Results 21 to 30 of about 612,705 (204)

Traditional Chinese Medicine Shi-Bi-Man regulates lactic acid metabolism and drives hair follicle stem cell activation to promote hair regeneration

Chinese Medicine, 2023
Background As a supplement for promoting hair health, Shi-Bi-Man (SBM) is a prescription comprising various traditional Chinese medicines. Though SBM has been reported to promote hair regeneration, its molecular mechanism remains unclear.
Haojie Du, Tao Zhang, Qiao Wang, Xinran Cao, Huiwen Zheng, Jiabin Li, Jianxia Zhu, Jiao Qu, Lehang Guo, Yang Sun   +9 more
doaj   +1 more source

Prolactin delays hair regrowth in mice [PDF]

, 2006
Mammalian hair growth is cyclic, with hair-producing follicles alternating between active (anagen) and quiescent (telogen) phases. The timing of hair cycles is advanced in prolactin receptor (PRLR) knockout mice, suggesting that prolactin has a role in ...
Ashby, M.G., Nixon, A.J., Pearson, A.J., Ormandy, C.J., Blazek, K., Wilkins, Richard J., Craven, A.J.   +6 more
core   +1 more source

Type 2 Diabetic Mellitus Inhibits Skin Renewal through Inhibiting WNT-Dependent Lgr5+ Hair Follicle Stem Cell Activation in C57BL/6 Mice

Journal of Diabetes Research, 2022
Background. Hair follicles are important accessory organs of the skin, and it is important for skin renewal and performs variety of important functions. Diabetes can cause several dermatoses; however, its effect on hair follicles is unclear.
Minghui Wang, Shangsheng Yao, Dehua He, Mulan Qahar, Jinqing He, Meifang Yin, Jun Wu, Guang Yang   +7 more
doaj   +1 more source

A combination therapy for androgenic alopecia based on quercetin and zinc/copper dual-doped mesoporous silica nanocomposite microneedle patch

Bioactive Materials, 2023
A nanocomposite microneedle (ZCQ/MN) patch containing copper/zinc dual-doped mesoporous silica nanoparticles loaded with quercetin (ZCQ) was developed as a combination therapy for androgenic alopecia (AGA).
Zhaowenbin Zhang, Wenbo Li, Di Chang, Ziqin Wei, Endian Wang, Jing Yu, Yuze Xu, Yumei Que, Yanxin Chen, Chen Fan, Bing Ma, Yanling Zhou, Zhiguang Huan, Chen Yang, Feng Guo, Jiang Chang   +15 more
doaj   +1 more source

Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing

Nature Communications, 2018
On wounding, scar formation in mammals arises causing no hair follicle regeneration, but it is unclear if scarring precludes regeneration. Here, the authors show that if Sonic hedgehog signaling is activated in the wound, an inductive dermal niche forms,
Chae Ho Lim, Qi Sun, Karan Ratti, Soung-Hoon Lee, Ying Zheng, Makoto Takeo, Wendy Lee, Piul Rabbani, Maksim V. Plikus, Jason E. Cain, David H. Wang, D. Neil Watkins, Sarah Millar, M. Mark Taketo, Peggy Myung, George Cotsarelis, Mayumi Ito   +16 more
doaj   +1 more source

Augmenting endogenous wnt signaling improves skin wound healing [PDF]

, 2013
Wnt signaling is required for both the development and homeostasis of the skin, yet its contribution to skin wound repair remains controversial. By employing Axin2(LacZ/+) reporter mice we evaluated the spatial and temporal distribution patterns of Wnt ...
Manzano Wilfred R., Fang Mark Y., Girija R Dhamdhere, Anthony E. Oro, Bo Liu, Fang, Mark Y, Whyte, Jemima L., Helms Jill A., Wilfred R. Manzano, Nick D. Evans (474290), Manzano, Wilfred R, Howard Y. Chang (215450), Smith, Andrew A, Manzano, Wilfred R., Whyte, Jemima L, Jemima L. Whyte (474287), Nick D Evans, Helms, Jill A., Andrew A Smith, Anthony E Oro, Andrew A. Smith (474288), Oro Anthony E., Chang, Howard Y., Jemima L Whyte, Liu Bo, Howard Y Chang, Dhamdhere, Girija R, Evans Nick D., Evans, Nick D., Wilfred R. Manzano (474289), Oro, Anthony E., Nick D. Evans¤a, Smith Andrew A., Whyte Jemima L., Liu, Bo, Mark Y. Fang (474292), Wilfred R Manzano, Jill A. Helms (25398), Fang, Mark Y., Smith, Andrew A., Andrew A. Smith, Evans, Nick D, Helms, Jill A, Girija R. Dhamdhere (474291), Girija R. Dhamdhere, Jill A Helms, Mark Y. Fang¤b, Anthony E. Oro (474293), Jill A. Helms, Dhamdhere, Girija R., Mark Y Fang, Chang, Howard Y, Chang Howard Y., Jemima L. Whyte, Oro, Anthony E, Howard Y. Chang, Bo Liu (127343), Dhamdhere Girija R.   +57 more
core   +2 more sources

Hair Regeneration Methods Using Cells Derived from Human Hair Follicles and Challenges to Overcome

Cells
The hair follicle is a complex of mesenchymal and epithelial cells acquiring different properties and characteristics responsible for fulfilling its inductive and regenerative role.
Ons Ben Hamida, Moon Kyu Kim, Young Kwan Sung, Min Kyu Kim, Mi Hee Kwack   +4 more
doaj   +1 more source

Morphogenesis, Growth Cycle and Molecular Regulation of Hair Follicles

Frontiers in Cell and Developmental Biology, 2022
As one of the main appendages of skin, hair follicles play an important role in the process of skin regeneration. Hair follicle is a tiny organ formed by the interaction between epidermis and dermis, which has complex and fine structure and periodic ...
Xiangyu Lin, Liang Zhu, Jing He
doaj   +1 more source

Dermal T cell immunity and key regulatory signaling pathways: Implications in immune-mediated alopecia and hair regeneration

Genes and Diseases
Mammalian hair follicles undergo periodic regeneration, with recent research highlighting the immunological niche as a critical regulator of stem cell activity and hair follicle regeneration.
Nana Tao, Qingru Sun, Yuyuan Ying, Yitao Wang, Jianli Gao   +4 more
doaj   +1 more source

Jagged1 and Epidermal Growth Factor Promoted Androgen-Suppressed Mouse Hair Growth In Vitro and In Vivo

Frontiers in Pharmacology, 2020
Recent studies have reported that T-reg cells are intimately linked with hair follicles in a stage-dependent manner and play an important role in hair follicle cycling and regeneration in murine skin.
Yufeng Lin, Canying Liu, Xiaoshu Zhan, Xiaoshu Zhan, Bingyun Wang, Kui Li, Kui Li, Julang Li   +7 more
doaj   +1 more source