Results 21 to 30 of about 227,838 (314)

Differentiation and transplantation of human induced pluripotent stem cell-derived otic epithelial progenitors in mouse cochlea

open access: yesStem Cell Research & Therapy, 2018
Background Inner ear hair cells as mechanoreceptors are extremely important for hearing. Defects in hair cells are a major cause of deafness. Induced pluripotent stem cells (iPSCs) are promising for regenerating inner ear hair cells and treating hearing ...
Jianling Chen   +7 more
doaj   +1 more source

RIM-Binding Proteins Are Required for Normal Sound-Encoding at Afferent Inner Hair Cell Synapses

open access: yesFrontiers in Molecular Neuroscience, 2021
The afferent synapses between inner hair cells (IHC) and spiral ganglion neurons are specialized to faithfully encode sound with sub-millisecond precision over prolonged periods of time.
Stefanie Krinner   +10 more
doaj   +1 more source

Supporting cells remove and replace sensory receptor hair cells in a balance organ of adult mice

open access: yeseLife, 2017
Vestibular hair cells in the inner ear encode head movements and mediate the sense of balance. These cells undergo cell death and replacement (turnover) throughout life in non-mammalian vertebrates.
Stephanie A Bucks   +5 more
doaj   +1 more source

Hair follicle associated pluripotent (HAP) stem cells jump from transplanted whiskers to pelage follicles and stimulate hair growth

open access: yesScientific Reports, 2022
Stimulation of hair growth in hair loss has been a difficult goal to achieve. Hair follicle-associated pluripotent (HAP) stem cells express nestin and have been shown to differentiate to multiple cell types including keratinocytes, neurons, beating ...
Koya Obara   +7 more
doaj   +1 more source

Hair Cell Generator Potentials [PDF]

open access: yesThe Journal of General Physiology, 1973
A technique is introduced using a piezoelectric device to stimulate hair cells of a molluscan statocyst while recording their responses intracellularly. Statocyst displacements produced with the technique are calibrated with stroboscopic photography. Properties of the hair cells' response to currents and mechanical stimulation are studied.
D L, Alkon, A, Bak
openaire   +2 more sources

Hair Graying Regulators Beyond Hair Follicle

open access: yesFrontiers in Physiology, 2022
Hair graying is an interesting physiological alteration associated with aging and certain diseases. The occurrence is due to depigmentation of the hair caused by depletion and dysfunction of melanocyte stem cells (MeSCs).
Jing Chen   +8 more
doaj   +1 more source

Magnetic actuation of hair cells [PDF]

open access: yesApplied Physics Letters, 2011
The bullfrog sacculus contains mechanically sensitive hair cells whose stereociliary bundles oscillate spontaneously when decoupled from the overlying membrane. Steady-state offsets on the resting position of a hair bundle can suppress or modulate this native motility.
David, Rowland   +4 more
openaire   +2 more sources

Hair bundles of cochlear outer hair cells are shaped to minimize their fluid-dynamic resistance

open access: yesScientific Reports, 2017
The mammalian sense of hearing relies on two types of sensory cells: inner hair cells transmit the auditory stimulus to the brain, while outer hair cells mechanically modulate the stimulus through active feedback.
Nikola Ciganović   +2 more
doaj   +1 more source

Hair Follicle Generation by Injections of Adult Human Follicular Epithelial and Dermal Papilla Cells into Nude Mice

open access: yesCell Journal, 2017
Objective Dermal papilla and hair epithelial stem cells regulate hair formation and the growth cycle. Damage to or loss of these cells can cause hair loss.
Mohammadali Nilforoushzadeh   +7 more
doaj   +1 more source

Active hair bundle movements in auditory hair cells [PDF]

open access: yesThe Journal of Physiology, 2006
The frequency selectivity of mammalian hearing depends on not only the passive mechanics of the basilar membrane but also an active amplification of the mechanical stimulus by the cochlear hair cells. The common view is that amplification stems from the somatic motility of the outer hair cells (OHCs), changes in their length impelled by voltage ...
openaire   +2 more sources

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