Results 81 to 90 of about 5,127,301 (263)
FEBS Open Bio, EarlyView.Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar +11 more
wiley +1 more source
Neurotrophic Effects of Silibinin on Differentiation of Hair Follicle Stem Cells to Neurons [PDF]
Neurotrophic Effects of Silibinin on Differentiation of Hair Follicle Stem Cells to NeuronsAbstract Background and Objectives: Hair Follicle Bulge region due to its availability and abundance is one of the areas which is easily accessible to Multi-potent
آسالگو, سارا +5 more
core
Molecular expression associated with vibrissa follicle development and differentiation [PDF]
, 2006 The hair follicle is a complex mini-organ formed as a result of epithelial mesenchymal interactions, provided by three different stem cell sources: epithelial, neural crest and mesenchymal.
Hammond, Nigel L.
core
Auxin transport through non-hair cells sustains root-hair development [PDF]
, 2009 The plant hormone auxin controls root epidermal cell development in a concentration-dependent manner. Root hairs are produced on a subset of epidermal cells as they increase in distance from the root tip.
Leyser, H.M.O +23 more
core +2 more sources
A minimal cellulosome‐like system in Cellulosilyticum lentocellum
FEBS Open Bio, EarlyView.Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source
A Review of Gene Delivery and Stem Cell Based Therapies for Regenerating Inner Ear Hair Cells
Journal of Functional Biomaterials, 2011 Sensory neural hearing loss and vestibular dysfunction have become the most common forms of sensory defects, affecting millions of people worldwide. Developing effective therapies to restore hearing loss is challenging, owing to the limited regenerative ...
Michael S. Detamore +2 more
doaj +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Identification and characterisation of gene regulation by the POU4F3 (BRN-3C) transcription factor in the inner ear [PDF]
, 2010 Hair cells are the mechanosensory cells of the inner ear whose loss causes irreversible hearing loss in mammals. POU4F3, a POU-domain transcription factor, is only expressed in hair cells in the inner ear and is essential for hair cell terminal ...
Tornari, C.
core
Cell Reports, 2017 Death of cochlear hair cells, which do not regenerate, is a cause of hearing loss in a high percentage of the population. Currently, no approach exists to obtain large numbers of cochlear hair cells.
Will J. McLean +7 more
doaj +1 more source
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
FEBS Open Bio, EarlyView.Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source