Results 11 to 20 of about 5,630,806 (253)

Hair follicle stem cells: Walking the maze

European Journal of Cell Biology, 2007
The discovery of epithelial stem cells (eSCs) in the bulge region of the outer root sheath of hair follicles in mice and man has encouraged research into utilizing the hair follicle as a therapeutic source of stem cells (SCs) for regenerative medicine, and has called attention to the hair follicle as a highly instructive model system for SC biology ...
Stephan, Tiede, Jennifer E, Kloepper, Enikö, Bodò, Sanjay, Tiwari, Charli, Kruse, Ralf, Paus   +5 more
core   +4 more sources

Platelet-derived growth factor signaling modulates adult hair follicle dermal stem cell maintenance and self-renewal

npj Regenerative Medicine, 2017
Hair loss: The protein that signals regeneration Signals from a protein that regulates cell division are essential to maintain the stem cells that regenerate hair follicles.
Raquel González, Garrett Moffatt, Andrew Hagner, Sarthak Sinha, Wisoo Shin, Waleed Rahmani, Andrew Chojnacki, Jeff Biernaskie   +7 more
doaj   +2 more sources

Thyroxine differentially modulates the peripheral clock: lessons from the human hair follicle [PDF]

, 2015
The human hair follicle (HF) exhibits peripheral clock activity, with knock-down of clock genes (BMAL1 and PER1) prolonging active hair growth (anagen) and increasing pigmentation.
Haslam, Iain S., Iain S Haslam, Jonathan A Hardman, Hardman, Jonathan A, Bessam Farjo (714627), Farjo, Bessam, Nilofer Farjo (714626), Nilofer Farjo, Jonathan A. Hardman (714625), Ralf Paus, Farjo, Nilofer, Bessam Farjo, Iain S. Haslam (452871), Haslam, Iain S, Hardman, Jonathan A., Paus, Ralf, Ralf Paus (261703)   +16 more
core   +5 more sources

Hair Follicle Stem Cells [PDF]

Journal of Investigative Dermatology Symposium Proceedings, 2003
The workshop on Hair Follicle Stem Cells brought together investigators who have used a variety of approaches to try to understand the biology of follicular epithelial stem cells, and the role that these cells play in regulating the hair cycle.
Lavker, Robert M, Sun, Tung-Tien, Oshima, Hideo, Barrandon, Yann, Akiyama, Masashi, Ferraris, Corinne, Chevalier, Genevieve, Favier, Bertrand, Jahoda, Colin a B, Dhouailly, Danielle, Panteleyev, Andrei A, Christiano, Angela M   +11 more
openaire   +4 more sources

Embryonic attenuated Wnt/β-catenin signaling defines niche location and long-term stem cell fate in hair follicle

eLife, 2015
Long-term adult stem cells sustain tissue regeneration throughout the lifetime of an organism. They were hypothesized to originate from embryonic progenitor cells that acquire long-term self-renewal ability and multipotency at the end of organogenesis ...
Zijian Xu, Wenjie Wang, Kaiju Jiang, Zhou Yu, Huanwei Huang, Fengchao Wang, Bin Zhou, Ting Chen   +7 more
doaj   +1 more source

miR-149-5p Regulates Goat Hair Follicle Stem Cell Proliferation and Apoptosis by Targeting the CMTM3/AR Axis During Superior-Quality Brush Hair Formation

Frontiers in Genetics, 2020
The Yangtze River Delta white goat is a unique goat species that can produce superior quality brush hair. CKLF-like MARVEL transmembrane domain-containing 3 (CMTM3), which influences the transcriptional activity of androgen receptor (AR), was identified ...
Jian Wang, Jian Wang, Jingwen Qu, Yongjun Li, Yongjun Li, Yunkui Feng, Jinliang Ma, Liuming Zhang, Changjiang Chu, Huiru Hu, Yanhu Wang, Dejun Ji   +11 more
doaj   +1 more source

Hair follicle associated pluripotent (HAP) stem cells jump from transplanted whiskers to pelage follicles and stimulate hair growth

Scientific Reports, 2022
Stimulation of hair growth in hair loss has been a difficult goal to achieve. Hair follicle-associated pluripotent (HAP) stem cells express nestin and have been shown to differentiate to multiple cell types including keratinocytes, neurons, beating ...
Koya Obara, Jose Reynoso, Yuko Hamada, Yusuke Aoki, Yutaro Kubota, Noriyuki Masaki, Yasuyuki Amoh, Robert M. Hoffman   +7 more
doaj   +1 more source

SnapShot: Hair Follicle Stem Cells

Cell, 2011
The hair follicle is an outstanding model for dissecting the biology of vertebrate stem cells. This SnapShot illustrates the current understanding of key aspects of hair follicle stem cell development and homeostasis.
Woo, Wei-Meng, Oro, Anthony E.
openaire   +2 more sources

Analysis of Sonic Hedgehog signalling pathway gene expression in Basal Cell Carcinoma and in GLII induced systems [PDF]

, 2007
PhDEmbryonic development is regulated by a number of signalling pathways, Which are critical for normal growth. Many of these genes then continue to play an important role in the regulation of cell growth and differentiation in adult.
Ikram, Mohammed S, Ikram, Mohammed. S.
core   +4 more sources

T-Regulating Hair Follicle Stem Cells [PDF]

Immunity, 2017
Regulatory T (Treg) cells are well known to modulate inflammatory responses. In a recent issue of Cell, Ali et al. (2017) reveal a function for Treg cells in stem cell maintenance by showing that skin-resident Foxp3+ Treg cells preferentially localize to the hair follicle stem cell (HFSC) niche to control HFSC-mediated hair regeneration.
Maria, Maryanovich, Paul S, Frenette
openaire   +2 more sources