Results 61 to 70 of about 227,838 (314)

Hair follicle dermal cells: a morphological, behavioural and molecular study [PDF]

, 1995
Anatomy and smooth muscle a-actin expression in hair follicles from a variety of animal species (Mink, Polecat, Meerkat, Grey squirrel and stoat) was investigated. Smooth muscle ɑ-actin expression was related to follicle activity. Expression was greatest
Sleeman, Matthew Alexander, Sleeman, M
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Regenerative potential of CD200- subpopulations of hair follicle bulge

Frontiers in Cell and Developmental Biology
The hair follicle bulge is regarded as a reservoir of epithelial stem cells for hair regeneration. Hair follicle bulge cells are generally characterized by CD200 expression.
Ting Sun, Ting Sun, Sayuri Hamano, Jing Chen, Lichen Ling, Jinran Lin, Lei Yan, Lei Yan, Tatsuto Kageyama, Tatsuto Kageyama, Fuyue Wu, Zheng Lin Tan, Wenyu Wu, Junji Fukuda, Junji Fukuda   +14 more
doaj   +1 more source

Effects of DAPT and Atoh1 overexpression on hair cell production and hair bundle orientation in cultured Organ of Corti from neonatal rats.

PLoS ONE, 2011
BackgroundIn mammals, hair cells do not undergo spontaneous regeneration when they are damaged and result in permanent hearing loss. Previous studies in cultured Organ of Corti dissected from neonatal animals have shown that both DAPT (r-secretase ...
Li-Dong Zhao, Wei-Wei Guo, Chang Lin, Li-Xian Li, Jian-He Sun, Nan Wu, Li-Li Ren, Xin-Xin Li, Hui-Zhan Liu, Wie-Yen Young, Wei-Qiang Gao, Shi-Ming Yang   +11 more
doaj   +1 more source

Characterization of Hair Cell-Like Cells Converted From Supporting Cells After Notch Inhibition in Cultures of the Organ of Corti From Neonatal Gerbils

Frontiers in Cellular Neuroscience, 2018
The senses of hearing and balance depend upon hair cells, the sensory receptors of the inner ear. Hair cells transduce mechanical stimuli into electrical activity.
Yi Li, Yi Li, Shuping Jia, Huizhan Liu, Tomoko Tateya, Weiwei Guo, Shiming Yang, Kirk W. Beisel, David Z. Z. He   +8 more
doaj   +1 more source

Protective Effect of Hydroxygenkwanin against Hair Graying Induced by X-Ray Irradiation and Repetitive Plucking

JID Innovations, 2022
Hair graying in mice is caused by various injuries such as X-ray radiation and repeated plucking that ultimately damage melanocytes and their stem cells (melanocyte stem cells).
Nobuhiko Taguchi, Ryosuke Kitai, Takuya Ando, Toshihiro Nishimura, Hitomi Aoki, Takahiro Kunisada   +5 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Cell-Specific Transcriptome Analysis Shows That Adult Pillar and Deiters' Cells Express Genes Encoding Machinery for Specializations of Cochlear Hair Cells

Frontiers in Molecular Neuroscience, 2018
The mammalian auditory sensory epithelium, the organ of Corti, is composed of hair cells and supporting cells. Hair cells contain specializations in the apical, basolateral and synaptic membranes.
Huizhan Liu, Lei Chen, Lei Chen, Kimberlee P. Giffen, Sean T. Stringham, Yi Li, Paul D. Judge, Kirk W. Beisel, David Z. Z. He   +8 more
doaj   +1 more source

The challenge of hair cell regeneration [PDF]

Experimental Biology and Medicine, 2010
Sensory hair cells of the inner ear are responsible for translating auditory or vestibular stimuli into electrical energy that can be perceived by the nervous system. Although hair cells are exquisitely mechanically sensitive, they can be easily damaged by excessive stimulation by ototoxic drugs and by the effects of aging.
openaire   +2 more sources

Hair cell afferent synapses [PDF]

Current Opinion in Neurobiology, 2008
This review will cover advances in the study of hair cell afferent synaptic function occurring between 2005 and 2008. During this time, capacitance measurements of vesicular fusion have continued to be refined, optical methods have added insights regarding vesicle trafficking, and paired intracellular recordings have established the transfer function ...
Elisabeth, Glowatzki, Lisa, Grant, Paul, Fuchs   +2 more
openaire   +2 more sources