Results 111 to 120 of about 37,354 (236)

Studies of intercellular Ca2+ signaling and gap-junction coupling in the developing cochlea of mouse models affected by congenital hearing loss [PDF]

, 2013
Connexin 26 (Cx26) and connexin 30 (Cx30) form gap junction channels that allow the intercellular diffusion of the Ca2+ mobilizing second messenger IP3.
Rodriguez Hernandez, Laura
core   +1 more source

Developmental synaptic changes at the transient olivocochlear-inner hair cell synapse [PDF]

, 2019
In the mature mammalian cochlea, inner hair cells (IHCs) are mainly innervated by afferent fibers that convey sound information to the CNS. During postnatal development, however, medial olivocochlear (MOC) efferent fibers transiently innervate the IHCs ...
Elgoyhen, Ana Belen, Katz, Eleonora, Kearney, Graciela Inés, Vattino, Lucas Gabriel, Wedemeyer, Carolina, Zorrilla de San Martín, Javier   +5 more
core   +1 more source

The Current Situation and Development of Endoscopic Ear Surgery in China

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Endoscopic ear surgery has been widely performed in China since 2015 due to the development and rapid popularization of endoscopic technology. Due to the relative shortness of the auditory meatus, only a fixed endoscope is required in many cases, rather than a motion similar to a nasal endoscope, and uncontrollable bleeding is virtually non ...
Meng‐Wen Shi, Ge Yin, Yu Sun
wiley   +1 more source

Mechanosensitive Piezo channels and their potential roles in peripheral auditory perception

Brain-X
Hearing sound and responding to external and internal mechanical stimuli requires specific proteins as mechanotransducers that convert mechanical forces into biological signals.
Zhangyi Yi, Ge Yin, Chunjiang Wei, Yizhou Quan, Yu Sun   +4 more
doaj   +1 more source

Investigating the expression profiles of cysteine string proteins (CSPs) in cochlear tissue

Journal of Otology
Objective: This study aims to explore the expression patterns of cysteine string protein alpha (CSPα) and cysteine string protein beta (CSPβ) in the mammalian inner ear, with an emphasis on their temporal dynamics during the developmental stages of C57BL/
Shili Zhang, Caiji Wang, Yuehua Qiao, Xi Shi   +3 more
doaj   +1 more source

Stereociliary Myosin-1c Receptors Are Sensitive to Calcium Chelation and Absent from Cadherin 23 Mutant Mice [PDF]

, 2006
The identities of some of the constituents of the hair-cell transduction apparatus have been elucidated only recently. The molecular motor myosin-1c (Myo1c) functions in adaptation of the hair-cell response to sustained mechanical stimuli and is ...
Cyr, Janet L, Goodyear, Richard, Phillips, Kelli R, Richardson, Guy P, Tong, Song   +4 more
core   +1 more source

Electrocochleographic Changes Predict an Early Sign of Cochlear Degeneration

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives The purpose of this study is to identify the earliest appearing auditory electrophysiological indicators that change with age progression in young adults with normal hearing, and to analyze the frequency distribution patterns of these markers in the cochlear.
Min‐Fei Qian, Hao Chen, Qi‐Xuan Wang, Ya‐Qi Zhou, Xiao‐Lu Chen, Zhi‐Wu Huang, Ji‐Ping Li   +6 more
wiley   +1 more source

Improved Bone Conduction and Hearing Outcomes After Stapes Surgery for Otosclerosis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective To evaluate the improvement in bone conduction (BC) thresholds after stapes surgery for otosclerosis, compare the outcomes of surgical techniques, and analyze the short‐ and long‐term results to inform treatment strategies. Methods We retrospectively reviewed data from 173 patients (188 ears) who underwent total stapedectomy, partial
Na Zhang, Xiao‐Bo Ma, Dan‐Ni Wang, Yi Li, Yan Zheng, Yong‐Xin Li, Shou‐Qin Zhao   +6 more
wiley   +1 more source

Tmc1 point mutation affects Ca2+ sensitivity and block by dihydrostreptomycin of the mechanoelectrical transducer current of mouse outer hair cells [PDF]

, 2016
The transduction of sound into electrical signals depends on mechanically sensitive ion channels in the stereociliary bundle. The molecular composition of this mechanoelectrical transducer (MET) channel is not yet known.
Corns, Laura F, Johnson, Stuart L, Kros, Corne J, Marcotti, Walter   +3 more
core   +3 more sources

Severe Hearing Loss in the World's First Successfully Captive‐Born Yangtze Finless Porpoise: Impact of High Underwater Sound Exposure and Congenital Hearing Disorders

Integrative Zoology, EarlyView.
The audiogram of the world's first successfully captive‐born Yangtze finless porpoise was on average 40 dB higher than conspecifics. Congenital hearing disorders and noise exposure may be the primary cause of porpoise's hearing loss. ABSTRACT Aquariums globally have seen significant growth in recent decades.
Zhitao Wang, Tomonari Akamatsu, Kexiong Wang, Ding Wang   +3 more
wiley   +1 more source