Results 61 to 70 of about 50,945 (202)

Overview of Serological Techniques for Influenza Vaccine Evaluation: Past, Present and Future [PDF]

, 2014
Serological techniques commonly used to quantify influenza-specific antibodies include the Haemagglutination Inhibition (HI), Single Radial Haemolysis (SRH) and Virus Neutralization (VN) assays.
Callow, Calza, Chan, Cosma, De Jong, Farrohi, Ferrara, Fox, Frank, Fulton, Gross, Halloran, Harmon, Hierholzer, Johansson, Johansson, Kendal, Kilbourne, Montomoli, Okuno, O’Neill, Powers, Probert, Rowe, Schild, Schulman, Schulman, Scott, Sylte, Van Assen, Yewdell   +30 more
core   +3 more sources

Attenuation of Influenza a Virus into Live Vaccines Through C‐End Degrons

Advanced Science, EarlyView.
Naturally occurring C‐end degrons are exploited to design proteolysis‐targeting live attenuated influenza vaccines. C‐end degron tagging of viral M1 protein promotes proteasome‐dependent degradation, resulting in robust attenuation in host cells while permitting scalable production in engineered cells.
Ping Wang, Le Li, Yunfang Chen, Le Tong, Zhen Li, Rong Yu, Quan Shen, Qikai Wang, Jihuan Hou, Qisi Zhang, Xu Si, Ning Wang, Demin Zhou, Wen‐xia Tian, Longlong Si   +14 more
wiley   +1 more source

Ineffectiveness of the 2014-2015 H3N2 influenza vaccine

Oncotarget, 2015
The seasonal influenza vaccine is currently the most effective preventive modality against influenza infection. Nasopharyngeal samples of vaccinated and non-vaccinated patients presenting with Influenza-like-illness (ILI) were collected from over 20 outpatient clinics located in different geographic parts of Israel and were tested for the presence of ...
Michal, Mandelboim, Aharona, Glatman-Freedman, Yaron, Drori, Hilda, Sherbany, Rakefet, Pando, Hanna, Sefty, Hila, Zadka, Tamar, Shohat, Nathan, Keller, Ella, Mendelson   +9 more
openaire   +3 more sources

Comparative Analysis of Whole-Transcriptome RNA Expression in MDCK Cells Infected With the H3N2 and H5N1 Canine Influenza Viruses

Frontiers in Cellular and Infection Microbiology, 2019
This study aimed to detect changes in the complete transcriptome of MDCK cells after infection with the H5N1 and H3N2 canine influenza viruses using high-throughput sequencing, search for differentially expressed RNAs in the transcriptome of MDCK cells ...
Pan Tao, Pan Tao, Pan Tao, Zhangyong Ning, Xiangqi Hao, Xiangqi Hao, Xiangqi Hao, Xi Lin, Xi Lin, Xi Lin, Qingxu Zheng, Qingxu Zheng, Qingxu Zheng, Shoujun Li, Shoujun Li, Shoujun Li   +15 more
doaj   +1 more source

A bivalent live-attenuated influenza vaccine for the control and prevention of H3N8 and H3N2 canine influenza viruses [PDF]

, 2017
Canine influenza viruses (CIVs) cause a contagious respiratory disease in dogs. CIV subtypes include H3N8, which originated from the transfer of H3N8 equine influenza virus (EIV) to dogs; and the H3N2, which is an avian-origin virus adapted to infect ...
Martínez-Sobrido, Luis, Murcia, Pablo R., Nogales, Aitor, Parrish, Colin, Rodriguez, Laura   +4 more
core   +1 more source

Explaining the geographical origins of seasonal influenza A (H3N2) [PDF]

Proceedings of the Royal Society B: Biological Sciences, 2016
Most antigenically novel and evolutionarily successful strains of seasonal influenza A (H3N2) originate in East, South and Southeast Asia. To understand this pattern, we simulated the ecological and evolutionary dynamics of influenza in a host metapopulation representing the temperate north, tropics and temperate south.
Frank Wen, Trevor Bedford, Sarah Cobey
openaire   +3 more sources

Phosphoproteomics to Characterize Host Response During H3N2 Canine Influenza Virus Infection of Dog Lung

Frontiers in Veterinary Science, 2020
Avian-origin H3N2 canine influenza viruses (CIVs) cause severe contagious respiratory disease in dogs, and quickly adapt to new environments. To further understand the mechanism of virus infection and host-virus interactions, we characterized the ...
Yongbo Liu, Yongbo Liu, Yongbo Liu, Cheng Fu, Shaotang Ye, Shaotang Ye, Shaotang Ye, Yingxin Liang, Yingxin Liang, Yingxin Liang, Zhonghe Qi, Zhonghe Qi, Zhonghe Qi, Congwen Yao, Congwen Yao, Congwen Yao, Zhen Wang, Zhen Wang, Zhen Wang, Ji Wang, Ji Wang, Ji Wang, Siqi Cai, Siqi Cai, Siqi Cai, Shiyu Tang, Shiyu Tang, Shiyu Tang, Ying Chen, Ying Chen, Ying Chen, Shoujun Li, Shoujun Li, Shoujun Li   +33 more
doaj   +1 more source

Simultaneous co-infection with swine influenza A and porcine reproductive and respiratory syndrome viruses potentiates adaptive immune responses

Frontiers in Immunology, 2023
Porcine respiratory disease is multifactorial and most commonly involves pathogen co-infections. Major contributors include swine influenza A (swIAV) and porcine reproductive and respiratory syndrome (PRRSV) viruses.
Tiphany Chrun, Emmanuel A. Maze, Kelly J. Roper, Eleni Vatzia, Basudev Paudyal, Adam McNee, Veronica Martini, Tanuja Manjegowda, Graham Freimanis, Adrian Silesian, Noemi Polo, Becky Clark, Emily Besell, Georges Booth, Brigid Veronica Carr, Matthew Edmans, Alejandro Nunez, Surapong Koonpaew, Nanchaya Wanasen, Simon P. Graham, Elma Tchilian   +20 more
doaj   +1 more source

Genesis and pathogenesis of the 1918 pandemic H1N1 influenza A virus [PDF]

, 2014
The source, timing, and geographical origin of the 1918–1920 pandemic influenza A virus have remained tenaciously obscure for nearly a century, as have the reasons for its unusual severity among young adults.
A. Rambaut, Adalja, Antonovics, Davenport, Dowdle, Fan, FROST, G.-Z. Han, Kawaoka, KENDAL, M. Worobey, Masurel, Masurel, Masurel, Masurel, Molinari, Morens, Mulder, Nelson, REKART, SCHOENBAUM, Schulman, Shanks, Shanks, Taubenberger, Thompson, Thompson, Waffarn, Webster, Wolfe   +29 more
core   +2 more sources

Antigen specificity, not tissue compartment, determines clonal sharing among respiratory tract CD8+ resident memory T cells

Immunology &Cell Biology, EarlyView.
Abstract Tissue‐resident memory (Trm) CD8+ T cells in the upper and lower respiratory tract play an instrumental role in combatting influenza virus. While CD8+ Trm populations in these compartments differ in longevity and developmental requirements, it remains unclear whether they share clonotypes, indicating a common origin, or are seeded by distinct ...
Thi H O Nguyen, Hayley A McQuilten, Angela Pizzolla, Sneha Sant, Kim L Harland, Jessica Braverman, Katherine Kedzierska, Linda M Wakim   +7 more
wiley   +1 more source