Results 11 to 20 of about 5,277,672 (304)

Regulation of hair cell and stomatal size by a hair cell-specific peroxidase in the grass Brachypodium distachyon. [PDF]

, 2023
The leaf epidermis is the outermost cell layer forming the interface between plants and the atmosphere that must both provide a robust barrier against (a)biotic stressors and facilitate carbon dioxide uptake and leaf transpiration.1 To achieve these ...
Berg, Lea S, Lindner, Heike, Michael T. Raissig, Tiago D.G. Nunes, Raissig, Michael T, Slawinska, Magdalena, Nunes, Tiago D G, Raissig, Michael, Jesenofsky, Barbara, Richard Sibout, Sibout, Richard, Vogel, John P, Leonie Redt, Vogel, John, Heike Lindner, John P. Vogel, Berg, Lea, Lea S. Berg, Nunes, Tiago D.G., Barbara Jesenofsky, Laudencia-Chingcuanco, Debbie, Redt, Leonie, Slawinska, Magdalena W, Zhang, Dan, Debbie Laudencia-Chingcuanco, Dan Zhang, Magdalena W. Slawinska   +26 more
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Initiation of Supporting Cell Activation for Hair Cell Regeneration in the Avian Auditory Epithelium: An Explant Culture Model

Frontiers in Cellular Neuroscience, 2020
Sensorineural hearing loss is a common disability often caused by the loss of sensory hair cells in the cochlea. Hair cell (HCs) regeneration has long been the main target for the development of novel therapeutics for sensorineural hearing loss.
Mami Matsunaga, Tomoko Kita, Ryosuke Yamamoto, Norio Yamamoto, Takayuki Okano, Koichi Omori, Satoko Sakamoto, Takayuki Nakagawa   +7 more
doaj   +1 more source

Ontogenetic development of inner ear hair cell organization in the New Zealand carpet shark Cephaloscyllium isabellum

Frontiers in Ecology and Evolution, 2022
IntroductionThe inner ear hair cells of fishes can provide insight into the early evolution of vertebrate inner ear structure. Fishes represent some of the first vertebrates to evolve auditory capacity, and the same basic structure, the sensory hair cell,
Derek J. Sauer, Kara E. Yopak, Craig A. Radford   +2 more
doaj   +1 more source

Beyond generalized hair cells: Molecular cues for hair cell types [PDF]

Hearing Research, 2013
Basic helix-loop-helix (bHLH) transcription factors (TFs) are crucial for inner ear neurosensory development. The proneural TF Atoh1 regulates the differentiation of hair cells (HCs) whereas Neurog1 and Neurod1 regulate specification and differentiation of neurons, respectively, but also affect HC development.
Israt, Jahan, Ning, Pan, Jennifer, Kersigo, Bernd, Fritzsch   +3 more
openaire   +2 more sources

Thyroxine differentially modulates the peripheral clock: lessons from the human hair follicle [PDF]

, 2015
The human hair follicle (HF) exhibits peripheral clock activity, with knock-down of clock genes (BMAL1 and PER1) prolonging active hair growth (anagen) and increasing pigmentation.
Haslam, Iain S., Iain S Haslam, Jonathan A Hardman, Hardman, Jonathan A, Bessam Farjo (714627), Farjo, Bessam, Nilofer Farjo (714626), Nilofer Farjo, Jonathan A. Hardman (714625), Ralf Paus, Farjo, Nilofer, Bessam Farjo, Iain S. Haslam (452871), Haslam, Iain S, Hardman, Jonathan A., Paus, Ralf, Ralf Paus (261703)   +16 more
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Regenerated hair cells in the neonatal cochlea are innervated and the majority co-express markers of both inner and outer hair cells

Frontiers in Cellular Neuroscience, 2022
After a damaging insult, hair cells can spontaneously regenerate from cochlear supporting cells within the first week of life. While the regenerated cells express several markers of immature hair cells and have stereocilia bundles, their capacity to ...
Mitchell L. Heuermann, Sophia Matos, Sophia Matos, Deborah Hamilton, Brandon C. Cox, Brandon C. Cox   +5 more
doaj   +1 more source

The Transcriptomics to Proteomics of Hair Cell Regeneration: Looking for a Hair Cell in a Haystack [PDF]

Microarrays, 2013
Mature mammals exhibit very limited capacity for regeneration of auditory hair cells, while all non-mammalian vertebrates examined can regenerate them. In an effort to find therapeutic targets for deafness and balance disorders, scientists have examined gene expression patterns in auditory tissues under different developmental and experimental ...
Smith, Michael E., Rajadinakaran, Gopinath   +1 more
openaire   +2 more sources

Insight into the early steps of root hair formation revealed by the procuste1 cellulose synthase mutant of Arabidopsis thaliana [PDF]

, 2008
Background: formation of plant root hairs originating from epidermal cells involves selection of a polar initiation site and production of an initial hair bulge which requires local cell wall loosening. In Arabidopsis the polar initiation site is located
Singh, Sunil K., Singh, Manoj, Marchant, Alan, Fischer, Urs, Grebe, Markus, Singh, Sunil, Grebe, Markus,, Alan Marchant, Singh, Sunil,, Urs Fischer, Manoj Singh, Sunil K Singh, Markus Grebe   +12 more
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Human hair follicles operate an internal Cori cycle and modulate their growth via glycogen phosphorylase

Scientific Reports, 2021
Hair follicles (HFs) are unique, multi-compartment, mini-organs that cycle through phases of active hair growth and pigmentation (anagen), apoptosis-driven regression (catagen) and relative quiescence (telogen).
Katarzyna Figlak, Greg Williams, Marta Bertolini, Ralf Paus, Michael P. Philpott   +4 more
doaj   +1 more source

Olfactory receptor OR2AT4 regulates human hair growth

Nature Communications, 2018
Increasing evidence suggest that olfactory receptors can carry additional functions besides olfaction. Here, Chéret et al. show that stimulation of the olfactory receptor ORT2A4 by the odorant Sandalore® stimulates growth of human scalp hair follicles ex
Jérémy Chéret, Marta Bertolini, Leslie Ponce, Janin Lehmann, Teresa Tsai, Majid Alam, Hanns Hatt, Ralf Paus   +7 more
doaj   +1 more source