Results 31 to 40 of about 9,252,196 (204)

Role of hydrophobic interaction in hapten-antibody binding [PDF]

open access: yes, 1977
The precipitation reaction of bovine serum albumin coupled with p-azophenylleucine with homologous antibody was inhibited by several structurally related haptens. The isobutyl group substituent on alpha-carbon atom of the leucine residue contributed more
Oda, Takuzo   +5 more
core   +1 more source

Critical by Design? [PDF]

open access: yes, 2022
In its constructive and speculative nature, design has the critical potential to reshape prevalent socio-material realities. At the same time, design is inevitably normative, if not often violent, as it stabilises the past, normalises the present, and ...

core   +2 more sources

Calix[n]arene-based immunogens: A new non-proteic strategy for anti-cocaine vaccine

open access: yesJournal of Advanced Research, 2022
Introduction: Cocaine use disorder is a significant public health issue without a current specific approved treatment. Among different approaches to this disorder, it is possible to highlight a promising immunologic strategy in which an immunogenic agent
Leonardo da Silva Neto   +13 more
doaj   +1 more source

Digital Tools for Collaborative Design Processes

open access: yes, 2021
Diverse practices of collaboration in design, research, teaching, or academia increasingly rely on digital online tools to facilitate processes of working and creating together. But a lot of the available digital platforms are not necessarily designed
Ibach, Merle, Greiner-Petter, Moritz
core   +1 more source

Introducing Experience Goals into Packaging Design [PDF]

open access: yes, 2016
Consumer experiences are an increasingly important driving force for commerce, affecting also packaging design. Yet, experience design for packages is rarely studied.
Roto, Virpi   +3 more
core   +1 more source

Active Humoral Response Reverts Tumorigenicity through Disruption of Key Signaling Pathway

open access: yesVaccines, 2022
Immune checkpoint inhibitors such as monoclonal antibodies (mAbs) are amongst the most important breakthroughs in cancer therapeutics. However, high cost and short acting time limits its affordability and clinical application.
Tracer Yong   +3 more
doaj   +1 more source

Specific and Generic Immunorecognition of Glycopeptide Antibiotics Promoted by Unique and Multiple Orientations of Hapten

open access: yesBiosensors, 2019
Conjugation chemistry does not always provide adequate spatial orientation of hapten in immunogens for the best presentation of generic or individual epitopes.
Maksim A. Burkin   +2 more
doaj   +1 more source

Hapten designs based on aldicarb for the development of a colloidal gold immunochromatographic quantitative test strip

open access: yesFrontiers in Nutrition, 2022
The common carbamate insecticide aldicarb is considered one of the most acutely toxic pesticides. Herein, rational design was used to synthesize two haptens with spacers of different carbon chain lengths. The haptens were then used to immunize mice.
Hong Shen   +20 more
doaj   +1 more source

Design and Synthesis of Immunoconjugates and Development of an Indirect ELISA for Rapid Detection of 3, 5-Dinitrosalicyclic Acid Hydrazide

open access: yesMolecules, 2008
In this study novel immunoconjugates were designed, synthesized and then used to develop a rapid, specific and sensitive indirect ELISA method to directly detect residues of 3,5-dinitrosalicyclic acid hydrazide (DNSH), a toxic metabolite of nifursol ...
Yuan-Ming Sun   +6 more
doaj   +1 more source

Requests from Companies and Requirements for Design Education in Brazil: where do they meet? [PDF]

open access: yes, 2018
In this paper, we study what companies request from applicants for graphic design positions in Brazil. Based on a document analysis of 371 job advertisements, we uncover 35 different types of requests which we structure in terms of (1) Design ...
Person, Oscar   +10 more
core   +1 more source

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