Results 41 to 50 of about 9,252,196 (204)
Sulfonate-isosteric replacement examined within heroin-hapten vaccine design
Bioorganic & Medicinal Chemistry Letters, 2020 Heroin overdose and addiction remain significant health and economic burdens in the world today costing billions of dollars annually. Moreover, only limited pharmacotherapeutic options are available for treatment of heroin addiction. In our efforts to combat the public health threat posed by heroin addiction, we have developed vaccines against heroin ...
Tyson F, Belz +6 more
openaire +3 more sources
Determinant moments for the design management occurrence in fashion industry [PDF]
, 2018 Design management has occupied a privileged place in debates related to the field of design and innovation in fashion industry. The apparel industry, in particular, presents a dynamic character, requiring constant updates on raw materials, changes in ...
Libânio, Cláudia de Souza +5 more
core +1 more source
Simple Synthesis of 17-β-O-hemisuccinate of Stanozolol for Immunoanalytical Methods
Molecules, 2020 The use of doping in sports is a global problem that affects athletes around the world. Among the different methods developed to detect doping agents in biological samples, there are antibody-based methods that need an appropriate hapten design. Steroids
Silvana Casati +2 more
doaj +1 more source
Comparison of Synthetic Methods and Identification of Several Artificial Antigens of Deoxynivalenol
Molecules, 2023 The purpose of this experiment was to study the design and modification of hapten molecules and artificial antigen molecules of deoxynivalenol (DON), and to compare the preparation and identification methods of four artificial antigens.
Li Han +6 more
doaj +1 more source
, 2017 The conventional hybridoma screening and subcloning process is generally considered to be one of the most critical steps in hapten-specific antibody production.
Schenk, J. A. +26 more
core +1 more source
Epitopes prediction for microcystin-LR by molecular docking
Ecotoxicology and Environmental Safety, 2021 Microcystin-LR (MC-LR) is one of the most worldwide harmful cyanobacterial toxins. A lots of antibodies against MC-LR have been generated and characterized. However, the knowledge about the epitopes of MC-LR was still limited. The objective of this study
Yuan Liu +10 more
doaj +1 more source
, 2018 We have developed an effective competitive electrochemical immunosensor assay based on hapten-grafted programmed probe (HGPP) as a corecognition element for highly sensitive and selective detection of acetamiprid.
Yuna Guo (780568) +6 more
core +1 more source
Molecules, 2019 The structure of hapten determines the performance of the antibody and the corresponding detection method. A new type of antigen was designed and synthesized to expose the spatial and characteristic structure of dinotefuran molecule, and a type of high ...
Fangfang Zhao, Jingkun Liu, Jinhui Luo
doaj +1 more source
Chemical strategies for triggering the immune response to the mycotoxin patulin
Scientific Reports, 2021 Mycotoxins represent a major concern for human and animal health because of their harmful effects and high occurrence in food and feed. Rapid immunoanalytical methods greatly contribute to strengthening the safety of our food supply by efficiently ...
Hadyn Duncan +5 more
doaj +1 more source
, 2019 While 7, 21 and 32 day sensitization periods yielded significant hapten-specific inflammation responses, the 32 day sensitization period showed the largest effect of prior sensitization.
J. Hostetter (7481327) +10 more
core +1 more source