Results 51 to 60 of about 3,884 (159)

A small RNA encoded in the Rv2660c locus of Mycobacterium tuberculosis is induced during starvation and infection.

open access: yesPLoS ONE, 2013
Enhanced transcription of the Rv2660c locus in response to starvation of Mycobacterium tuberculosis H37Rv encouraged addition of the predicted Rv2660c protein to an improved vaccine formulation.
Joanna Houghton   +8 more
doaj   +1 more source

Assisted return programmes across Europe – Mapping an increasingly obscure landscape

open access: yesInternational Migration, Volume 63, Issue 3, June 2025.
Abstract Amidst an increasing popularity of Assisted Return (AR) programmes amongst European states, on the one hand, and criticism pertaining to their voluntary and humanitarian nature, on the other hand, this paper maps AR programmes across Europe.
Lukas M. Fuchs
wiley   +1 more source

El gasto fiscal de la guerra contra los portadores de drogas ilícitas: una aproximación para Colombia

open access: yesLecturas de Economía, 2019
Alrededor del mundo, los gobiernos dedican un gran volumen de recursos públicos al control del porte, fabricación y tráfico de drogas ilícitas. En general, estos costos son difíciles de observar, pues corresponden al costo de oportunidad de muchos ...
Isabel Gutiérrez, Santiago Tobón
doaj   +1 more source

Lanthanides Gd and Tm Can Inhibit Carnitine/Acylcarnitine Transporter: Insights from All‐Atoms Simulations

open access: yesChemBioChem, Volume 26, Issue 8, April 14, 2025.
The inhibition of CAC transporter, an important mitochondrial protein, by Pr3+, Gd3+ and Tm3+ lanthanides is studied in the framework of all‐atoms MD simulations. In presence of cations, it is shown that c‐state to m‐state conformational change occurs spontaneously, providing atomistic explanation of the protein's channel occlusion and inhibition ...
Mario Prejanò   +4 more
wiley   +1 more source

The Socio-Economic Perspective for the Guns Vs. Butter Trade-Off in the European Union Countries

open access: yesFolia Oeconomica Stetinensia
At the NATO Wales Summit in 2014, European allies agreed to spend at least 2% of GDP on defence.1 However, the break-out of the Russo-Ukrainian war increased EU countries efforts to spend more on military capability not only because of solidarity in the ...
Waszkiewicz Grzegorz   +2 more
doaj   +1 more source

Where are we as the progress of therapeutic vaccination with regard to tuberculosis

open access: yesFrontiers in Microbiology, 2016
A major problem with tuberculosis (TB) control is the long duration of drug therapy –both for latent and for active TB. Therapeutic vaccination has been postulated to improve this situation, and to this end there are several candidates already in ...
Pere-Joan Cardona
doaj   +1 more source

Safety and efficacy of tuberculosis vaccine candidates in low- and middle-income countries: a systematic review of randomised controlled clinical trials

open access: yesBMC Infectious Diseases, 2023
Background Tuberculosis (TB) remains a leading cause of death worldwide, with 98% of cases occurring in low- and middle-income countries (LMICs). The only vaccine licenced for the prevention of TB has limited protection for adolescents, adults and ...
Lydia Wilson   +8 more
doaj   +1 more source

Pharmacological Dissection Identifies Retatrutide Overcomes the Therapeutic Barrier of Obese TNBC Treatments through Suppressing the Interplay between Glycosylation and Ubiquitylation of YAP

open access: yesAdvanced Science, Volume 12, Issue 11, March 20, 2025.
This study reveals that obesity‐driven metabolic dysfunction enhances YAP O‐GlcNAcylation, facilitating its stabilization by preventing ubiquitylation and degradation via EIF3H, thereby driving TNBC progression and chemoresistance. Retatrutide disrupts this axis by suppressing O‐GlcNAcylation, restoring YAP ubiquitylation, and enhancing degradation ...
Xin Cui   +9 more
wiley   +1 more source

The Concept of a Method for Predicting the Cascade Effect Under Conditions of Hybrid Warfare

open access: yesFoundations of Management
The changing nature of conflicts is creating new challenges in civilian protection. Features of hybrid warfare, such as multidimensionality, synergistic effects, blurring of boundaries, or asymmetricity, force practitioners and scholars to consider new ...
WRÓBLEWSKI Wojciech   +1 more
doaj   +1 more source

A global analysis of the role of uncertainty, globalisation, security and market concentration on domestic capital formation

open access: yesResearch in Globalization
This paper studies the dynamics between domestic physical capital formation and selected macroeconomic indicators (uncertainty, globalisation, security and market concentration) that have been given little consideration both within the theoretical scope ...
Gildas Dohba Dinga, Gisele Mah
doaj   +1 more source

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