The rapid evolution of influenza A viruses poses a great challenge to vaccine development. Analytical and machine learning models have been applied to facilitate the process of antigenicity determination.
Eva K. Lee +2 more
doaj +1 more source
Exposure to particulate matter (PM) has been associated with increased hospital admissions for influenza. Airway epithelial cells are a primary target for inhaled environmental insults including fine PM (PM2.5) and influenza viruses.
Yinbiao Wang +13 more
doaj +1 more source
Emerging viral respiratory tract infections—environmental risk factors and transmission [PDF]
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Al-Tawfiq, Jaffar A. +6 more
core +1 more source
Cross-protection against European swine influenza viruses in the context of infection immunity against the 2009 pandemic H1N1 virus : studies in the pig model of influenza [PDF]
Pigs are natural hosts for the same influenza virus subtypes as humans and are a valuable model for cross-protection studies with influenza. In this study, we have used the pig model to examine the extent of virological protection between a) the 2009 ...
A Krumbholz +58 more
core +6 more sources
Neutralizing DNA Aptamers against Swine Influenza H3N2 Viruses [PDF]
ABSTRACT Triple reassortant influenza A viruses (IAVs) of swine, particularly the North American H3N2 subtype, circulate in swine herds and may reassort and result in the emergence of novel zoonotic strains. Current diagnostic tools rely on isolation of the viruses, followed by serotyping by hemagglutination or genome sequencing,
Manoosak, Wongphatcharachai +6 more
openaire +2 more sources
Rapport national de mi-saison sur l’influenza au Canada, 2019 à 2020
Au Canada, la saison nationale de la grippe a commencé à la semaine 47, entre le 17 et le 23 novembre 2019. Des 3 762 détections des cas de grippe confirmées en laboratoire ayant été signalées entre le 25 août et le 14 décembre 2019, 61 % étaient de type
Claire Sevenhuysen +7 more
doaj +1 more source
Long-lasting cross-protection against influenza A by neuraminidase and M2e-based immunization strategies [PDF]
There is mounting evidence that in the absence of neutralizing antibodies cross-reactive T cells provide protection against pandemic influenza viruses. Here, we compared protection and CD8+ T cell responses following challenge with H1N1 2009 pandemic and
Callewaert, Nico +9 more
core +2 more sources
H3N2 influenza viruses in humans: Viral mechanisms, evolution, and evaluation
Annual seasonal influenza vaccines are composed of two influenza A strains representing the H1N1 and H3N2 subtypes, and two influenza B strains representing the Victoria and Yamagata lineages.
James D. Allen, Ted M. Ross
doaj +1 more source
Whole-genome sequences of two influenza A (H3N2) virus strains isolated from Qinghai, China
Influenza A (H3N2) virus has a faster evolution rate than other types of influenza viruses. In this study, whole genome sequencing was performed to better understand the molecular evolution of influenza H3N2 and the protective effect of influenza virus ...
Juan Yu, Shengcang Zhao, Huaxiang Rao
doaj +1 more source
Influenza Evolution and H3N2 Vaccine Effectiveness, with Application to the 2014/2015 Season [PDF]
Influenza A is a serious disease that causes significant morbidity and mortality, and vaccines against the seasonal influenza disease are of variable effectiveness.
Deem, Michael W., Li, Xi
core +2 more sources

