AXR3 and SHY2 interact to regulate root hair development [PDF]
, 2003 Signal transduction of the plant hormone auxin centres on the regulation of the abundance of members of the Aux/IAA family of transcriptional regulators, of which there are 29 in Arabidopsis.
Grierson, C.S., Knox, K., Leyser, O.
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Differentiation of mammalian vestibular hair cells from conditionally immortal, postnatal supporting cells [PDF]
, 1999 We provide evidence from a newly established, conditionally immortal cell line (UB/UE-1) that vestibular supporting cells from the mammalian inner ear can differentiate postnatally into more than one variant of hair cell.
Holley, M.C. +4 more
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Selective deletion of cochlear hair cells causes rapid age-dependent changes in spiral ganglion and cochlear nucleus neurons [PDF]
, 2015 During nervous system development, critical periods are usually defined as early periods during which manipulations dramatically change neuronal structure or function, whereas the same manipulations in mature animals have little or no effect on the same ...
Hume, Clifford +8 more
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Cyclic dermal BMP signalling regulates stem cell activation during hair regeneration [PDF]
, 2008 In the age of stem cell engineering it is critical to understand how stem cell activity is regulated during regeneration. Hairs are mini-organs that undergo cyclic regeneration throughout adult life1, and are an important model for organ regeneration ...
A Durward +35 more
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The tip-link antigen, a protein associated with the transduction complex of sensory hair cells, is protocadherin-15 [PDF]
, 2006 Sound and acceleration are detected by hair bundles, mechanosensory structures located at the apical pole of hair cells in the inner ear. The different elements of the hair bundle, the stereocilia and a kinocilium, are interconnected by a variety of link
Ahmed, Zubair M +14 more
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Active hair bundle movements in auditory hair cells [PDF]
The Journal of Physiology, 2006 The frequency selectivity of mammalian hearing depends on not only the passive mechanics of the basilar membrane but also an active amplification of the mechanical stimulus by the cochlear hair cells. The common view is that amplification stems from the somatic motility of the outer hair cells (OHCs), changes in their length impelled by voltage ...
openaire +2 more sources
Retardation of cochlear maturation and impaired hair cell function caused by deletion of all known thyroid hormone receptors [PDF]
, 2001 The deafness caused by early onset hypothyroidism indicates that thyroid hormone is essential for the development of hearing. We investigated the underlying roles of the TRa1 and TRß thyroid hormone receptors in the auditory system using receptor ...
Forrest, Douglas +8 more
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Disrupting the Interaction between Retinoblastoma Protein and Raf-1 Leads to Defects in Progenitor Cell Proliferation and Survival during Early Inner Ear Development [PDF]
, 2013 The retinoblastoma protein (pRb) is required for cell-cycle exit of embryonic mammalian hair cells but is not required for hair cell fate determination and early differentiation, and this provides a strategy for hair cell regeneration by manipulating the
Chen, Yan +5 more
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Clinical Case ReportsThe combination of Renuvion helium plasma and Icoone Multi Micro Alveolar Stimulation is an effective, minimally invasive approach for reducing upper arm fat and improving skin texture.
Mohammad Ali Nilforoushzadeh +6 more
doaj +1 more source