Results 41 to 50 of about 4,028 (164)

Optimisation of a murine splenocyte mycobacterial growth inhibition assay using virulent Mycobacterium tuberculosis

open access: yesScientific Reports, 2017
In the absence of a validated correlate of protection or robust animal models for human tuberculosis, Mycobacterial growth inhibition assays (MGIAs) aim to assess vaccines ability to inhibit mycobacterial growth in-vitro.
Christina Jensen   +4 more
doaj   +1 more source

Combining ability and heterosis in partial resistance to gray leaf spot in elite maize (Zea mays L.) genotypes

open access: yesCrop Science, Volume 66, Issue 1, January/February 2026.
Abstract Six sets of 48 maize (Zea mays L.) inbred lines, and their 96 single crosses generated using the North Carolina Mating Design II system, were evaluated for resistance to gray leaf spot (GLS). The aim of the study was to assess the implications of combining ability, heterotic effects, and potence ratio in breeding for GLS resistance in maize ...
James O. Nyanapah   +4 more
wiley   +1 more source

EFFECT OF H56/28 (APTINE) ON CATECHOLAMINE‐INDUCED ARRHYTHMIAS AND NEUROMUSCULAR TRANSMISSION IN MAN

open access: yesActa Anaesthesiologica Scandinavica, 1969
SUMMARYThe beta adrenergic blocking agent H56/28 was found to be effective in the prevention of catecholamine‐anesthetic cardiac arrhythmias in man. It was suggested that this antiarrhythmic action was due to beta adrenergic blockade rather than the local anesthetic activity which H56/28 is known to possess.
openaire   +3 more sources

Clinical Validation of Digital PCR for Precise m.3243A>G Heteroplasmy Quantification in Early‐Onset Diabetes

open access: yesJournal of Diabetes Research, Volume 2026, Issue 1, 2026.
Background Mitochondrial DNA m.3243A>G variant causes maternally inherited diabetes with deafness. We developed a droplet digital PCR (dPCR) assay to quantify m.3243A>G heteroplasmy and investigated its prevalence in Chinese Han early‐onset diabetes patients.
Xiaomu Kong   +14 more
wiley   +1 more source

Analysis of gene expression profiles in two spinal cord injury models

open access: yesEuropean Journal of Medical Research, 2022
Objectives To analyze the changes of gene expression at different timepoints after spinal cord injury (SCI) with tenth segment thoracic injury. Methods Two SCI models, the complete paraplegia (H) and Allen’s strike (D) methods were applied to induce SCI ...
Haifeng Yuan   +5 more
doaj   +1 more source

Pleistocene Climate Changes and Lineage Diversification of Sphenarium Grasshoppers (Orthoptera: Pyrgomorphidae)

open access: yesEcology and Evolution, Volume 15, Issue 10, October 2025.
We investigate the phylogeographic history and paleodistribution patterns of four closely related grasshopper species of the genus Sphenarium to test the relative impact of Pleistocene climate fluctuations on their diversification. We found that each species responded differently to these fluctuations, but their divergence, distribution, and ...
Salomón Sanabria‐Urbán   +4 more
wiley   +1 more source

National Security Issues in War Conditions – The Case of Ukraine: Economic and Environmental Dimensions

open access: yesReview of Economic Perspectives
The relevance of this research topic sustertems from the emergence of a whole range of systemic risks and threats resulting from the war in Ukraine. Russia’s full-scale aggression has exacerbated existing crises and given rise to new challenges in the ...
Iermakova Olga   +2 more
doaj   +1 more source

Positive selection within the Schizophrenia-associated GABA(A) receptor beta(2) gene. [PDF]

open access: yesPLoS ONE, 2007
The gamma-aminobutyric acid type-A (GABA(A)) receptor plays a major role in inhibitory neurotransmissions. Intronic SNPs and haplotypes in GABRB2, the gene for GABA(A) receptor beta(2) subunit, are associated with schizophrenia and correlated with the ...
Wing-Sze Lo   +13 more
doaj   +1 more source

Unstained Blood Smear Analysis: A Review of Rule‐Based, Machine Learning, and Deep Learning Techniques

open access: yesJournal of Biophotonics, Volume 18, Issue 10, October 2025.
Bright‐field images of unstained smears. (1) Sparse erythrocytes allow straightforward intensity‐ or phase‐based segmentation. (2) Overlapping cells blur boundaries, causing over‐ or under‐segmentation and lowering rule‐based accuracy, thus motivating overlap‐aware algorithms for reliable downstream feature extraction and classification. ABSTRACT Blood
Husnu Baris Baydargil, Thomas Bocklitz
wiley   +1 more source

A small RNA encoded in the Rv2660c locus of Mycobacterium tuberculosis is induced during starvation and infection.

open access: yesPLoS ONE, 2013
Enhanced transcription of the Rv2660c locus in response to starvation of Mycobacterium tuberculosis H37Rv encouraged addition of the predicted Rv2660c protein to an improved vaccine formulation.
Joanna Houghton   +8 more
doaj   +1 more source

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