Results 21 to 30 of about 5,127,301 (263)

Hair Graying Regulators Beyond Hair Follicle

Frontiers in Physiology, 2022
Hair graying is an interesting physiological alteration associated with aging and certain diseases. The occurrence is due to depigmentation of the hair caused by depletion and dysfunction of melanocyte stem cells (MeSCs).
Jing Chen, Jing Chen, Yixin Zheng, Chen Hu, Xuexiao Jin, Xiaoping Chen, Ying Xiao, Chaochen Wang, Chaochen Wang   +8 more
doaj   +1 more source

Molecular biology of hearing [PDF]

, 2012
The inner ear is our most sensitive sensory organ and can be subdivided into three functional units: organ of Corti, stria vascularis and spiral ganglion.
Diensthuber, M, Stöver, T, Diensthuber, Marc, Stöver, Timo   +3 more
core   +1 more source

Numb is not a critical regulator of Notch-mediated cell fate decisions in the developing chick inner ear. [PDF]

, 2015
The Notch signaling pathway controls differentiation of hair cells and supporting cells in the vertebrate inner ear. Here, we have investigated whether Numb, a known regulator of Notch activity in Drosophila, is involved in this process in the embryonic ...
Mark eEddison, Weber, SJ, Ariza-McNaughton, L, Julian eLewis, Nicolas eDaudet, Lewis, J, Sara Johanna Weber, Eddison, M, Daudet, N, Linda eAriza-McNaughton, Sara J. Weber, Mark Eddison, Linda Ariza-McNaughton, Julian Lewis, Nicolas Daudet   +14 more
core   +1 more source

Thyroxine differentially modulates the peripheral clock: lessons from the human hair follicle [PDF]

, 2015
The human hair follicle (HF) exhibits peripheral clock activity, with knock-down of clock genes (BMAL1 and PER1) prolonging active hair growth (anagen) and increasing pigmentation.
Haslam, Iain S., Iain S Haslam, Jonathan A Hardman, Hardman, Jonathan A, Bessam Farjo (714627), Farjo, Bessam, Nilofer Farjo (714626), Nilofer Farjo, Jonathan A. Hardman (714625), Ralf Paus, Farjo, Nilofer, Bessam Farjo, Iain S. Haslam (452871), Haslam, Iain S, Hardman, Jonathan A., Paus, Ralf, Ralf Paus (261703), Farjo Bessam, Hardman Jonathan A., Haslam Iain S., Paus Ralf, Farjo Nilofer   +21 more
core   +3 more sources

Hair bundles of cochlear outer hair cells are shaped to minimize their fluid-dynamic resistance

Scientific Reports, 2017
The mammalian sense of hearing relies on two types of sensory cells: inner hair cells transmit the auditory stimulus to the brain, while outer hair cells mechanically modulate the stimulus through active feedback.
Nikola Ciganović, Amanuel Wolde-Kidan, Tobias Reichenbach   +2 more
doaj   +1 more source

Insight into the early steps of root hair formation revealed by the procuste1 cellulose synthase mutant of Arabidopsis thaliana [PDF]

, 2008
Background: formation of plant root hairs originating from epidermal cells involves selection of a polar initiation site and production of an initial hair bulge which requires local cell wall loosening. In Arabidopsis the polar initiation site is located
Singh, Sunil K., Singh, Manoj, Marchant, Alan, Fischer, Urs, Grebe, Markus, Singh, Sunil, Grebe, Markus,, Alan Marchant, Singh, Sunil,, Urs Fischer, Manoj Singh, Sunil K Singh, Markus Grebe, Singh, Manoj,, Marchant, Alan,, Swedish University of Agricultural Sciences., Singh, Sunil Kumar,, Fischer, Urs,   +17 more
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Hair Follicle Generation by Injections of Adult Human Follicular Epithelial and Dermal Papilla Cells into Nude Mice

Cell Journal, 2017
Objective Dermal papilla and hair epithelial stem cells regulate hair formation and the growth cycle. Damage to or loss of these cells can cause hair loss.
Mohammadali Nilforoushzadeh, Elham Rahimi Jameh, Fariba Jaffary, Ehsan Abolhasani, Gelavizh Keshtmand, Hajar Zarkob, , Parvaneh Mohammadi, Nasser Aghdami   +7 more
doaj   +1 more source

Activated notch causes deafness by promoting a supporting cell phenotype in developing auditory hair cells. [PDF]

PLoS ONE, 2014
To determine whether activated Notch can promote a supporting cell fate during sensory cell differentiation in the inner ear.An activated form of the Notch1 receptor (NICD) was expressed in early differentiating hair cells using a Gfi1-Cre mouse allele ...
Grace Savoy-Burke, Felicia A Gilels, Wei Pan, Diana Pratt, Jianwen Que, Lin Gan, Patricia M White, Amy E Kiernan   +7 more
doaj   +1 more source

The role of epigenetic modifications in sensory hair cell development, survival, and regulation

Frontiers in Cellular Neuroscience, 2023
The cochlea is the sensory organ in the periphery, and hair cells are its main sensory cells. The development and survival of hair cells are highly controlled processes.
Ying Xiao, Dan Li
doaj   +1 more source

Release and elementary mechanisms of nitric oxide in hair cells

, 2010
The enzyme nitric oxide (NO) synthase, that produces the signaling molecule NO, has been identified in several cell types in the inner ear. However, it is unclear whether a measurable quantity of NO is released in the inner ear to confer specific ...
Song, Haitao, Smith, Peter J S, Yamoah, Ebenezer N, Lv, Ping, Eastwood, Emily, Yevgeniy, Petrov Y, Mu, Karen, Levic, Snezana, Wei, Dongguang, Zhu, Jun, Kim, Hyo Jeong, Choong-Ryoul, Sihn, Rodriguez-Contreras, Adrian   +12 more
core   +1 more source