Results 131 to 140 of about 50,414 (231)

Insights into the Biology of Hearing and Deafness Revealed by Single-Cell RNA Sequencing

Cell Reports, 2019
Summary: Single-cell RNA sequencing is a powerful tool by which to characterize the transcriptional profile of low-abundance cell types, but its application to the inner ear has been hampered by the bony labyrinth, tissue sparsity, and difficulty ...
Paul T. Ranum, Alexander T. Goodwin, Hidekane Yoshimura, Diana L. Kolbe, William D. Walls, Jin-Young Koh, David Z.Z. He, Richard J.H. Smith   +7 more
doaj  

Therapeutic potential of stem cells in auditory hair cell repair

Journal of Stem Cells and Regenerative Medicine, 2009
The prevalence of acquired hearing loss is very high. About 10% of the total population and more than one third of the population over 65 years suffer from debilitating hearing loss.
Ryuji Hata
doaj  

Auditory neuroscience: Development, transduction and integration [PDF]

, 2000
Hearing underlies our ability to locate sound sources in the environment, our appreciation of music, and our ability to communicate. Participants in the National Academy of Sciences colloquium on Auditory Neuroscience: Development, Transduction, and ...
Hudspeth, A. J., Konishi, Masakazu
core  

Investigating the expression profiles of cysteine string proteins (CSPs) in cochlear tissue

Journal of Otology
Objective: This study aims to explore the expression patterns of cysteine string protein alpha (CSPα) and cysteine string protein beta (CSPβ) in the mammalian inner ear, with an emphasis on their temporal dynamics during the developmental stages of C57BL/
Shili Zhang, Caiji Wang, Yuehua Qiao, Xi Shi   +3 more
doaj  

Clustered Ca2+ Channels Are Blocked by Synaptic Vesicle Proton Release at Mammalian Auditory Ribbon Synapses

Cell Reports, 2018
Summary: A Ca2+ current transient block (ICaTB) by protons occurs at some ribbon-type synapses after exocytosis, but this has not been observed at mammalian hair cells.
Philippe F.Y. Vincent, Soyoun Cho, Margot Tertrais, Yohan Bouleau, Henrique von Gersdorff, Didier Dulon   +5 more
doaj  

Defective Tmprss3-Associated Hair Cell Degeneration in Inner Ear Organoids

Stem Cell Reports, 2019
Summary: Mutations in the gene encoding the type II transmembrane protease 3 (TMPRSS3) cause human hearing loss, although the underlying mechanisms that result in TMPRSS3-related hearing loss are still unclear.
Pei-Ciao Tang, Alpha L. Alex, Jing Nie, Jiyoon Lee, Adam A. Roth, Kevin T. Booth, Karl R. Koehler, Eri Hashino, Rick F. Nelson   +8 more
doaj  

Noise-Induced Hearing Loss: Overview and Future Prospects for Research on Oxidative Stress. [PDF]

Int J Mol Sci
Kitama T, Nishiyama T, Hosoya M, Shimanuki MN, Ueno M, You F, Ozawa H, Oishi N.   +7 more
europepmc   +1 more source

Recent advances on the mechanism of acupuncture in the treatment of subjective tinnitus. [PDF]

Front Syst Neurosci
Shi F, Ye Z, Zha B, Wu W, Zhang Y, Yu L, Liu W, Rong Y, Yang J.   +8 more
europepmc   +1 more source

Platinum-induced ototoxicity and hearing impairment in children and adolescents. [PDF]

Drugs Context
Romano A, Attinà G, Maurizi P, Talloa D, Mastrangelo S, Ruggiero A.   +5 more
europepmc   +1 more source

Upregulated Expression and Shifted Distribution of Melatonin and Its Synthesizing Enzymes From Postnatal to Young Adult Rat Cochleae. [PDF]

Dev Neurobiol
Orsolic M, Diensthuber M, Stöver T, Geißler C.   +3 more
europepmc   +1 more source