Results 11 to 20 of about 463,740 (300)
Reprogramming of the cochlea with hair-cell-specific transcription factors such as ATOH1 has been proposed as a potential therapeutic strategy for hearing loss.
Amrita A Iyer +15 more
doaj +1 more source
Hair cell maturation is differentially regulated along the tonotopic axis of the mammalian cochlea [PDF]
Sound amplification within the mammalian cochlea depends upon specialized hair cells, the outer hair cells (OHCs), which possess both sensory and motile capabilities.
Ceriani, Federico +7 more
core +2 more sources
Hair Cell Generator Potentials [PDF]
A technique is introduced using a piezoelectric device to stimulate hair cells of a molluscan statocyst while recording their responses intracellularly. Statocyst displacements produced with the technique are calibrated with stroboscopic photography. Properties of the hair cells' response to currents and mechanical stimulation are studied.
D L, Alkon, A, Bak
openaire +2 more sources
Stepwise fate conversion of supporting cells to sensory hair cells in the chick auditory epithelium
Summary: In contrast to mammals, the avian cochlea, specifically the basilar papilla, can regenerate sensory hair cells, which involves fate conversion of supporting cells to hair cells. To determine the mechanisms for converting supporting cells to hair
Mami Matsunaga +7 more
doaj +1 more source
Hair cell ribbon synapses [PDF]
Hearing and balance rely on the faithful synaptic coding of mechanical input by the auditory and vestibular hair cells of the inner ear. Mechanical deflection of their stereocilia causes the opening of mechanosensitive channels, resulting in hair cell depolarization, which controls the release of glutamate at ribbon-type synapses.
Tobias, Moser +2 more
openaire +2 more sources
Hair Follicle Stem Cells [PDF]
The workshop on Hair Follicle Stem Cells brought together investigators who have used a variety of approaches to try to understand the biology of follicular epithelial stem cells, and the role that these cells play in regulating the hair cycle.
Lavker, Robert M +11 more
openaire +3 more sources
Hair cell afferent synapses [PDF]
This review will cover advances in the study of hair cell afferent synaptic function occurring between 2005 and 2008. During this time, capacitance measurements of vesicular fusion have continued to be refined, optical methods have added insights regarding vesicle trafficking, and paired intracellular recordings have established the transfer function ...
Elisabeth, Glowatzki +2 more
openaire +2 more sources
Pattern formation in the basilar papilla: evidence for cell rearrangement. [PDF]
The avian basilar papilla is composed of hair and supporting cells arranged in a regular pattern in which the hair cells are surrounded and isolated from each other by supporting cell processes.
Goodyear, Richard, Richardson, Guy
core +2 more sources
Mutations in ap1b1 Cause Mistargeting of the Na(+)/K(+)-ATPase Pump in Sensory Hair Cells. [PDF]
The hair cells of the inner ear are polarized epithelial cells with a specialized structure at the apical surface, the mechanosensitive hair bundle.
Clemens Grisham, Rachel +4 more
core +2 more sources
Beyond generalized hair cells: Molecular cues for hair cell types [PDF]
Basic helix-loop-helix (bHLH) transcription factors (TFs) are crucial for inner ear neurosensory development. The proneural TF Atoh1 regulates the differentiation of hair cells (HCs) whereas Neurog1 and Neurod1 regulate specification and differentiation of neurons, respectively, but also affect HC development.
Israt, Jahan +3 more
openaire +2 more sources

