Subunit vaccine H56/CAF01 induces a population of circulating CD4 T cells that traffic into the Mycobacterium tuberculosis-infected lung [PDF]
Mucosal Immunology, 2017 The capacity of CD4 T cells to protect against Mycobacterium tuberculosis (Mtb) is governed by their ability to localize to the lung site of infection. Subunit vaccine H56/CAF01, a liposome-adjuvanted fusion protein of Mtb antigens Ag85B, ESAT-6, and Rv2660, conferred durable protection and elicited polyfunctional CD4 T cells that preferentially ...
Woodworth, J.S. +6 more
openaire +2 more sources
Drivers of Greek and Turkish Defense Spending
International Journal of Management and Economics, 2016 This paper evaluates the factors responsible for maintaining substantial military expenditures in Greece and Turkey. The presented research encompasses theoretical and empirical aspects.
Waszkiewicz Grzegorz
doaj +1 more source
Business for peace: How entrepreneuring contributes to Sustainable Development Goal 16
Business Research Quarterly, 2023 We examine entrepreneurial ventures in a post-conflict context to identify practices that are helpful for companies operating in conflict zones while contributing to the United Nations’ Sustainable Development Goal 16 (SDG 16)—Peace, Justice, and Strong ...
Peter Jack Gallo +2 more
doaj +1 more source
Gold-Catalyzed Intramolecular Aminoarylation of Alkenes: C-C Bond Formation through Bimolecular Reductive Elimination [PDF]
, 2010 Gold-ilocks and the 3 mol % catalyst: Bimetallic gold bromides allow the room temperature aminoarylation of unactivated terminal olefins with aryl boronic acids using Selectfluor as an oxidant.
Benitez, Diego +6 more
core +1 more source
Mechanism of the Aerobic Oxidation of Alcohols by Palladium Complexes of N-Heterocyclic Carbenes [PDF]
, 2006 Quantum mechanics (B3LYP density functional theory) combined with solvation (Poisson−Boltzmann polarizable continuum solvent model) was used to investigate six mechanisms for the aerobic oxidation of alcohols catalyzed by (NHC)Pd(carboxylate)_2(H_2O ...
Goddard, William A., III +1 more
core +1 more source
EBioMedicine, 2018 Despite inducing strong T cell responses, Mycobacterium tuberculosis (Mtb) infection fails to elicit protective immune memory. As such latently infected or successfully treated Tuberculosis (TB) patients are not protected against recurrent disease. Here,
Thomas Lindenstrøm +5 more
doaj +1 more source
Mucosal delivery of tuberculosis vaccines: a review of current approaches and challenges. [PDF]
, 2019 Introduction: Tuberculosis (TB) remains a major health threat and it is now clear that the current vaccine, BCG, is unable to arrest the global TB epidemic. A new vaccine is needed to either replace or boost BCG so that a better level of protection could
Barclay WR +8 more
core +1 more source
A Computational Model Relating Structure and Reactivity in Enantioselective Oxidations of Secondary Alcohols by (−)-Sparteine−Pd^(II) Complexes [PDF]
, 2004 The key interactions responsible for the unique reactivity of (−)-sparteine−PdX_2 complexes (X = chloride, acetate) in the enantioselective oxidation of secondary alcohols have been elucidated using quantum mechanics (B3LYP DFT with the PBF polarizable ...
Goddard, William A., III +3 more
core +1 more source
Crop Science, Volume 66, Issue 1, January/February 2026.Abstract Six sets of 48 maize (Zea mays L.) inbred lines, and their 96 single crosses generated using the North Carolina Mating Design II system, were evaluated for resistance to gray leaf spot (GLS). The aim of the study was to assess the implications of combining ability, heterotic effects, and potence ratio in breeding for GLS resistance in maize ...
James O. Nyanapah +4 more
wiley +1 more source
The multistage vaccine H56 boosts the effects of BCG to protect cynomolgus macaques against active tuberculosis and reactivation of latent Mycobacterium tuberculosis infection [PDF]
Journal of Clinical Investigation, 2012 It is estimated that one-third of the world's population is infected with Mycobacterium tuberculosis. Infection typically remains latent, but it can reactivate to cause clinical disease. The only vaccine, Mycobacterium bovis bacillus Calmette-Guérin (BCG), is largely ineffective, and ways to enhance its efficacy are being developed.
Philana Ling, Lin +16 more
openaire +2 more sources