Results 161 to 170 of about 119,470 (327)
Stem-cell therapy for hearing loss: are we there yet?
Brazilian Journal of Otorhinolaryngology, 2019 Introduction: Mammalian hair cells and auditory neurons do not show regenerative capacity. Hence, damage to these cell types is permanent and leads to hearing loss. However, there is no treatment that re-establishes auditory function.
Luiz Gustavo Dufner-Almeida +5 more
doaj
Auditory neuroscience: Development, transduction and integration [PDF]
, 2000 Hearing underlies our ability to locate sound sources in the environment, our appreciation of music, and our ability to communicate. Participants in the National Academy of Sciences colloquium on Auditory Neuroscience: Development, Transduction, and ...
Hudspeth, A. J., Konishi, Masakazu
core
The Significance of Subperiosteal Abscess Volume in Acute Mastoiditis
The Laryngoscope, EarlyView.Both needle aspiration and I&D are safe methods to reduce the infective and inflammatory load of subperiosteal abscess due to acute mastoiditis and provide pus for culture. Higher volumes (~3 cm3 and more) should be managed initially with cortical mastoidectomy since the risk of no improvement following needle aspiration or I&D is higher.
Rani Abu‐Eta +5 more
wiley +1 more source
The Laryngoscope, EarlyView.While both cochlear implants and bone conduction implants improve tinnitus symptoms, cochlear implants provide significantly greater suppression across multiple tinnitus severity measures and a higher cure rate, positioning it as the preferred option for tinnitus management in asymmetric hearing loss and single‐sided deafness patients.
Jae Sang Han +5 more
wiley +1 more source
Long‐Term Cochlear Implant Sensitivity in Patients With Far Advanced Otosclerosis
The Laryngoscope, EarlyView.This study aimed to evaluate mid‐ and long‐term cochlear implant fitting in otosclerosis patients compared to a control group. It suggested significant tissue remodeling at the cochlear apex in otosclerosis patients, likely increasing resistance to electrical currents delivered by the implant.
Raphaële Quatre +3 more
wiley +1 more source
Innervation of Cochlear Hair Cells by Human Induced Pluripotent Stem Cell-Derived Neurons In Vitro
Stem Cells International, 2016 Induced pluripotent stem cells (iPSCs) may serve as an autologous source of replacement neurons in the injured cochlea, if they can be successfully differentiated and reconnected with residual elements in the damaged auditory system.
Niliksha Gunewardene +3 more
doaj +1 more source
Quantitative Proteomics of Cochlear Tissues: Bilateral Comparisons in Guinea Pigs and Rats
PROTEOMICS, EarlyView.ABSTRACT The cochlea, an incredibly sensitive sensory system, detects sound waves and converts them into electrical signals the brain recognizes as sound. Damage to cochlear hair cells can release proteins, triggering biological responses that may impair hearing.
Motahare Khorrami +3 more
wiley +1 more source
Update on Gene Therapy in the Treatment of Hereditary Hearing Loss
Sensory Neuroscience, EarlyView.Gene therapy is a promising therapeutic approach for genetic disorders, including three major gene therapy strategies: gene replacement, gene suppression, and gene editing. After transmitting genes to the inner ear through appropriate pathways, repair the cochlea in order to achieve the goal of treating hereditary hearing loss.
Weiwei He +7 more
wiley +1 more source
Sensory Neuroscience, EarlyView.ABSTRACT Effective rehabilitation techniques for neglect are lacking. The aim of this article is to propose a method in which a comfortable sound that is convenient to the hearing of patients with stroke will be delivered to the affected side's ear via a head phone for 6 h a day divided in 3 sessions (2 h each) per day, for 2 weeks to improve neglect ...
Auwal Abdullahi +2 more
wiley +1 more source
Small, EarlyView.This review presents a detailed overview of clinically approved nanoparticle therapeutics, classifying them by type and discussing their unique advantages in drug delivery. It highlights regulatory challenges across global markets and emphasizes the need for adaptive approval pathways.
Nimeet Desai +5 more
wiley +1 more source