Results 91 to 100 of about 50,414 (231)
Global Analysis of Protein Expression of Inner Ear Hair Cells
Journal of Neuroscience, 2017 The mammalian inner ear (IE) subserves auditory and vestibular sensations via highly specialized cells and proteins. Sensory receptor hair cells (HCs) are necessary for transducing mechanical inputs and stimulating sensory neurons by using a host of ...
Ann E. Hickox +7 more
semanticscholar +1 more source
Tsukushi is essential for the development of the inner ear
Molecular Brain, 2020 Tsukushi (TSK)—a small, secreted, leucine-rich-repeat proteoglycan—interacts with and regulates essential cellular signaling cascades. However, its functions in the mouse inner ear are unknown.
Toru Miwa +8 more
doaj +1 more source
The very large G-protein coupled receptor VLGR1: a component of the ankle link complex required for the normal development of auditory hair bundles [PDF]
, 2006 Sensory hair bundles in the inner ear are composed of stereocilia that can be interconnected by a variety of different link types, including tip links, horizontal top connectors, shaft connectors, and ankle links.
Birch, David G +10 more
core +1 more source
Postnatal maturation of auditory-nerve heterogeneity, as seen in spatial gradients of synapse morphology in the inner hair cell area [PDF]
Hearing Research, 2016 Auditory nerve fibers in the adult ear are divided into functional subgroups according to spontaneous rate (SR) and threshold sensitivity. The high-threshold, low-SR fibers are morphologically and spatially distinct from the low-threshold high-SR fibers at their synaptic contacts with inner hair cells.
M. Charles Liberman +2 more
openaire +3 more sources
Primary Culture and Plasmid Electroporation of the Murine Organ of Corti. [PDF]
, 2010 In all mammals, the sensory epithelium for audition is located along the spiraling organ of Corti that resides within the conch shaped cochlea of the inner ear (fig 1).
Brugeaud, Aurore +2 more
core +3 more sources
Journal of Neuroscience, 2016 The auxiliary subunit α2δ2 modulates the abundance and function of voltage-gated calcium channels. Here we show that α2δ2 mRNA is expressed in neonatal and mature hair cells.
B. Fell +9 more
semanticscholar +1 more source
A ratchet mechanism for amplification in low-frequency mammalian hearing
, 2010 The sensitivity and frequency selectivity of hearing result from tuned amplification by an active process in the mechanoreceptive hair cells. In most vertebrates the active process stems from the active motility of hair bundles.
A. J. Hudspeth +26 more
core +2 more sources
Aging, 2016 Genetic factors combined with oxidative stress are major determinants of age-related hearing loss (ARHL), one of the most prevalent disorders of the elderly.
D. Ding +8 more
semanticscholar +1 more source
Molecular Therapy: Methods & Clinical Development, 2016 Synaptopathy in the cochlea occurs when the connection between inner hair cells and the auditory nerve is disrupted, leading to impaired hearing and nerve degeneration. Experiments using transgenic mice have shown that overexpression of NT3 by supporting
Min Young Lee +7 more
doaj +1 more source
Live Demonstration: Real-time neuro-inspired sound source localization and tracking architecture applied to a robotic platform [PDF]
, 2018 This live demonstration presents a sound source localization and tracking system implemented with Spike Signal Processing (SSP) building blocks on FPGA devices.
Cerezuela Escudero, Elena +3 more
core