Results 21 to 30 of about 11,068,075 (352)
Pattern formation in the basilar papilla: evidence for cell rearrangement. [PDF]
, 1997 The avian basilar papilla is composed of hair and supporting cells arranged in a regular pattern in which the hair cells are surrounded and isolated from each other by supporting cell processes.
Goodyear, Richard, Richardson, Guy
core +2 more sources
Stereociliary Myosin-1c Receptors Are Sensitive to Calcium Chelation and Absent from Cadherin 23 Mutant Mice [PDF]
, 2006 The identities of some of the constituents of the hair-cell transduction apparatus have been elucidated only recently. The molecular motor myosin-1c (Myo1c) functions in adaptation of the hair-cell response to sustained mechanical stimuli and is ...
Cyr, Janet L +4 more
core +1 more source
eLife, 2019 Loss of sensory hair cells leads to deafness and balance deficiencies. In contrast to mammalian hair cells, zebrafish ear and lateral line hair cells regenerate from poorly characterized support cells.
Mark E. Lush +13 more
semanticscholar +1 more source
Aminoglycoside-Induced Phosphatidylserine Externalization in Sensory Hair Cells Is Regionally Restricted, Rapid, and Reversible [PDF]
, 2008 The aminophospholipid phosphatidylserine (PS) is normally restricted to the inner leaflet of the plasma membrane. During certain cellular processes, including apoptosis, PS translocates to the outer leaflet and can be labeled with externally applied ...
Gale, Jonathan E +4 more
core +1 more source
Single-cell proteomics reveals changes in expression during hair-cell development
eLife, 2019 Hearing and balance rely on small sensory hair cells that reside in the inner ear. To explore dynamic changes in the abundant proteins present in differentiating hair cells, we used nanoliter-scale shotgun mass spectrometry of single cells, each ~1 ...
Ying Zhu +7 more
semanticscholar +1 more source
Transcriptomic Profiling of Zebrafish Hair Cells Using RiboTag
Frontiers in Cell and Developmental Biology, 2018 The zebrafish inner ear organs and lateral line neuromasts are comprised of a variety of cell types, including mechanosensitive hair cells. Zebrafish hair cells are evolutionarily homologous to mammalian hair cells, and have been particularly useful for ...
Maggie S. Matern +8 more
doaj +1 more source
Keratin-mediated hair growth and its underlying biological mechanism
Communications Biology, 2022 Injecting human hair-derived keratin into mice skin accelerates hair growth & formation, as TGFβ2 secretion during hair destruction stimulates epithelial cell death and keratin release, leading to dermal cell condensation & hair growth.
Seong Yeong An +10 more
doaj +1 more source
Frontiers in Cellular Neuroscience, 2021 Non-mammalian vertebrates can restore their auditory and vestibular hair cells naturally by triggering the regeneration of adjacent supporting cells. The transcription factor ATOH1 is a key regulator of hair cell development and regeneration in the inner
Amrita A. Iyer +4 more
doaj +1 more source
Hair Cell Transduction, Tuning, and Synaptic Transmission in the Mammalian Cochlea.
Comprehensive Physiology, 2017 Sound pressure fluctuations striking the ear are conveyed to the cochlea, where they vibrate the basilar membrane on which sit hair cells, the mechanoreceptors of the inner ear.
R. Fettiplace
semanticscholar +1 more source
Activated notch causes deafness by promoting a supporting cell phenotype in developing auditory hair cells. [PDF]
PLoS ONE, 2014 To determine whether activated Notch can promote a supporting cell fate during sensory cell differentiation in the inner ear.An activated form of the Notch1 receptor (NICD) was expressed in early differentiating hair cells using a Gfi1-Cre mouse allele ...
Grace Savoy-Burke +7 more
doaj +1 more source