Results 51 to 60 of about 10,208 (189)
Background Mitochondrial DNA m.3243A>G variant causes maternally inherited diabetes with deafness. We developed a droplet digital PCR (dPCR) assay to quantify m.3243A>G heteroplasmy and investigated its prevalence in Chinese Han early‐onset diabetes patients.
Xiaomu Kong +14 more
wiley +1 more source
Th1 immune responses can be modulated by varying dimethyldioctadecylammonium and distearoyl-sn-glycero-3-phosphocholine content in liposomal adjuvants [PDF]
OBJECTIVES: Cationic liposomes of dimethyldioctadecylammonium bromide (DDA) combined with trehalose 6,6'-dibehenate (TDB) elicit strong cell-mediated and antibody immune responses; DDA facilitates antigen adsorption and presentation while TDB potentiates
Bramwell, Vincent W. +4 more
core +1 more source
We investigate the phylogeographic history and paleodistribution patterns of four closely related grasshopper species of the genus Sphenarium to test the relative impact of Pleistocene climate fluctuations on their diversification. We found that each species responded differently to these fluctuations, but their divergence, distribution, and ...
Salomón Sanabria‐Urbán +4 more
wiley +1 more source
In the absence of a validated correlate of protection or robust animal models for human tuberculosis, Mycobacterial growth inhibition assays (MGIAs) aim to assess vaccines ability to inhibit mycobacterial growth in-vitro.
Christina Jensen +4 more
doaj +1 more source
ESAT-6 (EsxA) and TB10.4 (EsxH) based vaccines for pre- and post-exposure tuberculosis vaccination. [PDF]
The ESX systems from Mycobacterium tuberculosis are responsible for the secretion of highly immunogenic proteins of key importance for bacterial survival and growth. The two prototypic proteins, ESAT-6 (EsxA from ESX-1) and TB10.4 (EsxH from ESX-3) share
Truc Hoang +8 more
doaj +1 more source
Bright‐field images of unstained smears. (1) Sparse erythrocytes allow straightforward intensity‐ or phase‐based segmentation. (2) Overlapping cells blur boundaries, causing over‐ or under‐segmentation and lowering rule‐based accuracy, thus motivating overlap‐aware algorithms for reliable downstream feature extraction and classification. ABSTRACT Blood
Husnu Baris Baydargil, Thomas Bocklitz
wiley +1 more source
Abstract Thanasimus formicarius (L.) (Coleoptera: Cleridae) is an important bark beetle predator and can reduce bark beetle population densities of some of the most severe forest pests in Europe. We analysed the population genetics and phylogeography of T.
Eva Papek +19 more
wiley +1 more source
Analysis of gene expression profiles in two spinal cord injury models
Objectives To analyze the changes of gene expression at different timepoints after spinal cord injury (SCI) with tenth segment thoracic injury. Methods Two SCI models, the complete paraplegia (H) and Allen’s strike (D) methods were applied to induce SCI ...
Haifeng Yuan +5 more
doaj +1 more source
SECURITY PRIORITIES IN ASSESSING THE EFFECTIVENESS OF DOMESTIC ENTERPRISES
. The article establishes a causal relationship between economic security and efficiency of the enterprise and hypothesizes about the need to expand approaches to analytical evaluation of efficiency, taking into account the security priorities of the ...
L. Hnylytska +4 more
doaj +1 more source
A Computational Model Relating Structure and Reactivity in Enantioselective Oxidations of Secondary Alcohols by (−)-Sparteine−Pd^(II) Complexes [PDF]
The key interactions responsible for the unique reactivity of (−)-sparteine−PdX_2 complexes (X = chloride, acetate) in the enantioselective oxidation of secondary alcohols have been elucidated using quantum mechanics (B3LYP DFT with the PBF polarizable ...
Goddard, William A., III +3 more
core +1 more source

