Results 21 to 30 of about 5,630,806 (253)

Hair Follicle Stem Cells Derived from Single Rat Vibrissa via Organ Culture Reconstitute Hair Follicles in Vivo

Cell Transplantation, 2012
Hair follicle stem cells (HFSCs) are potentially useful for the treatment of skin injuries and diseases. To achieve clinical application, a prerequisite must be accomplished: harvesting enough HFSCs from limited skin biopsy.
Shoubing Zhang, Huimin Hu, Huishan Zhang, Shuang Liu, Shu Liu, Ying Zhang, Xiaohua Lei, Lina Ning, Yujing Cao, Enkui Duan   +9 more
doaj   +1 more source

Potential Natural Products Regulation of Molecular Signaling Pathway in Dermal Papilla Stem Cells

Molecules, 2023
Stem cells have demonstrated significant potential for tissue engineering and repair, anti-aging, and rejuvenation. Hair follicle stem cells can be found in the dermal papilla at the base of the follicle and the bulge region, and they have garnered ...
Zar Chi Soe, Zin Zin Ei, Kittichate Visuttijai, Pithi Chanvorachote   +3 more
doaj   +1 more source

The Pluripotency of Hair Follicle Stem Cells [PDF]

Cell Cycle, 2005
The hair follicle bulge area is an abundant, easily accessible source of actively growing, pluripotent adult stem cells. Nestin, a protein marker for neural stem cells, is also expressed in follicle stem cells as well as their immediate differentiated progeny.
openaire   +2 more sources

Hair Follicles, Stem Cells, and Skin Cancer.

Journal of Investigative Dermatology, 1993
Abbreviations: BCC, basal cell carcinoma; BP, benzo(a)pyrene; DMBA, 7,12-dimethylbenz(a)anthracene; LRCs, label-retaining cells; MCA, 3-methylcholanthrene; SCC, squamous cell carcinoma; TdR, [3H]thymidine; TPA, 12-O-tetradecanoylphorbol-13 ...
Miller, Stanley J., Sun, Tung-Tien, Lavker, Robert M.   +2 more
openaire   +2 more sources

Aging of hair follicle stem cells and their niches

BMB Reports, 2022
Hair follicles in the skin undergo cyclic rounds of regeneration, degeneration, and rest throughout life. Stem cells residing in hair follicles play a pivotal role in maintaining tissue homeostasis and hair growth cycles. Research on hair follicle aging and age-related hair loss has demonstrated that a decline in hair follicle stem cell (HFSC) activity
Hansaem Jang, Yemin Jo, Jung Hyun Lee, Sekyu Choi   +3 more
openaire   +3 more sources

Advances in stem cell-based therapy for hair loss [PDF]

CellR4, 2020
Hair loss is a quite common condition observed in both men and women. Pattern hair loss also known as androgenetic alopecia is the most common form of hair loss that is thought to affect up to 80% of Caucasian men and up to 40% of Caucasian women by age ...
A. Egger, M. Tomic-Canic, A. Tosti
doaj   +1 more source

The homing of exogenous hair follicle mesenchymal stem cells into hair follicle niches

JCI Insight, 2023
Hair loss is a debilitating condition associated with the depletion of dermal papilla cells (DPCs), which can be replenished by dermal sheath cells (DSCs). Hence, strategies aimed at increasing the populations of DPCs and DSCs hold promise for the treatment of hair loss.
Kaitao Li, Fang Liu, Ye He, Qian Qu, Pingping Sun, Lijuan Du, Jin Wang, Ruosi Chen, Yuyang Gan, Danlan Fu, Zhexiang Fan, Bingcheng Liu, Zhiqi Hu, Yong Miao   +13 more
openaire   +2 more sources

Sphingolipid metabolism orchestrates establishment of the hair follicle stem cell compartment. [PDF]

J Cell Biol
Sphingolipids serve as building blocks of membranes to ensure subcellular compartmentalization and facilitate intercellular communication. How cell type-specific lipid compositions are achieved and what is their functional significance in tissue ...
Peters F, Höfs W, Lee H, Brodesser S, Kruse K, Drexler HCA, Hu J, Raker VK, Lukas D, von Stebut E, Krönke M, Niessen CM, Wickström SA.   +12 more
europepmc   +2 more sources

Alkaline Ceramidase 1 Protects Mice from Premature Hair Loss by Maintaining the Homeostasis of Hair Follicle Stem Cells

Stem Cell Reports, 2017
Summary: Ceramides and their metabolites are important for the homeostasis of the epidermis, but much remains unknown about the roles of specific pathways of ceramide metabolism in skin biology.
Chih-Li Lin, Ruijuan Xu, Jae Kyo Yi, Fang Li, Jiang Chen, Evan C. Jones, Jordan B. Slutsky, Liqun Huang, Basil Rigas, Jian Cao, Xiaoming Zhong, Ashley J. Snider, Lina M. Obeid, Yusuf A. Hannun, Cungui Mao   +14 more
doaj   +1 more source

Spermidine Promotes Human Hair Growth and Is a Novel Modulator of Human Epithelial Stem Cell Functions [PDF]

, 2011
This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Sugawara Koji, Koji, Bakar, Mohd Hilmi Abu, Philpott, Michael P., Tiede Stephan, Stephan, Harrison, Wesley, Ramot Yuval, Yuval, Koji Sugawara, Wesley Harrison, Tiede, Stephan, Ramot, Y, Ramot Yuval, Paus Ralf, Paus, R, Pietilä, Marko, Tiede, S, Michael P Philpott, Harrison Wesley, Paus, Ralf, Philpott Michael P., Harrison, W, Marko Pietilä, Mohd Hilmi Abu Bakar, Abu Bakar Mohd Hilmi, Philpott, Michael P, Pietilä Marko, Abu Bakar, MH, Abu Bakar, Mohd Hilmi, Sugawara, K, Ralf Paus, Stephan Tiede, Yuval Ramot, Sugawara Koji, Bíró, Tamás, Sugawara, Koji, Tamás Bíró, Philpott, MP, Pietila, M, Michael P. Philpott, Ramot, Yuval, Tiede Stephan, Bíró Tamás, Biro, T   +41 more
core   +2 more sources