Results 201 to 210 of about 5,738,873 (283)

An essential signaling cascade for avian auditory hair cell regeneration. [PDF]

open access: yesDev Cell
Benkafadar N   +6 more
europepmc   +1 more source

Somatic cell reprogramming for Parkinson's disease treatment

open access: yesIbrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

Aerogel Fiber: A One‐Dimensional Programmable Porous Matter for Next Thermal Management Materials

open access: yesInterdisciplinary Materials, EarlyView.
Aerogel fibers are redefined as one‐dimensional programmable porous matter, where thermal transport is governed by multiscale pathway engineering. By reconstructing and decoupling transport pathways from molecular to textile scales, these systems integrate insulation, radiative cooling, and adaptive thermal regulation.
Lizhi Ren   +6 more
wiley   +1 more source

Stem Cell-Based Hair Cell Regeneration and Therapy in the Inner Ear. [PDF]

open access: yesNeurosci Bull
Qi J   +9 more
europepmc   +1 more source

System‐Local Axes and Metabolic Reprogramming From Health to Response in House Dust Mite‐Specific Subcutaneous Immunotherapy for Allergic Rhinitis

open access: yesiMetaMed, EarlyView.
This study delineated nasal‐plasma metabolic reprogramming in house dust mite‐allergic rhinitis (HDM‐AR) and subcutaneous immunotherapy (SCIT) response, showing compartment‐specific signatures dominated by nasal lipid‐redox and plasma nucleotide‐NAD+ axes and across the HC–HDM‐AR–SCIT response continuum, dual‑compartment metabolites exhibited ...
Bixing Fang   +13 more
wiley   +1 more source

Mechanical memory in aging: From adaptive sensing to pathological entrenchment

open access: yesInterdisciplinary Medicine, EarlyView.
Mechanical memory in aging operates through four temporal tiers, from cytoskeletal remodeling to metabolic reprogramming. Aging disrupts this cascade through three distinct decoupling patterns: sensor degradation, conduction blockade, and execution failure, leading to irreversible pathological entrenchment across multiple organ systems.
Mingyang Huang   +7 more
wiley   +1 more source

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