Results 1 to 10 of about 5,630,806 (253)

Hair Follicle Stem Cell Isolation and Expansion [PDF]

Bio-Protocol, 2018
Stem cells are widely used for numerous clinical applications including limbal stem cell deficiency. Stem cell derived from the bulge region of the hair follicle have the ability to differentiate into a variety of cell types including interfollicular ...
Mindy Call, Ewa Meyer, Winston Kao, Friedrich Kruse, Ursula Schloetzer-Schredhardt   +4 more
doaj   +5 more sources

Hair Follicle Development in Mouse Pluripotent Stem Cell-Derived Skin Organoids [PDF]

Cell Reports, 2018
Summary: The mammalian hair follicle arises during embryonic development from coordinated interactions between the epidermis and dermis. It is currently unclear how to recapitulate hair follicle induction in pluripotent stem cell cultures for use in ...
Jiyoon Lee, Robert Bӧscke, Pei-Ciao Tang, Byron H. Hartman, Stefan Heller, Karl R. Koehler   +5 more
doaj   +4 more sources

Disrupted cholesterol biosynthesis and hair follicle stem cell impairment in the onset of alopecia. [PDF]

PLoS ONE
BackgroundHair follicle cycle and the functioning of stem cells in alopecia are influenced by the suppression of cholesterol synthesis and the accumulation of sterol intermediates.ObjectiveThis investigation aims to elucidate the regulatory function of ...
Leemon Nikhila, Suresh Surya, Shahul Hameed Najeeb, Thankachan Mangalathettu Binumon, Aayush Gupta, Sandeep Gopalakrishnan, Mahsa Dabagh, Parameswara Panicker Sreejith   +7 more
doaj   +2 more sources

Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt pathway, Growth-Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development

Cells, 2019
The use of stem cells has been reported to improve hair regrowth in several therapeutic strategies, including reversing the pathological mechanisms, that contribute to hair loss, regeneration of hair follicles, or creating hair using the tissue ...
Pietro Gentile, Simone Garcovich
doaj   +3 more sources

Autophagy induces hair follicle stem cell activation and hair follicle regeneration by regulating glycolysis [PDF]

Cell & Bioscience
Background Hair follicle stem cells (HFSCs) typically remain quiescent and are activated only during the transition from telogen to anagen to ensure that the hair follicle enters a new cycle.
Pingping Sun, Zhan Wang, Sixiao Li, Jiajing Yin, Yuyang Gan, Shizhao Liu, Zhen Lin, Hailin Wang, Zhexiang Fan, Qian Qu, Zhiqi Hu, Kaitao Li, Yong Miao   +12 more
doaj   +2 more sources

Dermal PapillaCell-Derived Exosomes Regulate Hair Follicle Stem Cell Proliferation via LEF1 [PDF]

International Journal of Molecular Sciences, 2023
Xinsheng Wu, Jiali Li, JiaWei Cai
exaly   +2 more sources

The anti‐apoptotic Bcl‐2 protein regulates hair follicle stem cell function [PDF]

EMBO Reports, 2021
Hamid Kashkar, Catherin Niemann
exaly   +2 more sources

The dermal sheath: An emerging component of the hair follicle stem cell niche [PDF]

Experimental Dermatology, 2021
Michael Rendl, Nicholas J Heitman
exaly   +2 more sources

A Hairy Cituation – PADIs in Regeneration and Alopecia

Frontiers in Cell and Developmental Biology, 2021
In this Review article, we focus on delineating the expression and function of Peptidyl Arginine Delminases (PADIs) in the hair follicle stem cell lineage and in inflammatory alopecia. We outline our current understanding of cellular processes influenced
Kim Vikhe Patil, Kylie Hin-Man Mak, Maria Genander   +2 more
doaj   +1 more source

Epidermal Stem Cells in Hair Follicle Cycling and Skin Regeneration: A View From the Perspective of Inflammation

Frontiers in Cell and Developmental Biology, 2020
There are many studies devoted to the role of hair follicle stem cells in wound healing as well as in follicle self-restoration. At the same time, the influence of the inflammatory cells on the hair follicle cycling in both injured and intact skin is ...
Elena I. Morgun, Ekaterina A. Vorotelyak
doaj   +1 more source