانشگاه علوم پزشکی کردستان, 2023
Background and Aim: Allergic rhinitis is the most common chronic inflammatory disorder of the nasal mucosa. Long non-coding RNAs (lncRNA) are a group of non-coding RNAs involved in the pathogenesis of various inflammatory diseases. This study intended to
Gelayol Asadi, Sara Falahi, Misagh Rajabinejad, Parisa Feizollahi, Seyyed Hamidreza Mortazavi, Ali Gorgin Karaji, Farhad Salari, Alireza Rezaiemanesh   +7 more
doaj  

Delta-like and gtl2 are reciprocally expressed, differentially methylated linked imprinted genes on mouse chromosome 12 [PDF]

, 2000
The distal portion of mouse chromosome 12 is imprinted. To date, however, Gtl2 is the only imprinted gene identified on chromosome 12. Gtl2 encodes multiple alternatively spliced transcripts with no apparent open reading frame.
Tevendale, M, Johnson, M.H., Takada, S, M.H. Johnson, Ferguson-Smith, A.C., Paulsen, M, T. Freeman, Georgiades, P., Paulsen, M., Baker, J., Freeman, T, Campbell, E., Campbell, E, Tevendale, M., A.C. Ferguson-Smith, Georgiades, P, Freeman, T., P. Georgiades, S. Takada, M. Tevendale, M. Paulsen, E. Campbell, Johnson, M H, Baker, J, Ferguson-Smith, A C, J. Baker, Takada, S.   +26 more
core   +1 more source

The H19/let-7 double-negative feedback loop contributes to glucose metabolism in muscle cells [PDF]

, 2014
The H19 lncRNA has been implicated in development and growth control and is associated with human genetic disorders and cancer. Acting as a molecular sponge, H19 inhibits microRNA (miRNA) let-7.
Roden, Michael, Carmichael, Gordon G, Huang, Yingqun, Jurczak, Michael,, Yan, Lei, Szendroedi, Julia, Mueller, Martin, Shulman, Gerald, I, Carmichael, Gordon, G, Shulman, Gerald I, Yang, Lihua, Flannery, Clare, Carmichael, Gordon,, Jurczak, Michael, J, Zhou, Xiao-Bo, Taylor, Hugh, Gao, Yuan, Wu, Fuju, Zhou, Jichun, Müller, Martin, Shulman, Gerald,, Jurczak, Michael J, Dandolo, Luisa, Lee, Hui-Young   +23 more
core   +3 more sources