Results 31 to 40 of about 10,208 (189)
Subunit vaccine H56/CAF01 induces a population of circulating CD4 T cells that traffic into the Mycobacterium tuberculosis-infected lung [PDF]
The capacity of CD4 T cells to protect against Mycobacterium tuberculosis (Mtb) is governed by their ability to localize to the lung site of infection. Subunit vaccine H56/CAF01, a liposome-adjuvanted fusion protein of Mtb antigens Ag85B, ESAT-6, and Rv2660, conferred durable protection and elicited polyfunctional CD4 T cells that preferentially ...
Woodworth, J.S. +6 more
openaire +2 more sources
The fractional parentage expansion method is extended from $SU(2)_{f}$ nonrelativistic to $SU(3)_{f}$ and relativistic dibaryon calculations. A transformation table between physical bases and symmetry bases for the $SU(3)_{f}$ dibaryon is provided.
B. Silvestre Brac +33 more
core +1 more source
On Influence seeks to explore the varied inspirations that have framed our own learning, research, and teaching experiences. At the core of the exhibit is the question: What led you to your field of study?
Aberle, Jessica
core +1 more source
Despite inducing strong T cell responses, Mycobacterium tuberculosis (Mtb) infection fails to elicit protective immune memory. As such latently infected or successfully treated Tuberculosis (TB) patients are not protected against recurrent disease. Here,
Thomas Lindenstrøm +5 more
doaj +1 more source
This graphical abstract illustrates the multi‐target antioxidant and anti‐inflammatory effects of AGF in alleviating liver injury, and their association with gut microbiota modulation and enrichment of beneficial microbes. ABSTRACT To investigate the antioxidant effects and underlying mechanisms of Ampelopsis grossedentata flavonoids (AGF) in rats fed ...
Hao Shi, Bo Zhou, Jing Wang, Li Lan Lei
wiley +1 more source
Formulation of inhalable delivery systems containing tuberculosis (TB) antigens to target the site of infection (lungs) have been considered for the development of subunit vaccines. Inert delivery systems such as poly (lactic-co-glycolic acid) (PLGA) are
Carla B. Roces +4 more
doaj +1 more source
Mucosal delivery of tuberculosis vaccines: a review of current approaches and challenges. [PDF]
Introduction: Tuberculosis (TB) remains a major health threat and it is now clear that the current vaccine, BCG, is unable to arrest the global TB epidemic. A new vaccine is needed to either replace or boost BCG so that a better level of protection could
Barclay WR +8 more
core +1 more source
Myeloid‐derived suppressor cells (MDSCs) are key contributors to cancer immunotherapy failure and major targets in new therapeutic strategies. We highlight therapeutic approaches to counteract their immunosuppressive functions and discuss recent efforts to optimize drug delivery for controlling MDSCs, focusing on resiquimod as a representative drug ...
Yanying He, Yoon Yeo
wiley +1 more source
ABSTRACT The SLOSS (Single Large or Several Small) debate is crucial in reserve design, focusing on evaluating the conservation efficacy of a single large reserve versus multiple small reserves for species preservation. While accumulating evidence suggests that multiple small reserves may conserve greater species diversity, the question of how to ...
Fumin Lei +7 more
wiley +1 more source
برآورد تابع تقاضای پویای مخارج دفاعی (مورد مطالعه: کشورهای سند چشمانداز 1404) [PDF]
حساسیت منطقه خاورمیانه و وجود مناقشات همیشگی در آن، سبب شده است سهم قابل توجهی از تولید ناخالص داخلی کشورهای این منطقه، به بخش دفاعی اختصاص داده شود. بر این اساس، هدف اصلی مقاله حاضر، برآورد تابع تقاضای مخارج دفاعی در 13 کشور خاورمیانه در سالهای 2014 ...
ابوالقاسم گل خندان
doaj +1 more source

